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Results: 1 to 20 of 92

1.

Novel pyrrolidine diketopiperazines selectively inhibit melanoma cells via induction of late-onset apoptosis.

Onwuha-Ekpete L, Tack L, Knapinska A, Smith L, Kaushik G, Lavoi T, Giulianotti M, Houghten RA, Fields GB, Minond D.

J Med Chem. 2014 Feb 27;57(4):1599-608. doi: 10.1021/jm4019542. Epub 2014 Feb 5.

PMID:
24471466
[PubMed - indexed for MEDLINE]
2.

Curcumin downregulates the constitutive activity of NF-kappaB and induces apoptosis in novel mouse melanoma cells.

MarĂ­n YE, Wall BA, Wang S, Namkoong J, Martino JJ, Suh J, Lee HJ, Rabson AB, Yang CS, Chen S, Ryu JH.

Melanoma Res. 2007 Oct;17(5):274-83.

PMID:
17885582
[PubMed - indexed for MEDLINE]
3.

Tumor apoptosis induced by epoxide-containing piperazines, a new class of anti-cancer agents.

Eilon GF, Gu J, Slater LM, Hara K, Jacobs JW.

Cancer Chemother Pharmacol. 2000;45(3):183-91.

PMID:
10663635
[PubMed - indexed for MEDLINE]
4.

Identification of two novel, potent, low-liability antinociceptive compounds from the direct in vivo screening of a large mixture-based combinatorial library.

Reilley KJ, Giulianotti M, Dooley CT, Nefzi A, McLaughlin JP, Houghten RA.

AAPS J. 2010 Sep;12(3):318-29. doi: 10.1208/s12248-010-9191-3. Epub 2010 Apr 27.

PMID:
20422341
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Imatinib mesylate induction of ROS-dependent apoptosis in melanoma B16F0 cells.

Chang SP, Shen SC, Lee WR, Yang LL, Chen YC.

J Dermatol Sci. 2011 Jun;62(3):183-91. doi: 10.1016/j.jdermsci.2011.03.001. Epub 2011 Mar 16.

PMID:
21482077
[PubMed - indexed for MEDLINE]
6.

A novel hydroxamic acid compound, BMD188, demonstrates anti-prostate cancer effects by inducing apoptosis. I: In vitro studies.

Li L, Zhu Z, Joshi B, Porter AT, Tang DG.

Anticancer Res. 1999 Jan-Feb;19(1A):51-60.

PMID:
10226524
[PubMed - indexed for MEDLINE]
7.

Ligand-conjugated mesoporous silica nanorattles based on enzyme targeted prodrug delivery system for effective lung cancer therapy.

Sundarraj S, Thangam R, Sujitha MV, Vimala K, Kannan S.

Toxicol Appl Pharmacol. 2014 Mar 15;275(3):232-43. doi: 10.1016/j.taap.2014.01.012. Epub 2014 Jan 25.

PMID:
24467950
[PubMed - indexed for MEDLINE]
8.

Design, synthesis, and biological activities of pyrrolylethanoneamine derivatives, a novel class of monoamine oxidases inhibitors.

Di Santo R, Costi R, Roux A, Artico M, Befani O, Meninno T, Agostinelli E, Palmegiani P, Turini P, Cirilli R, Ferretti R, Gallinella B, La Torre F.

J Med Chem. 2005 Jun 30;48(13):4220-3.

PMID:
15974574
[PubMed - indexed for MEDLINE]
9.

N-propionyl-4-S-cysteaminylphenol induces apoptosis in B16F1 cells and mediates tumor-specific T-cell immune responses in a mouse melanoma model.

Ishii-Osai Y, Yamashita T, Tamura Y, Sato N, Ito A, Honda H, Wakamatsu K, Ito S, Nakayama E, Okura M, Jimbow K.

J Dermatol Sci. 2012 Jul;67(1):51-60. doi: 10.1016/j.jdermsci.2012.04.009. Epub 2012 May 2.

PMID:
22622238
[PubMed - indexed for MEDLINE]
10.

Targeted liposomal c-myc antisense oligodeoxynucleotides induce apoptosis and inhibit tumor growth and metastases in human melanoma models.

Pastorino F, Brignole C, Marimpietri D, Pagnan G, Morando A, Ribatti D, Semple SC, Gambini C, Allen TM, Ponzoni M.

Clin Cancer Res. 2003 Oct 1;9(12):4595-605.

PMID:
14555535
[PubMed - indexed for MEDLINE]
Free Article
11.

Synthetic phosphoethanolamine a precursor of membrane phospholipids reduce tumor growth in mice bearing melanoma B16-F10 and in vitro induce apoptosis and arrest in G2/M phase.

Ferreira AK, Meneguelo R, Marques FL, Radin A, Filho OM, Neto SC, Chierice GO, Maria DA.

Biomed Pharmacother. 2012 Oct;66(7):541-8. doi: 10.1016/j.biopha.2012.04.008. Epub 2012 May 18.

PMID:
22902646
[PubMed - indexed for MEDLINE]
12.

A novel dynamic matrix detachment model reveals a shift from apoptosis to necrosis in melanoma cells.

Tzukert K, Gorodestky R, Avrahami I, Krasny L, Shimony N, Elkin G, Nettelbeck DM, Haviv YS.

Cancer Lett. 2008 Dec 18;272(2):345-54. doi: 10.1016/j.canlet.2008.07.012. Epub 2008 Aug 23.

PMID:
18723276
[PubMed - indexed for MEDLINE]
13.

Identification of novel antitumor agents from mixture-based synthetic combinatorial libraries using cell-based assays.

Appel JR, Johnson J, Narayanan VL, Houghten RA.

Mol Divers. 1998-1999;4(2):91-102.

PMID:
10425632
[PubMed - indexed for MEDLINE]
14.

JS-K, a glutathione/glutathione S-transferase-activated nitric oxide donor of the diazeniumdiolate class with potent antineoplastic activity.

Shami PJ, Saavedra JE, Wang LY, Bonifant CL, Diwan BA, Singh SV, Gu Y, Fox SD, Buzard GS, Citro ML, Waterhouse DJ, Davies KM, Ji X, Keefer LK.

Mol Cancer Ther. 2003 Apr;2(4):409-17.

PMID:
12700285
[PubMed - indexed for MEDLINE]
Free Article
15.

Class I histone deacetylase-selective novel synthetic inhibitors potently inhibit human tumor proliferation.

Park JH, Jung Y, Kim TY, Kim SG, Jong HS, Lee JW, Kim DK, Lee JS, Kim NK, Kim TY, Bang YJ.

Clin Cancer Res. 2004 Aug 1;10(15):5271-81.

PMID:
15297431
[PubMed - indexed for MEDLINE]
Free Article
16.

Suppression of growth and hepatic metastasis of murine B16FO melanoma cells by a novel nutrient mixture.

Roomi MW, Kalinovsky T, Roomi NW, Ivanov V, Rath M, Niedzwiecki A.

Oncol Rep. 2008 Oct;20(4):809-17.

PMID:
18813822
[PubMed - indexed for MEDLINE]
17.

Identification of highly selective inhibitors of collagenase-1 from combinatorial libraries of diketopiperazines.

Szardenings AK, Antonenko V, Campbell DA, DeFrancisco N, Ida S, Shi L, Sharkov N, Tien D, Wang Y, Navre M.

J Med Chem. 1999 Apr 22;42(8):1348-57.

PMID:
10212120
[PubMed - indexed for MEDLINE]
18.

Cuprous oxide nanoparticles inhibit the growth and metastasis of melanoma by targeting mitochondria.

Wang Y, Yang F, Zhang HX, Zi XY, Pan XH, Chen F, Luo WD, Li JX, Zhu HY, Hu YP.

Cell Death Dis. 2013 Aug 29;4:e783. doi: 10.1038/cddis.2013.314.

PMID:
23990023
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Novel tubulin polymerization inhibitors overcome multidrug resistance and reduce melanoma lung metastasis.

Wang Z, Chen J, Wang J, Ahn S, Li CM, Lu Y, Loveless VS, Dalton JT, Miller DD, Li W.

Pharm Res. 2012 Nov;29(11):3040-52. doi: 10.1007/s11095-012-0726-4. Epub 2012 Mar 13.

PMID:
22410804
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Inhibition of prostate cancer cellular proteasome activity by a pyrrolidine dithiocarbamate-copper complex is associated with suppression of proliferation and induction of apoptosis.

Chen D, Peng F, Cui QC, Daniel KG, Orlu S, Liu J, Dou QP.

Front Biosci. 2005 Sep 1;10:2932-9. Review.

PMID:
15970547
[PubMed - indexed for MEDLINE]

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