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Results: 1 to 20 of 103

1.

Dimeric structure of pseudokinase RNase L bound to 2-5A reveals a basis for interferon-induced antiviral activity.

Huang H, Zeqiraj E, Dong B, Jha BK, Duffy NM, Orlicky S, Thevakumaran N, Talukdar M, Pillon MC, Ceccarelli DF, Wan LC, Juang YC, Mao DY, Gaughan C, Brinton MA, Perelygin AA, Kourinov I, Guarné A, Silverman RH, Sicheri F.

Mol Cell. 2014 Jan 23;53(2):221-34. doi: 10.1016/j.molcel.2013.12.025.

PMID:
24462203
[PubMed - indexed for MEDLINE]
2.

2-5A induces a conformational change in the ankyrin-repeat domain of RNase L.

Nakanishi M, Goto Y, Kitade Y.

Proteins. 2005 Jul 1;60(1):131-8.

PMID:
15849753
[PubMed - indexed for MEDLINE]
3.

Molecular basis for recognition of 2',5'-linked oligoadenylates by the N-terminal ankyrin repeat domain of human ribonuclease L.

Tanaka N, Nakanishi M, Kusakabe Y, Goto Y, Kitade Y, Nakamura KT.

Nucleic Acids Symp Ser (Oxf). 2005;(49):323-4.

PMID:
17150764
[PubMed - indexed for MEDLINE]
Free Article
4.

Structural basis for recognition of 2',5'-linked oligoadenylates by human ribonuclease L.

Tanaka N, Nakanishi M, Kusakabe Y, Goto Y, Kitade Y, Nakamura KT.

EMBO J. 2004 Oct 13;23(20):3929-38. Epub 2004 Sep 23.

PMID:
15385955
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Functional characterization of 2',5'-linked oligoadenylate binding determinant of human RNase L.

Nakanishi M, Tanaka N, Mizutani Y, Mochizuki M, Ueno Y, Nakamura KT, Kitade Y.

J Biol Chem. 2005 Dec 16;280(50):41694-9. Epub 2005 Oct 17.

PMID:
16234235
[PubMed - indexed for MEDLINE]
Free Article
6.

Introduction of 8-methyladenosine into 2', 5'-oligoadenylate (2-5A) 2'-terminus induces dramatic shift in binding site of RNase L.

Nagaoka K, Kito S, Kitamura Y, Ueno Y, Kitade Y.

Nucleic Acids Symp Ser (Oxf). 2009;(53):123-4. doi: 10.1093/nass/nrp062.

PMID:
19749291
[PubMed - indexed for MEDLINE]
Free Article
7.

5'-O-dephosphorylated 2',5'-oligoadenylate (2-5A) with 8-methyladenosine at the 2'-terminus activates human RNase L.

Nagaoka K, Kitamura Y, Ueno Y, Kitade Y.

Bioorg Med Chem Lett. 2010 Feb 1;20(3):1186-8. doi: 10.1016/j.bmcl.2009.12.005. Epub 2009 Dec 4.

PMID:
20022497
[PubMed - indexed for MEDLINE]
8.

Small-molecule activators of RNase L with broad-spectrum antiviral activity.

Thakur CS, Jha BK, Dong B, Das Gupta J, Silverman KM, Mao H, Sawai H, Nakamura AO, Banerjee AK, Gudkov A, Silverman RH.

Proc Natl Acad Sci U S A. 2007 Jun 5;104(23):9585-90. Epub 2007 May 29.

PMID:
17535916
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

A viral RNA competitively inhibits the antiviral endoribonuclease domain of RNase L.

Townsend HL, Jha BK, Han JQ, Maluf NK, Silverman RH, Barton DJ.

RNA. 2008 Jun;14(6):1026-36. doi: 10.1261/rna.958908. Epub 2008 Apr 21.

PMID:
18426919
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Mechanistic insights into RNase L through use of an MDMX-derived multi-functional protein domain.

Garvie CW, Vasanthavada K, Xiang Q.

Biochim Biophys Acta. 2013 Aug;1834(8):1562-71. doi: 10.1016/j.bbapap.2013.04.010. Epub 2013 Apr 19.

PMID:
23608948
[PubMed - indexed for MEDLINE]
Free Article
11.

Alternative function of a protein kinase homology domain in 2', 5'-oligoadenylate dependent RNase L.

Dong B, Silverman RH.

Nucleic Acids Res. 1999 Jan 15;27(2):439-45.

PMID:
9862963
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Small self-RNA generated by RNase L amplifies antiviral innate immunity.

Malathi K, Dong B, Gale M Jr, Silverman RH.

Nature. 2007 Aug 16;448(7155):816-9. Epub 2007 Jul 25.

PMID:
17653195
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Characterization of RNABP, an RNA binding protein that associates with RNase L.

Le Roy F, Laskowska A, Silhol M, Salehzada T, Bisbal C.

J Interferon Cytokine Res. 2000 Jul;20(7):635-44.

PMID:
10926206
[PubMed - indexed for MEDLINE]
14.

Comparative study on the biological properties of 2',5'-oligoadenylate derivatives with purified human RNase L expressed in E. coli.

Yoshimura A, Nakanishi M, Yatome C, Kitade Y.

J Biochem. 2002 Oct;132(4):643-8.

PMID:
12359081
[PubMed - indexed for MEDLINE]
Free Article
15.

Solid-phase synthesis of 5'-triphosphate 2'-5'-oligoadenylates analogs with 3'-O-biolabile groups and their evaluation as RNase L activators and antiviral drugs.

Thillier Y, Stevens SK, Moy C, Taylor J, Vasseur JJ, Beigelman L, Debart F.

Bioorg Med Chem. 2013 Sep 1;21(17):5461-9. doi: 10.1016/j.bmc.2013.06.008. Epub 2013 Jun 13.

PMID:
23810677
[PubMed - indexed for MEDLINE]
16.

Expression of interferon-inducible recombinant human RNase L causes RNA degradation and inhibition of cell growth in Escherichia coli.

Pandey M, Rath PC.

Biochem Biophys Res Commun. 2004 Apr 30;317(2):586-97.

PMID:
15063798
[PubMed - indexed for MEDLINE]
17.

A bipartite model of 2-5A-dependent RNase L.

Dong B, Silverman RH.

J Biol Chem. 1997 Aug 29;272(35):22236-42.

PMID:
9268370
[PubMed - indexed for MEDLINE]
Free Article
18.

Innate immune messenger 2-5A tethers human RNase L into active high-order complexes.

Han Y, Whitney G, Donovan J, Korennykh A.

Cell Rep. 2012 Oct 25;2(4):902-13. doi: 10.1016/j.celrep.2012.09.004. Epub 2012 Oct 19.

PMID:
23084743
[PubMed - indexed for MEDLINE]
Free Article
19.

Interferon action and apoptosis are defective in mice devoid of 2',5'-oligoadenylate-dependent RNase L.

Zhou A, Paranjape J, Brown TL, Nie H, Naik S, Dong B, Chang A, Trapp B, Fairchild R, Colmenares C, Silverman RH.

EMBO J. 1997 Nov 3;16(21):6355-63.

PMID:
9351818
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Synthesis of 2-5As possessing base-modified adenosines and their activities to human recombinant RNase L.

Kitade Y, Tanida Y, Tuboi T, Yoshimura A, Nakanishi M, Yatome C.

Nucleic Acids Symp Ser. 2000;(44):29-30.

PMID:
12903252
[PubMed - indexed for MEDLINE]
Free Article

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