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Results: 1 to 20 of 101

1.

Novel N-substituted aminobenzamide scaffold derivatives targeting the dipeptidyl peptidase-IV enzyme.

Al-Balas QA, Sowaileh MF, Hassan MA, Qandil AM, Alzoubi KH, Mhaidat NM, Almaaytah AM, Khabour OF.

Drug Des Devel Ther. 2014 Jan 16;8:129-63. doi: 10.2147/DDDT.S53522. eCollection 2014.

PMID:
24470754
[PubMed - in process]
Free PMC Article
2.

Synthesis, evaluation and molecular docking of thiazolopyrimidine derivatives as dipeptidyl peptidase IV inhibitors.

Sharma M, Gupta M, Singh D, Kumar M, Kaur P.

Chem Biol Drug Des. 2012 Dec;80(6):918-28. doi: 10.1111/cbdd.12041. Epub 2012 Oct 12.

PMID:
22943413
[PubMed - indexed for MEDLINE]
3.

Identification of novel human dipeptidyl peptidase-IV inhibitors of natural origin (part I): virtual screening and activity assays.

Guasch L, Ojeda MJ, González-Abuín N, Sala E, Cereto-Massagué A, Mulero M, Valls C, Pinent M, Ardévol A, Garcia-Vallvé S, Pujadas G.

PLoS One. 2012;7(9):e44971. doi: 10.1371/journal.pone.0044971. Epub 2012 Sep 12.

PMID:
22984596
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Dipeptidyl peptidase IV (DPP IV) and related molecules in type 2 diabetes.

Flatt PR, Bailey CJ, Green BD.

Front Biosci. 2008 May 1;13:3648-60. Review.

PMID:
18508462
[PubMed - indexed for MEDLINE]
5.

Plasma dipeptidyl peptidase-IV activity in patients with type-2 diabetes mellitus correlates positively with HbAlc levels, but is not acutely affected by food intake.

Ryskjaer J, Deacon CF, Carr RD, Krarup T, Madsbad S, Holst J, Vilsbøll T.

Eur J Endocrinol. 2006 Sep;155(3):485-93.

PMID:
16914604
[PubMed - indexed for MEDLINE]
Free Article
6.

Design, synthesis and biological evaluation of novel imidazolone derivatives as dipeptidyl peptidase 4 inhibitors.

Liu Y, Jiang C, Wu H, Wu P, Si M, Hu Y, Liu T.

Med Chem. 2013 Nov;9(7):938-46.

PMID:
23083118
[PubMed - indexed for MEDLINE]
7.

Inhibition of dipeptidyl peptidase IV by novel inhibitors with pyrazolidine scaffold.

Cheon HG, Kim SS, Kim KR, Rhee SD, Yang SD, Ahn JH, Park SD, Lee JM, Jung WH, Lee HS, Kim HY.

Biochem Pharmacol. 2005 Jul 1;70(1):22-9.

PMID:
15893294
[PubMed - indexed for MEDLINE]
8.

RBx-0597, a potent, selective and slow-binding inhibitor of dipeptidyl peptidase-IV for the treatment of type 2 diabetes.

Singh S, Roy S, Sethi S, Benjamin B, Sundaram S, Khanna V, Kandalkar SR, Pal C, Kant R, Patra AK, Rayasam G, Mittra S, Saini KS, Paliwal J, Chugh A, Ahmed S, Sattigeri J, Cliff I, Ray A, Bansal VS, Bhatnagar PK, Davis JA.

Eur J Pharmacol. 2011 Feb 10;652(1-3):157-63. doi: 10.1016/j.ejphar.2010.06.001. Epub 2010 Jun 9. Erratum in: Eur J Pharmacol. 2011 Mar 25;655(1-3):121. multiple author names added.

PMID:
20540938
[PubMed - indexed for MEDLINE]
9.

Design, Synthesis and Biological Evaluation of N4-Sulfonamido-Succinamic, Phthalamic, Acrylic and Benzoyl Acetic Acid Derivatives as Potential DPP IV Inhibitors.

Khalaf RA, Sheikha GA, Al-Sha'er M, Taha M.

Open Med Chem J. 2013 Nov 29;7:39-48. doi: 10.2174/1874104501307010039. eCollection 2013.

PMID:
24358058
[PubMed]
Free PMC Article
10.

KR-62436, 6-{2-[2-(5-cyano-4,5-dihydropyrazol-1-yl)-2-oxoethylamino]ethylamino}nicotinonitrile, is a novel dipeptidyl peptidase-IV (DPP-IV) inhibitor with anti-hyperglycemic activity.

Kim KR, Rhee SD, Kim HY, Jung WH, Yang SD, Kim SS, Ahn JH, Cheon HG.

Eur J Pharmacol. 2005 Jul 25;518(1):63-70.

PMID:
16106524
[PubMed - indexed for MEDLINE]
11.

Glutamic acid analogues as potent dipeptidyl peptidase IV and 8 inhibitors.

Lu IL, Lee SJ, Tsu H, Wu SY, Kao KH, Chien CH, Chang YY, Chen YS, Cheng JH, Chang CN, Chen TW, Chang SP, Chen X, Jiaang WT.

Bioorg Med Chem Lett. 2005 Jul 1;15(13):3271-5.

PMID:
15927466
[PubMed - indexed for MEDLINE]
12.

Insulinotropic actions of nateglinide in type 2 diabetic patients and effects on dipeptidyl peptidase-IV activity and glucose-dependent insulinotropic polypeptide degradation.

McKillop AM, Duffy NA, Lindsay JR, Green BD, Patterson S, O'Harte FP, Bell PM, Flatt PR.

Eur J Endocrinol. 2009 Dec;161(6):877-85. doi: 10.1530/EJE-09-0547. Epub 2009 Sep 15.

PMID:
19755410
[PubMed - indexed for MEDLINE]
Free Article
13.

7-But-2-ynyl-9-(6-methoxy-pyridin-3-yl)-6-piperazin-1-yl-7,9-dihydro-purin-8-one is a novel competitive and selective inhibitor of dipeptidyl peptidase IV with an antihyperglycemic activity.

Yamazaki K, Yasuda N, Inoue T, Nagakura T, Kira K, Shinoda M, Saeki T, Tanaka I.

J Pharmacol Exp Ther. 2006 Dec;319(3):1253-7. Epub 2006 Sep 15.

PMID:
16980568
[PubMed - indexed for MEDLINE]
Free Article
14.

Mechanism of action of inhibitors of dipeptidyl-peptidase-4 (DPP-4).

Thornberry NA, Gallwitz B.

Best Pract Res Clin Endocrinol Metab. 2009 Aug;23(4):479-86. doi: 10.1016/j.beem.2009.03.004.

PMID:
19748065
[PubMed - indexed for MEDLINE]
15.

Synthesis, biological assay in vitro and molecular docking studies of new imidazopyrazinone derivatives as potential dipeptidyl peptidase IV inhibitors.

Zhu Y, Xia S, Zhu M, Yi W, Cheng J, Song G, Li Z, Lu P.

Eur J Med Chem. 2010 Nov;45(11):4953-62. doi: 10.1016/j.ejmech.2010.08.002. Epub 2010 Aug 12.

PMID:
20800322
[PubMed - indexed for MEDLINE]
16.

Therapeutic potential of dipeptidyl peptidase-IV inhibitors in patients with diabetes mellitus.

Moore KB, Saudek CD.

Am J Ther. 2008 Sep-Oct;15(5):484-91. doi: 10.1097/MJT.0b013e3180ed42dc. Review.

PMID:
18806525
[PubMed - indexed for MEDLINE]
17.

Dipeptidyl peptidase IV inhibitors and diabetes therapy.

McIntosh CH.

Front Biosci. 2008 Jan 1;13:1753-73. Review.

PMID:
17981665
[PubMed - indexed for MEDLINE]
18.

A novel long acting DPP-IV inhibitor PKF-275-055 stimulates β-cell proliferation resulting in improved glucose homeostasis in diabetic rats.

Akarte AS, Srinivasan BP, Gandhi S.

Biochem Pharmacol. 2012 Jan 15;83(2):241-52. doi: 10.1016/j.bcp.2011.10.003. Epub 2011 Oct 12.

PMID:
22015634
[PubMed - indexed for MEDLINE]
19.

Pharmacological profile of ASP8497, a novel, selective, and competitive dipeptidyl peptidase-IV inhibitor, in vitro and in vivo.

Someya Y, Tahara A, Nakano R, Matsuyama-Yokono A, Nagase I, Fukunaga Y, Takasu T, Hayakawa M, Shibasaki M.

Naunyn Schmiedebergs Arch Pharmacol. 2008 May;377(3):209-17. doi: 10.1007/s00210-008-0277-8. Epub 2008 Apr 9.

PMID:
18398600
[PubMed - indexed for MEDLINE]
20.

Clinical implications of cardiovascular preventing pleiotropic effects of dipeptidyl peptidase-4 inhibitors.

Chrysant SG, Chrysant GS.

Am J Cardiol. 2012 Jun 1;109(11):1681-5. doi: 10.1016/j.amjcard.2012.01.398. Epub 2012 Mar 16. Review.

PMID:
22425330
[PubMed - indexed for MEDLINE]

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