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Results: 1 to 20 of 101

1.

Selection of peptide inhibitors for double-stranded RNA-dependent protein kinase PKR.

Du MJ, Zhang HK, He AJ, Chang YS, Yang Y, Wang Y, Zhang CZ, Cao Y.

Biochemistry (Mosc). 2013 Nov;78(11):1254-62. doi: 10.1134/S0006297913110059.

PMID:
24460939
[PubMed - in process]
Free Article
2.

The double-stranded RNA-activated protein kinase PKR is dispensable for regulation of translation initiation in response to either calcium mobilization from the endoplasmic reticulum or essential amino acid starvation.

Kimball SR, Clemens MJ, Tilleray VJ, Wek RC, Horetsky RL, Jefferson LS.

Biochem Biophys Res Commun. 2001 Jan 12;280(1):293-300.

PMID:
11162513
[PubMed - indexed for MEDLINE]
4.

Autophosphorylation in the activation loop is required for full kinase activity in vivo of human and yeast eukaryotic initiation factor 2alpha kinases PKR and GCN2.

Romano PR, Garcia-Barrio MT, Zhang X, Wang Q, Taylor DR, Zhang F, Herring C, Mathews MB, Qin J, Hinnebusch AG.

Mol Cell Biol. 1998 Apr;18(4):2282-97.

PMID:
9528799
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Involvement of double-stranded RNA-dependent protein kinase and phosphorylation of eukaryotic initiation factor-2alpha in neuronal degeneration.

Chang RC, Suen KC, Ma CH, Elyaman W, Ng HK, Hugon J.

J Neurochem. 2002 Dec;83(5):1215-25.

PMID:
12437593
[PubMed - indexed for MEDLINE]
6.
7.

Upstream signaling pathways leading to the activation of double-stranded RNA-dependent serine/threonine protein kinase in beta-amyloid peptide neurotoxicity.

Suen KC, Yu MS, So KF, Chang RC, Hugon J.

J Biol Chem. 2003 Dec 12;278(50):49819-27. Epub 2003 Sep 15.

PMID:
12975376
[PubMed - indexed for MEDLINE]
Free Article
8.

Functional domains and the antiviral effect of the double-stranded RNA-dependent protein kinase PKR from Paralichthys olivaceus.

Zhu R, Zhang YB, Zhang QY, Gui JF.

J Virol. 2008 Jul;82(14):6889-901. doi: 10.1128/JVI.02385-07. Epub 2008 Apr 30.

PMID:
18448522
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Double-stranded RNA-activated protein kinase PKR of fishes and amphibians: varying the number of double-stranded RNA binding domains and lineage-specific duplications.

Rothenburg S, Deigendesch N, Dey M, Dever TE, Tazi L.

BMC Biol. 2008 Mar 3;6:12. doi: 10.1186/1741-7007-6-12.

PMID:
18312693
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Mutations in the double-stranded RNA-activated protein kinase insert region that uncouple catalysis from eIF2alpha binding.

Cai R, Williams BR.

J Biol Chem. 1998 May 1;273(18):11274-80.

PMID:
9556619
[PubMed - indexed for MEDLINE]
Free Article
11.

Selection of small-molecule mediators of the RNA regulation of PKR, the RNA-dependent protein kinase.

Carlson CB, Spanggord RJ, Beal PA.

Chembiochem. 2002 Sep 2;3(9):859-65.

PMID:
12210987
[PubMed - indexed for MEDLINE]
12.

Regulation of mRNA translation and cellular signaling by hepatitis C virus nonstructural protein NS5A.

He Y, Tan SL, Tareen SU, Vijaysri S, Langland JO, Jacobs BL, Katze MG.

J Virol. 2001 Jun;75(11):5090-8.

PMID:
11333890
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Inhibition of double-stranded RNA-dependent protein kinase PKR by vaccinia virus E3: role of complex formation and the E3 N-terminal domain.

Romano PR, Zhang F, Tan SL, Garcia-Barrio MT, Katze MG, Dever TE, Hinnebusch AG.

Mol Cell Biol. 1998 Dec;18(12):7304-16.

PMID:
9819417
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

The P58 cellular inhibitor complexes with the interferon-induced, double-stranded RNA-dependent protein kinase, PKR, to regulate its autophosphorylation and activity.

Polyak SJ, Tang N, Wambach M, Barber GN, Katze MG.

J Biol Chem. 1996 Jan 19;271(3):1702-7.

PMID:
8576172
[PubMed - indexed for MEDLINE]
Free Article
15.
16.

Rift Valley fever virus NSs protein promotes post-transcriptional downregulation of protein kinase PKR and inhibits eIF2alpha phosphorylation.

Ikegami T, Narayanan K, Won S, Kamitani W, Peters CJ, Makino S.

PLoS Pathog. 2009 Feb;5(2):e1000287. doi: 10.1371/journal.ppat.1000287. Epub 2009 Feb 6.

PMID:
19197350
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Translational resistance of late alphavirus mRNA to eIF2alpha phosphorylation: a strategy to overcome the antiviral effect of protein kinase PKR.

Ventoso I, Sanz MA, Molina S, Berlanga JJ, Carrasco L, Esteban M.

Genes Dev. 2006 Jan 1;20(1):87-100.

PMID:
16391235
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Higher-order substrate recognition of eIF2alpha by the RNA-dependent protein kinase PKR.

Dar AC, Dever TE, Sicheri F.

Cell. 2005 Sep 23;122(6):887-900.

PMID:
16179258
[PubMed - indexed for MEDLINE]
Free Article
19.

Involvement of ERKs, RSK2 and PKR in UVA-induced signal transduction toward phosphorylation of eIF2alpha (Ser(51)).

Zykova TA, Zhu F, Zhang Y, Bode AM, Dong Z.

Carcinogenesis. 2007 Jul;28(7):1543-51. Epub 2007 Apr 2.

PMID:
17404396
[PubMed - indexed for MEDLINE]
Free Article
20.

Protein kinase PKR mutants resistant to the poxvirus pseudosubstrate K3L protein.

Seo EJ, Liu F, Kawagishi-Kobayashi M, Ung TL, Cao C, Dar AC, Sicheri F, Dever TE.

Proc Natl Acad Sci U S A. 2008 Nov 4;105(44):16894-9. doi: 10.1073/pnas.0805524105. Epub 2008 Oct 29.

PMID:
18971339
[PubMed - indexed for MEDLINE]
Free PMC Article

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