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Results: 1 to 20 of 127

1.

Distinct roles of the methylcytosine oxidases Tet1 and Tet2 in mouse embryonic stem cells.

Huang Y, Chavez L, Chang X, Wang X, Pastor WA, Kang J, Zepeda-Martínez JA, Pape UJ, Jacobsen SE, Peters B, Rao A.

Proc Natl Acad Sci U S A. 2014 Jan 28;111(4):1361-6. doi: 10.1073/pnas.1322921111. Epub 2014 Jan 13.

PMID:
24474761
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Dynamic regulation of 5-hydroxymethylcytosine in mouse ES cells and during differentiation.

Ficz G, Branco MR, Seisenberger S, Santos F, Krueger F, Hore TA, Marques CJ, Andrews S, Reik W.

Nature. 2011 May 19;473(7347):398-402. doi: 10.1038/nature10008. Epub 2011 Apr 3.

PMID:
21460836
[PubMed - indexed for MEDLINE]
3.

PRDM14 promotes active DNA demethylation through the ten-eleven translocation (TET)-mediated base excision repair pathway in embryonic stem cells.

Okashita N, Kumaki Y, Ebi K, Nishi M, Okamoto Y, Nakayama M, Hashimoto S, Nakamura T, Sugasawa K, Kojima N, Takada T, Okano M, Seki Y.

Development. 2014 Jan;141(2):269-80. doi: 10.1242/dev.099622. Epub 2013 Dec 11.

PMID:
24335252
[PubMed - indexed for MEDLINE]
Free Article
4.

Tet1 and 5-hydroxymethylation: a genome-wide view in mouse embryonic stem cells.

Wu H, Zhang Y.

Cell Cycle. 2011 Aug 1;10(15):2428-36. Epub 2011 Aug 1.

PMID:
21750410
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Stage-specific roles for tet1 and tet2 in DNA demethylation in primordial germ cells.

Vincent JJ, Huang Y, Chen PY, Feng S, Calvopiña JH, Nee K, Lee SA, Le T, Yoon AJ, Faull K, Fan G, Rao A, Jacobsen SE, Pellegrini M, Clark AT.

Cell Stem Cell. 2013 Apr 4;12(4):470-8. doi: 10.1016/j.stem.2013.01.016. Epub 2013 Feb 14.

PMID:
23415914
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Genome-wide regulation of 5hmC, 5mC, and gene expression by Tet1 hydroxylase in mouse embryonic stem cells.

Xu Y, Wu F, Tan L, Kong L, Xiong L, Deng J, Barbera AJ, Zheng L, Zhang H, Huang S, Min J, Nicholson T, Chen T, Xu G, Shi Y, Zhang K, Shi YG.

Mol Cell. 2011 May 20;42(4):451-64. doi: 10.1016/j.molcel.2011.04.005. Epub 2011 Apr 21.

PMID:
21514197
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Acute depletion of Tet1-dependent 5-hydroxymethylcytosine levels impairs LIF/Stat3 signaling and results in loss of embryonic stem cell identity.

Freudenberg JM, Ghosh S, Lackford BL, Yellaboina S, Zheng X, Li R, Cuddapah S, Wade PA, Hu G, Jothi R.

Nucleic Acids Res. 2012 Apr;40(8):3364-77. doi: 10.1093/nar/gkr1253. Epub 2011 Dec 30.

PMID:
22210859
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Vitamin C induces Tet-dependent DNA demethylation and a blastocyst-like state in ES cells.

Blaschke K, Ebata KT, Karimi MM, Zepeda-Martínez JA, Goyal P, Mahapatra S, Tam A, Laird DJ, Hirst M, Rao A, Lorincz MC, Ramalho-Santos M.

Nature. 2013 Aug 8;500(7461):222-6. doi: 10.1038/nature12362. Epub 2013 Jun 30.

PMID:
23812591
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Tet1 and Tet2 regulate 5-hydroxymethylcytosine production and cell lineage specification in mouse embryonic stem cells.

Koh KP, Yabuuchi A, Rao S, Huang Y, Cunniff K, Nardone J, Laiho A, Tahiliani M, Sommer CA, Mostoslavsky G, Lahesmaa R, Orkin SH, Rodig SJ, Daley GQ, Rao A.

Cell Stem Cell. 2011 Feb 4;8(2):200-13. doi: 10.1016/j.stem.2011.01.008.

PMID:
21295276
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Ten-eleven translocation 1 (Tet1) is regulated by O-linked N-acetylglucosamine transferase (Ogt) for target gene repression in mouse embryonic stem cells.

Shi FT, Kim H, Lu W, He Q, Liu D, Goodell MA, Wan M, Songyang Z.

J Biol Chem. 2013 Jul 19;288(29):20776-84. doi: 10.1074/jbc.M113.460386. Epub 2013 May 31.

PMID:
23729667
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Combined deficiency of Tet1 and Tet2 causes epigenetic abnormalities but is compatible with postnatal development.

Dawlaty MM, Breiling A, Le T, Raddatz G, Barrasa MI, Cheng AW, Gao Q, Powell BE, Li Z, Xu M, Faull KF, Lyko F, Jaenisch R.

Dev Cell. 2013 Feb 11;24(3):310-23. doi: 10.1016/j.devcel.2012.12.015. Epub 2013 Jan 24.

PMID:
23352810
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Oct4 and the small molecule inhibitor, SC1, regulates Tet2 expression in mouse embryonic stem cells.

Wu Y, Guo Z, Liu Y, Tang B, Wang Y, Yang L, Du J, Zhang Y.

Mol Biol Rep. 2013 Apr;40(4):2897-906. doi: 10.1007/s11033-012-2305-5. Epub 2012 Dec 20.

PMID:
23254757
[PubMed - indexed for MEDLINE]
13.

Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification.

Ito S, D'Alessio AC, Taranova OV, Hong K, Sowers LC, Zhang Y.

Nature. 2010 Aug 26;466(7310):1129-33. doi: 10.1038/nature09303.

PMID:
20639862
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Tet proteins can convert 5-methylcytosine to 5-formylcytosine and 5-carboxylcytosine.

Ito S, Shen L, Dai Q, Wu SC, Collins LB, Swenberg JA, He C, Zhang Y.

Science. 2011 Sep 2;333(6047):1300-3. doi: 10.1126/science.1210597. Epub 2011 Jul 21.

PMID:
21778364
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Dual functions of Tet1 in transcriptional regulation in mouse embryonic stem cells.

Wu H, D'Alessio AC, Ito S, Xia K, Wang Z, Cui K, Zhao K, Sun YE, Zhang Y.

Nature. 2011 May 19;473(7347):389-93. doi: 10.1038/nature09934. Epub 2011 Mar 30.

PMID:
21451524
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Modulation of TET2 expression and 5-methylcytosine oxidation by the CXXC domain protein IDAX.

Ko M, An J, Bandukwala HS, Chavez L, Aijö T, Pastor WA, Segal MF, Li H, Koh KP, Lähdesmäki H, Hogan PG, Aravind L, Rao A.

Nature. 2013 May 2;497(7447):122-6. doi: 10.1038/nature12052. Epub 2013 Apr 7.

PMID:
23563267
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Distinct and overlapping control of 5-methylcytosine and 5-hydroxymethylcytosine by the TET proteins in human cancer cells.

Putiri EL, Tiedemann RL, Thompson JJ, Liu C, Ho T, Choi JH, Robertson KD.

Genome Biol. 2014 Jun 23;15(6):R81. doi: 10.1186/gb-2014-15-6-r81.

PMID:
24958354
[PubMed - in process]
Free PMC Article
18.

Genome-wide analysis of 5-hydroxymethylcytosine distribution reveals its dual function in transcriptional regulation in mouse embryonic stem cells.

Wu H, D'Alessio AC, Ito S, Wang Z, Cui K, Zhao K, Sun YE, Zhang Y.

Genes Dev. 2011 Apr 1;25(7):679-84. doi: 10.1101/gad.2036011.

PMID:
21460036
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Different roles for Tet1 and Tet2 proteins in reprogramming-mediated erasure of imprints induced by EGC fusion.

Piccolo FM, Bagci H, Brown KE, Landeira D, Soza-Ried J, Feytout A, Mooijman D, Hajkova P, Leitch HG, Tada T, Kriaucionis S, Dawlaty MM, Jaenisch R, Merkenschlager M, Fisher AG.

Mol Cell. 2013 Mar 28;49(6):1023-33. doi: 10.1016/j.molcel.2013.01.032. Epub 2013 Feb 28. Erratum in: Mol Cell. 2013 Mar 28;49(6):1176.

PMID:
23453809
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

TET2 gene expression and 5-hydroxymethylcytosine level in multiple sclerosis peripheral blood cells.

Calabrese R, Valentini E, Ciccarone F, Guastafierro T, Bacalini MG, Ricigliano VA, Zampieri M, Annibali V, Mechelli R, Franceschi C, Salvetti M, Caiafa P.

Biochim Biophys Acta. 2014 Jul;1842(7):1130-6. doi: 10.1016/j.bbadis.2014.04.010. Epub 2014 Apr 13.

PMID:
24735979
[PubMed - indexed for MEDLINE]

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