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Items: 1 to 20 of 139

1.

Antinociceptive and antidiarrheal effects of pioglitazone in a rat model of diarrhoea-predominant irritable bowel syndrome: role of nitric oxide.

Paragomi P, Rahimian R, Kazemi MH, Gharedaghi MH, Khalifeh-Soltani A, Azary S, Javidan AN, Moradi K, Sakuma S, Dehpour AR.

Clin Exp Pharmacol Physiol. 2014 Feb;41(2):118-26. doi: 10.1111/1440-1681.12188.

PMID:
24471407
2.

Antinociceptive effect of chronic lithium on visceral hypersensitivity in a rat model of diarrhea-predominant irritable bowel syndrome: The role of nitric oxide pathway.

Shamshiri H, Paragomi P, Paydar MJ, Moezi L, Bahadori M, Behfar B, Ardalan FA, Dehpour AR.

J Gastroenterol Hepatol. 2009 Apr;24(4):672-80. doi: 10.1111/j.1440-1746.2008.05652.x. Epub 2008 Nov 20.

PMID:
19032458
4.

Possible involvement of PPAR-gamma receptor and nitric oxide pathway in the anticonvulsant effect of acute pioglitazone on pentylenetetrazole-induced seizures in mice.

Adabi Mohazab R, Javadi-Paydar M, Delfan B, Dehpour AR.

Epilepsy Res. 2012 Aug;101(1-2):28-35. doi: 10.1016/j.eplepsyres.2012.02.015. Epub 2012 Mar 20.

PMID:
22436324
5.

Orally administered novel cyclic pentapeptide P-317 alleviates symptoms of diarrhoea-predominant irritable bowel syndrome.

Zielińska M, Chen C, Mokrowiecka A, Cygankiewicz AI, Zakrzewski PK, Sałaga M, Małecka-Panas E, Wlaź P, Krajewska WM, Fichna J.

J Pharm Pharmacol. 2015 Feb;67(2):244-54. doi: 10.1111/jphp.12335. Epub 2014 Dec 17.

PMID:
25515402
6.

Antinociceptive effect of VSL#3 on visceral hypersensitivity in a rat model of irritable bowel syndrome: a possible action through nitric oxide pathway and enhance barrier function.

Dai C, Guandalini S, Zhao DH, Jiang M.

Mol Cell Biochem. 2012 Mar;362(1-2):43-53. doi: 10.1007/s11010-011-1126-5. Epub 2011 Oct 22.

PMID:
22020749
7.
8.

Anti-pruritic activity of pioglitazone on serotonin-induced scratching in mice: possible involvement of PPAR-gamma receptor and nitric oxide.

Shafizadeh M, Rajaba A, Imran khan M, Ostadhadi S, Rastegar H, Dehpour A.

Eur J Pharmacol. 2014 Dec 5;744:103-7. doi: 10.1016/j.ejphar.2014.10.002. Epub 2014 Oct 12.

PMID:
25310911
9.

Antidepressant-like effect of pioglitazone in the forced swimming test in mice: the role of PPAR-gamma receptor and nitric oxide pathway.

Sadaghiani MS, Javadi-Paydar M, Gharedaghi MH, Fard YY, Dehpour AR.

Behav Brain Res. 2011 Oct 31;224(2):336-43. doi: 10.1016/j.bbr.2011.06.011. Epub 2011 Jun 17.

PMID:
21704657
10.

Clinical trial: dextofisopam in the treatment of patients with diarrhoea-predominant or alternating irritable bowel syndrome.

Leventer SM, Raudibaugh K, Frissora CL, Kassem N, Keogh JC, Phillips J, Mangel AW.

Aliment Pharmacol Ther. 2008 Jan 15;27(2):197-206. Epub 2007 Oct 31.

11.

[Effect of Fagopyrum cymosum (Trev.) Meisn alcohol extract on defecation and isolated colon of diarrhea-IBS rats and its mechanism].

Liu LN, Yan J, Sun ZG.

Zhongguo Zhong Xi Yi Jie He Za Zhi. 2014 Dec;34(12):1469-75. Chinese.

PMID:
25632748
12.

Increase in neurokinin-1 receptor-mediated colonic motor response in a rat model of irritable bowel syndrome.

La JH, Kim TW, Sung TS, Kim HJ, Kim JY, Yang IS.

World J Gastroenterol. 2005 Jan 14;11(2):237-41.

13.

Role of neuronal nitric oxide synthase in colonic distension-induced hyperalgesia in distal colon of neonatal maternal separated male rats.

Tjong YW, Ip SP, Lao L, Wu J, Fong HH, Sung JJ, Berman B, Che CT.

Neurogastroenterol Motil. 2011 Jul;23(7):666-e278. doi: 10.1111/j.1365-2982.2011.01697.x. Epub 2011 Mar 16.

14.

The effects of sildenafil on rectal sensitivity and tone in patients with the irritable bowel syndrome.

Gonçalves de Medeiros MT, de Oliveira RB, dos Santos AA, de Leopoldino DM, Lima MC, Nobre RA, Nobre e Souza MÂ.

Aliment Pharmacol Ther. 2012 Mar;35(5):577-86. doi: 10.1111/j.1365-2036.2011.04977.x. Epub 2012 Jan 10.

15.

Antidepressant-like effect of atorvastatin in the forced swimming test in mice: the role of PPAR-gamma receptor and nitric oxide pathway.

Shahsavarian A, Javadi S, Jahanabadi S, Khoshnoodi M, Shamsaee J, Shafaroodi H, Mehr SE, Dehpour A.

Eur J Pharmacol. 2014 Dec 15;745:52-8. doi: 10.1016/j.ejphar.2014.10.004. Epub 2014 Oct 14.

PMID:
25446923
16.
17.

Eluxadoline benefits patients with irritable bowel syndrome with diarrhea in a phase 2 study.

Dove LS, Lembo A, Randall CW, Fogel R, Andrae D, Davenport JM, McIntyre G, Almenoff JS, Covington PS.

Gastroenterology. 2013 Aug;145(2):329-38.e1. doi: 10.1053/j.gastro.2013.04.006. Epub 2013 Apr 9.

18.

Novel mixed NOP/MOP agonist BU08070 alleviates pain and inhibits gastrointestinal motility in mouse models mimicking diarrhea-predominant irritable bowel syndrome symptoms.

Sobczak M, Cami-Kobeci G, Sałaga M, Husbands SM, Fichna J.

Eur J Pharmacol. 2014 Aug 5;736:63-9. doi: 10.1016/j.ejphar.2014.04.038. Epub 2014 May 6.

19.
20.

Antidiabetic drug pioglitazone protects the heart via activation of PPAR-gamma receptors, PI3-kinase, Akt, and eNOS pathway in a rabbit model of myocardial infarction.

Yasuda S, Kobayashi H, Iwasa M, Kawamura I, Sumi S, Narentuoya B, Yamaki T, Ushikoshi H, Nishigaki K, Nagashima K, Takemura G, Fujiwara T, Fujiwara H, Minatoguchi S.

Am J Physiol Heart Circ Physiol. 2009 May;296(5):H1558-65. doi: 10.1152/ajpheart.00712.2008. Epub 2009 Mar 13.

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