Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Results: 1 to 20 of 86

1.

Requirement of enhanced Survival Motoneuron protein imposed during neuromuscular junction maturation.

Kariya S, Obis T, Garone C, Akay T, Sera F, Iwata S, Homma S, Monani UR.

J Clin Invest. 2014 Feb 3;124(2):785-800. doi: 10.1172/JCI72017. Epub 2014 Jan 27.

PMID:
24463453
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Limited phenotypic effects of selectively augmenting the SMN protein in the neurons of a mouse model of severe spinal muscular atrophy.

Lee AJ, Awano T, Park GH, Monani UR.

PLoS One. 2012;7(9):e46353. doi: 10.1371/journal.pone.0046353. Epub 2012 Sep 27.

PMID:
23029491
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Survival motor neuron protein in motor neurons determines synaptic integrity in spinal muscular atrophy.

Martinez TL, Kong L, Wang X, Osborne MA, Crowder ME, Van Meerbeke JP, Xu X, Davis C, Wooley J, Goldhamer DJ, Lutz CM, Rich MM, Sumner CJ.

J Neurosci. 2012 Jun 20;32(25):8703-15. doi: 10.1523/JNEUROSCI.0204-12.2012.

PMID:
22723710
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

A critical smn threshold in mice dictates onset of an intermediate spinal muscular atrophy phenotype associated with a distinct neuromuscular junction pathology.

Bowerman M, Murray LM, Beauvais A, Pinheiro B, Kothary R.

Neuromuscul Disord. 2012 Mar;22(3):263-76. doi: 10.1016/j.nmd.2011.09.007. Epub 2011 Nov 8.

PMID:
22071333
[PubMed - indexed for MEDLINE]
5.

Zebrafish survival motor neuron mutants exhibit presynaptic neuromuscular junction defects.

Boon KL, Xiao S, McWhorter ML, Donn T, Wolf-Saxon E, Bohnsack MT, Moens CB, Beattie CE.

Hum Mol Genet. 2009 Oct 1;18(19):3615-25. doi: 10.1093/hmg/ddp310. Epub 2009 Jul 10.

PMID:
19592581
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

SMN-targeted therapeutics for spinal muscular atrophy: are we SMArt enough yet?

Swoboda KJ.

J Clin Invest. 2014 Feb 3;124(2):487-90. doi: 10.1172/JCI74142. Epub 2014 Jan 27.

PMID:
24463455
[PubMed - indexed for MEDLINE]
7.

Improvement of neuromuscular synaptic phenotypes without enhanced survival and motor function in severe spinal muscular atrophy mice selectively rescued in motor neurons.

Paez-Colasante X, Seaberg B, Martinez TL, Kong L, Sumner CJ, Rimer M.

PLoS One. 2013 Sep 23;8(9):e75866. doi: 10.1371/journal.pone.0075866. eCollection 2013.

PMID:
24086650
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Modeling spinal muscular atrophy in Drosophila.

Chang HC, Dimlich DN, Yokokura T, Mukherjee A, Kankel MW, Sen A, Sridhar V, Fulga TA, Hart AC, Van Vactor D, Artavanis-Tsakonas S.

PLoS One. 2008 Sep 15;3(9):e3209. doi: 10.1371/journal.pone.0003209.

PMID:
18791638
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Postsymptomatic restoration of SMN rescues the disease phenotype in a mouse model of severe spinal muscular atrophy.

Lutz CM, Kariya S, Patruni S, Osborne MA, Liu D, Henderson CE, Li DK, Pellizzoni L, Rojas J, Valenzuela DM, Murphy AJ, Winberg ML, Monani UR.

J Clin Invest. 2011 Aug;121(8):3029-41. doi: 10.1172/JCI57291. Epub 2011 Jul 25.

PMID:
21785219
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Selective vulnerability of motor neurons and dissociation of pre- and post-synaptic pathology at the neuromuscular junction in mouse models of spinal muscular atrophy.

Murray LM, Comley LH, Thomson D, Parkinson N, Talbot K, Gillingwater TH.

Hum Mol Genet. 2008 Apr 1;17(7):949-62. Epub 2007 Dec 8.

PMID:
18065780
[PubMed - indexed for MEDLINE]
Free Article
11.

Temporal requirement for SMN in motoneuron development.

Hao le T, Duy PQ, Jontes JD, Wolman M, Granato M, Beattie CE.

Hum Mol Genet. 2013 Jul 1;22(13):2612-25. doi: 10.1093/hmg/ddt110. Epub 2013 Mar 3.

PMID:
23459934
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Mutant superoxide dismutase 1 (SOD1), a cause of amyotrophic lateral sclerosis, disrupts the recruitment of SMN, the spinal muscular atrophy protein to nuclear Cajal bodies.

Kariya S, Re DB, Jacquier A, Nelson K, Przedborski S, Monani UR.

Hum Mol Genet. 2012 Aug 1;21(15):3421-34. doi: 10.1093/hmg/dds174. Epub 2012 May 11.

PMID:
22581780
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

A transgene carrying an A2G missense mutation in the SMN gene modulates phenotypic severity in mice with severe (type I) spinal muscular atrophy.

Monani UR, Pastore MT, Gavrilina TO, Jablonka S, Le TT, Andreassi C, DiCocco JM, Lorson C, Androphy EJ, Sendtner M, Podell M, Burghes AH.

J Cell Biol. 2003 Jan 6;160(1):41-52. Epub 2003 Jan 6.

PMID:
12515823
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Chronic treatment with lithium does not improve neuromuscular phenotype in a mouse model of severe spinal muscular atrophy.

Dachs E, Piedrafita L, Hereu M, Esquerda JE, Calderó J.

Neuroscience. 2013 Oct 10;250:417-33. doi: 10.1016/j.neuroscience.2013.07.026. Epub 2013 Jul 19.

PMID:
23876328
[PubMed - indexed for MEDLINE]
15.

Neurotransmitter release in motor nerve terminals of a mouse model of mild spinal muscular atrophy.

Ruiz R, Tabares L.

J Anat. 2014 Jan;224(1):74-84. doi: 10.1111/joa.12038. Epub 2013 Mar 13.

PMID:
23489475
[PubMed - indexed for MEDLINE]
16.

Increasing expression and decreasing degradation of SMN ameliorate the spinal muscular atrophy phenotype in mice.

Kwon DY, Motley WW, Fischbeck KH, Burnett BG.

Hum Mol Genet. 2011 Sep 15;20(18):3667-77. doi: 10.1093/hmg/ddr288. Epub 2011 Jun 21.

PMID:
21693563
[PubMed - indexed for MEDLINE]
Free PMC Article
17.
18.

Severe neuromuscular denervation of clinically relevant muscles in a mouse model of spinal muscular atrophy.

Ling KK, Gibbs RM, Feng Z, Ko CP.

Hum Mol Genet. 2012 Jan 1;21(1):185-95. doi: 10.1093/hmg/ddr453. Epub 2011 Oct 3.

PMID:
21968514
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

HuD interacts with survival motor neuron protein and can rescue spinal muscular atrophy-like neuronal defects.

Hubers L, Valderrama-Carvajal H, Laframboise J, Timbers J, Sanchez G, Côté J.

Hum Mol Genet. 2011 Feb 1;20(3):553-79. doi: 10.1093/hmg/ddq500. Epub 2010 Nov 18.

PMID:
21088113
[PubMed - indexed for MEDLINE]
Free Article
20.

Rescue of the spinal muscular atrophy phenotype in a mouse model by early postnatal delivery of SMN.

Foust KD, Wang X, McGovern VL, Braun L, Bevan AK, Haidet AM, Le TT, Morales PR, Rich MM, Burghes AH, Kaspar BK.

Nat Biotechnol. 2010 Mar;28(3):271-4. doi: 10.1038/nbt.1610. Epub 2010 Feb 28.

PMID:
20190738
[PubMed - indexed for MEDLINE]
Free PMC Article

Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Supplemental Content

Write to the Help Desk