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Results: 1 to 20 of 96

1.

MyD88- and TRIF-independent induction of type I interferon drives naive B cell accumulation but not loss of lymph node architecture in Lyme disease.

Hastey CJ, Ochoa J, Olsen KJ, Barthold SW, Baumgarth N.

Infect Immun. 2014 Apr;82(4):1548-58. doi: 10.1128/IAI.00969-13. Epub 2014 Jan 22.

PMID:
24452685
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Lymphoadenopathy during lyme borreliosis is caused by spirochete migration-induced specific B cell activation.

Tunev SS, Hastey CJ, Hodzic E, Feng S, Barthold SW, Baumgarth N.

PLoS Pathog. 2011 May;7(5):e1002066. doi: 10.1371/journal.ppat.1002066. Epub 2011 May 26.

PMID:
21637808
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Delays and diversions mark the development of B cell responses to Borrelia burgdorferi infection.

Hastey CJ, Elsner RA, Barthold SW, Baumgarth N.

J Immunol. 2012 Jun 1;188(11):5612-22. doi: 10.4049/jimmunol.1103735. Epub 2012 Apr 30.

PMID:
22547698
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

TRIF mediates Toll-like receptor 2-dependent inflammatory responses to Borrelia burgdorferi.

Petnicki-Ocwieja T, Chung E, Acosta DI, Ramos LT, Shin OS, Ghosh S, Kobzik L, Li X, Hu LT.

Infect Immun. 2013 Feb;81(2):402-10. doi: 10.1128/IAI.00890-12. Epub 2012 Nov 19.

PMID:
23166161
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

A critical role for type I IFN in arthritis development following Borrelia burgdorferi infection of mice.

Miller JC, Ma Y, Bian J, Sheehan KC, Zachary JF, Weis JH, Schreiber RD, Weis JJ.

J Immunol. 2008 Dec 15;181(12):8492-503.

PMID:
19050267
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Downstream signals for MyD88-mediated phagocytosis of Borrelia burgdorferi can be initiated by TRIF and are dependent on PI3K.

Shin OS, Miller LS, Modlin RL, Akira S, Uematsu S, Hu LT.

J Immunol. 2009 Jul 1;183(1):491-8. doi: 10.4049/jimmunol.0900724.

PMID:
19542460
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Endothelial cells and fibroblasts amplify the arthritogenic type I IFN response in murine Lyme disease and are major sources of chemokines in Borrelia burgdorferi-infected joint tissue.

Lochhead RB, Sonderegger FL, Ma Y, Brewster JE, Cornwall D, Maylor-Hagen H, Miller JC, Zachary JF, Weis JH, Weis JJ.

J Immunol. 2012 Sep 1;189(5):2488-501. doi: 10.4049/jimmunol.1201095. Epub 2012 Jul 30.

PMID:
22851707
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

The Lyme disease spirochete Borrelia burgdorferi utilizes multiple ligands, including RNA, for interferon regulatory factor 3-dependent induction of type I interferon-responsive genes.

Miller JC, Maylor-Hagen H, Ma Y, Weis JH, Weis JJ.

Infect Immun. 2010 Jul;78(7):3144-53. doi: 10.1128/IAI.01070-09. Epub 2010 Apr 19.

PMID:
20404081
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Improved host defense against septic peritonitis in mice lacking MyD88 and TRIF is linked to a normal interferon response.

Reim D, Rossmann-Bloeck T, Jusek G, Prazeres da Costa O, Holzmann B.

J Leukoc Biol. 2011 Sep;90(3):613-20. doi: 10.1189/jlb.1110602. Epub 2011 May 31.

PMID:
21628330
[PubMed - indexed for MEDLINE]
Free Article
10.

Dual role for Fcγ receptors in host defense and disease in Borrelia burgdorferi-infected mice.

Belperron AA, Liu N, Booth CJ, Bockenstedt LK.

Front Cell Infect Microbiol. 2014 Jun 11;4:75. doi: 10.3389/fcimb.2014.00075. eCollection 2014.

PMID:
24967215
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Myeloid differentiation antigen 88 deficiency impairs pathogen clearance but does not alter inflammation in Borrelia burgdorferi-infected mice.

Liu N, Montgomery RR, Barthold SW, Bockenstedt LK.

Infect Immun. 2004 Jun;72(6):3195-203.

PMID:
15155621
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

MyD88 deficiency results in tissue-specific changes in cytokine induction and inflammation in interleukin-18-independent mice infected with Borrelia burgdorferi.

Behera AK, Hildebrand E, Bronson RT, Perides G, Uematsu S, Akira S, Hu LT.

Infect Immun. 2006 Mar;74(3):1462-70.

PMID:
16495516
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

MyD88 plays a unique role in host defense but not arthritis development in Lyme disease.

Bolz DD, Sundsbak RS, Ma Y, Akira S, Kirschning CJ, Zachary JF, Weis JH, Weis JJ.

J Immunol. 2004 Aug 1;173(3):2003-10.

PMID:
15265935
[PubMed - indexed for MEDLINE]
Free Article
14.

MyD88 and Trif signaling play distinct roles in cardiac dysfunction and mortality during endotoxin shock and polymicrobial sepsis.

Feng Y, Zou L, Zhang M, Li Y, Chen C, Chao W.

Anesthesiology. 2011 Sep;115(3):555-67. doi: 10.1097/ALN.0b013e31822a22f7.

PMID:
21792053
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Neutralization of gamma interferon augments borreliacidal antibody production and severe destructive Lyme arthritis in C3H/HeJ mice.

Munson EL, DeCoster DJ, Nardelli DT, England DM, Callister SM, Schell RF.

Clin Diagn Lab Immunol. 2004 Jan;11(1):35-41.

PMID:
14715542
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Recognition of Borrelia burgdorferi, the Lyme disease spirochete, by TLR7 and TLR9 induces a type I IFN response by human immune cells.

Petzke MM, Brooks A, Krupna MA, Mordue D, Schwartz I.

J Immunol. 2009 Oct 15;183(8):5279-92. doi: 10.4049/jimmunol.0901390. Epub 2009 Sep 30.

PMID:
19794067
[PubMed - indexed for MEDLINE]
Free Article
17.

The loss and gain of marginal zone and peritoneal B cells is different in response to relapsing fever and Lyme disease Borrelia.

Malkiel S, Kuhlow CJ, Mena P, Benach JL.

J Immunol. 2009 Jan 1;182(1):498-506.

PMID:
19109181
[PubMed - indexed for MEDLINE]
Free Article
18.

Identification of a TLR-independent pathway for Borrelia burgdorferi-induced expression of matrix metalloproteinases and inflammatory mediators through binding to integrin alpha 3 beta 1.

Behera AK, Hildebrand E, Uematsu S, Akira S, Coburn J, Hu LT.

J Immunol. 2006 Jul 1;177(1):657-64.

PMID:
16785564
[PubMed - indexed for MEDLINE]
Free Article
19.
20.

Interleukin-23 is required for development of arthritis in mice vaccinated and challenged with Borrelia species.

Kotloski NJ, Nardelli DT, Peterson SH, Torrealba JR, Warner TF, Callister SM, Schell RF.

Clin Vaccine Immunol. 2008 Aug;15(8):1199-207. doi: 10.1128/CVI.00129-08. Epub 2008 Jun 25.

PMID:
18579699
[PubMed - indexed for MEDLINE]
Free PMC Article

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