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Items: 1 to 20 of 119

1.

Glial cell line-derived neurotrophic factor protects against high-fat diet-induced obesity.

Mwangi SM, Nezami BG, Obukwelu B, Anitha M, Marri S, Fu P, Epperson MF, Le NA, Shanmugam M, Sitaraman SV, Tseng YH, Anania FA, Srinivasan S.

Am J Physiol Gastrointest Liver Physiol. 2014 Mar;306(6):G515-25. doi: 10.1152/ajpgi.00364.2013. Epub 2014 Jan 23.

2.

Glial cell line-derived neurotrophic factor protects against high-fat diet-induced hepatic steatosis by suppressing hepatic PPAR-╬│ expression.

Mwangi SM, Peng S, Nezami BG, Thorn N, Farris AB 3rd, Jain S, Laroui H, Merlin D, Anania F, Srinivasan S.

Am J Physiol Gastrointest Liver Physiol. 2016 Jan 15;310(2):G103-16. doi: 10.1152/ajpgi.00196.2015. Epub 2015 Nov 12.

PMID:
26564715
3.

Hepatic SIRT1 attenuates hepatic steatosis and controls energy balance in mice by inducing fibroblast growth factor 21.

Li Y, Wong K, Giles A, Jiang J, Lee JW, Adams AC, Kharitonenkov A, Yang Q, Gao B, Guarente L, Zang M.

Gastroenterology. 2014 Feb;146(2):539-49.e7. doi: 10.1053/j.gastro.2013.10.059. Epub 2013 Nov 1.

4.

Glucosamine enhances body weight gain and reduces insulin response in mice fed chow diet but mitigates obesity, insulin resistance and impaired glucose tolerance in mice high-fat diet.

Hwang JS, Park JW, Nam MS, Cho H, Han IO.

Metabolism. 2015 Mar;64(3):368-79. doi: 10.1016/j.metabol.2014.11.005. Epub 2014 Nov 20.

PMID:
25516476
5.

A combination of exercise and capsinoid supplementation additively suppresses diet-induced obesity by increasing energy expenditure in mice.

Ohyama K, Nogusa Y, Suzuki K, Shinoda K, Kajimura S, Bannai M.

Am J Physiol Endocrinol Metab. 2015 Feb 15;308(4):E315-23. doi: 10.1152/ajpendo.00354.2014. Epub 2014 Dec 16.

6.

Improved glucose control and reduced body fat mass in free fatty acid receptor 2-deficient mice fed a high-fat diet.

Bjursell M, Admyre T, G├Âransson M, Marley AE, Smith DM, Oscarsson J, Bohlooly-Y M.

Am J Physiol Endocrinol Metab. 2011 Jan;300(1):E211-20. doi: 10.1152/ajpendo.00229.2010. Epub 2010 Oct 19.

7.

Triggering receptor expressed on myeloid cells 2 (TREM2) promotes adipogenesis and diet-induced obesity.

Park M, Yi JW, Kim EM, Yoon IJ, Lee EH, Lee HY, Ji KY, Lee KH, Jang JH, Oh SS, Yun CH, Kim SH, Lee KM, Song MG, Kim DH, Kang HS.

Diabetes. 2015 Jan;64(1):117-27. doi: 10.2337/db13-1869. Epub 2014 Aug 11.

8.

Targeted overexpression of inducible 6-phosphofructo-2-kinase in adipose tissue increases fat deposition but protects against diet-induced insulin resistance and inflammatory responses.

Huo Y, Guo X, Li H, Xu H, Halim V, Zhang W, Wang H, Fan YY, Ong KT, Woo SL, Chapkin RS, Mashek DG, Chen Y, Dong H, Lu F, Wei L, Wu C.

J Biol Chem. 2012 Jun 15;287(25):21492-500. doi: 10.1074/jbc.M112.370379. Epub 2012 May 3.

9.

The constitutive androstane receptor is an anti-obesity nuclear receptor that improves insulin sensitivity.

Gao J, He J, Zhai Y, Wada T, Xie W.

J Biol Chem. 2009 Sep 18;284(38):25984-92. doi: 10.1074/jbc.M109.016808. Epub 2009 Jul 17.

10.

Ping-tang Recipe () improves insulin resistance and attenuates hepatic steatosis in high-fat diet-induced obese rats.

Yang SY, Zhao NJ, Li XJ, Zhang HJ, Chen KJ, Li CD.

Chin J Integr Med. 2012 Apr;18(4):262-8. doi: 10.1007/s11655-012-1023-0. Epub 2012 Mar 30.

PMID:
22457136
11.

Glial cell line-derived neurotrophic factor increases beta-cell mass and improves glucose tolerance.

Mwangi S, Anitha M, Mallikarjun C, Ding X, Hara M, Parsadanian A, Larsen CP, Thule P, Sitaraman SV, Anania F, Srinivasan S.

Gastroenterology. 2008 Mar;134(3):727-37. doi: 10.1053/j.gastro.2007.12.033. Epub 2008 Feb 1.

12.

Long-term Fenretinide treatment prevents high-fat diet-induced obesity, insulin resistance, and hepatic steatosis.

Preitner F, Mody N, Graham TE, Peroni OD, Kahn BB.

Am J Physiol Endocrinol Metab. 2009 Dec;297(6):E1420-9. doi: 10.1152/ajpendo.00362.2009. Epub 2009 Oct 13.

13.

Blockade of interleukin 6 signalling ameliorates systemic insulin resistance through upregulation of glucose uptake in skeletal muscle and improves hepatic steatosis in high-fat diet fed mice.

Yamaguchi K, Nishimura T, Ishiba H, Seko Y, Okajima A, Fujii H, Tochiki N, Umemura A, Moriguchi M, Sumida Y, Mitsuyoshi H, Yasui K, Minami M, Okanoue T, Itoh Y.

Liver Int. 2015 Feb;35(2):550-61. doi: 10.1111/liv.12645. Epub 2014 Aug 12.

PMID:
25066281
14.

2,4,6-Trihydroxybenzaldehyde, a potential anti-obesity treatment, suppressed adipocyte differentiation in 3T3-L1 cells and fat accumulation induced by high-fat diet in C57BL/6 mice.

Kim KN, Kang MC, Kang N, Kim SY, Hyun CG, Roh SW, Ko EY, Cho K, Jung WK, Ahn G, Jeon YJ, Kim D.

Environ Toxicol Pharmacol. 2015 Mar;39(2):962-8. doi: 10.1016/j.etap.2015.02.007. Epub 2015 Feb 16.

PMID:
25812771
15.

Methionine restriction prevents the progression of hepatic steatosis in leptin-deficient obese mice.

Malloy VL, Perrone CE, Mattocks DA, Ables GP, Caliendo NS, Orentreich DS, Orentreich N.

Metabolism. 2013 Nov;62(11):1651-61. doi: 10.1016/j.metabol.2013.06.012. Epub 2013 Aug 5.

PMID:
23928105
16.

Macrophage migration inhibitory factor deficiency ameliorates high-fat diet induced insulin resistance in mice with reduced adipose inflammation and hepatic steatosis.

Finucane OM, Reynolds CM, McGillicuddy FC, Harford KA, Morrison M, Baugh J, Roche HM.

PLoS One. 2014 Nov 20;9(11):e113369. doi: 10.1371/journal.pone.0113369. eCollection 2014.

17.

Anti-obesity effects of germinated brown rice extract through down-regulation of lipogenic genes in high fat diet-induced obese mice.

Ho JN, Son ME, Lim WC, Lim ST, Cho HY.

Biosci Biotechnol Biochem. 2012;76(6):1068-74. Epub 2012 Jun 7.

18.

Andrographolide prevents high-fat diet-induced obesity in C57BL/6 mice by suppressing the sterol regulatory element-binding protein pathway.

Ding L, Li J, Song B, Xiao X, Huang W, Zhang B, Tang X, Qi M, Yang Q, Yang Q, Yang L, Wang Z.

J Pharmacol Exp Ther. 2014 Nov;351(2):474-83. doi: 10.1124/jpet.114.217968. Epub 2014 Sep 9.

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