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Results: 1 to 20 of 94

1.

Targeting PGC-1α to overcome the harmful effects of glucocorticoids in porcine neonatal pancreas cell clusters.

Kim JW, Park SY, You YH, Ham DS, Park HS, Lee SH, Yang HK, Yoon KH.

Transplantation. 2014 Feb 15;97(3):273-9. doi: 10.1097/01.TP.0000438627.68225.25.

PMID:
24448589
[PubMed - indexed for MEDLINE]
2.

Glucocorticoid treatment independently affects expansion and transdifferentiation of porcine neonatal pancreas cell clusters.

Kim JW, Sun C, Jeon SY, You YH, Shin JY, Lee SH, Cho JH, Park CG, Yoon KH.

BMB Rep. 2012 Jan;45(1):51-6.

PMID:
22281014
[PubMed - indexed for MEDLINE]
Free Article
3.

Rapamycin suppresses the expansion and differentiation of porcine neonatal pancreas cell clusters.

Sun CL, Ham DS, Park HS, Kim JW, Cho JH, Song KH, Son HY, Yoon KH.

Transplantation. 2010 Oct 15;90(7):717-24. doi: 10.1097/TP.0b013e3181eceaaf.

PMID:
20622751
[PubMed - indexed for MEDLINE]
4.

Suppression of peroxisome proliferator-activated receptor gamma-coactivator-1alpha normalizes the glucolipotoxicity-induced decreased BETA2/NeuroD gene transcription and improved glucose tolerance in diabetic rats.

Kim JW, You YH, Ham DS, Cho JH, Ko SH, Song KH, Son HY, Suh-Kim H, Lee IK, Yoon KH.

Endocrinology. 2009 Sep;150(9):4074-83. doi: 10.1210/en.2009-0241. Epub 2009 Jun 11.

PMID:
19520786
[PubMed - indexed for MEDLINE]
5.

Dexamethasone suppresses the expansion and transdifferentiation of transplanted porcine neonatal pancreas cell clusters (NPCCs) into beta-cells in normal nude mice.

Ko SH, Kwon HS, Suh SH, Yang JH, Kim SR, Ahn YB, Song KH, Yoo SJ, Son HS, Cha BY, Lee KW, Son HY, Kang SK, Park CG, Yoon KH.

Diabetes Res Clin Pract. 2004 Dec;66 Suppl 1:S97-S101. Erratum in: Diabetes Res Clin Pract. 2005 Aug;69(2):207. Park, JK [corrected to Park, CG].

PMID:
15563989
[PubMed - indexed for MEDLINE]
6.

Fetal PGC-1α overexpression programs adult pancreatic β-cell dysfunction.

Valtat B, Riveline JP, Zhang P, Singh-Estivalet A, Armanet M, Venteclef N, Besseiche A, Kelly DP, Tronche F, Ferré P, Gautier JF, Bréant B, Blondeau B.

Diabetes. 2013 Apr;62(4):1206-16. doi: 10.2337/db12-0314. Epub 2012 Dec 28.

PMID:
23274887
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Dynamic regulation of PDX-1 and FoxO1 expression by FoxA2 in dexamethasone-induced pancreatic β-cells dysfunction.

Chen F, Zhu Y, Tang X, Sun Y, Jia W, Sun Y, Han X.

Endocrinology. 2011 May;152(5):1779-88. doi: 10.1210/en.2010-1048. Epub 2011 Mar 8.

PMID:
21385937
[PubMed - indexed for MEDLINE]
8.

SIRT1 interacts with metabolic transcriptional factors in the pancreas of insulin-resistant and calorie-restricted rats.

Chen YR, Lai YL, Lin SD, Li XT, Fu YC, Xu WC.

Mol Biol Rep. 2013 Apr;40(4):3373-80. doi: 10.1007/s11033-012-2412-3. Epub 2013 Jan 6.

PMID:
23292098
[PubMed - indexed for MEDLINE]
9.

Selenoprotein P expression is controlled through interaction of the coactivator PGC-1alpha with FoxO1a and hepatocyte nuclear factor 4alpha transcription factors.

Speckmann B, Walter PL, Alili L, Reinehr R, Sies H, Klotz LO, Steinbrenner H.

Hepatology. 2008 Dec;48(6):1998-2006. doi: 10.1002/hep.22526.

PMID:
18972406
[PubMed - indexed for MEDLINE]
10.

The interplay of prolactin and the glucocorticoids in the regulation of beta-cell gene expression, fatty acid oxidation, and glucose-stimulated insulin secretion: implications for carbohydrate metabolism in pregnancy.

Arumugam R, Horowitz E, Lu D, Collier JJ, Ronnebaum S, Fleenor D, Freemark M.

Endocrinology. 2008 Nov;149(11):5401-14. doi: 10.1210/en.2008-0051. Epub 2008 Jul 3.

PMID:
18599550
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Energy-sensing factors coactivator peroxisome proliferator-activated receptor γ coactivator 1-α (PGC-1α) and AMP-activated protein kinase control expression of inflammatory mediators in liver: induction of interleukin 1 receptor antagonist.

Buler M, Aatsinki SM, Skoumal R, Komka Z, Tóth M, Kerkelä R, Georgiadi A, Kersten S, Hakkola J.

J Biol Chem. 2012 Jan 13;287(3):1847-60. doi: 10.1074/jbc.M111.302356. Epub 2011 Nov 23.

PMID:
22117073
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Advanced glycation end-products affect transcription factors regulating insulin gene expression.

Puddu A, Storace D, Odetti P, Viviani GL.

Biochem Biophys Res Commun. 2010 Apr 23;395(1):122-5. doi: 10.1016/j.bbrc.2010.03.152. Epub 2010 Mar 29.

PMID:
20353756
[PubMed - indexed for MEDLINE]
13.

ALAS1 gene expression is down-regulated by Akt-mediated phosphorylation and nuclear exclusion of FOXO1 by vanadate in diabetic mice.

Oliveri LM, Davio C, Batlle AM, Gerez EN.

Biochem J. 2012 Mar 1;442(2):303-10. doi: 10.1042/BJ20111005.

PMID:
22070747
[PubMed - indexed for MEDLINE]
Free Article
14.

Adenoviruses Expressing PDX-1, BETA2/NeuroD and MafA Induces the Transdifferentiation of Porcine Neonatal Pancreas Cell Clusters and Adult Pig Pancreatic Cells into Beta-Cells.

You YH, Ham DS, Park HS, Rhee M, Kim JW, Yoon KH.

Diabetes Metab J. 2011 Apr;35(2):119-29. doi: 10.4093/dmj.2011.35.2.119. Epub 2011 Apr 30.

PMID:
21738894
[PubMed]
Free PMC Article
15.

Differentiation of human adipose tissue-derived stem cells into aggregates of insulin-producing cells through the overexpression of pancreatic and duodenal homeobox gene-1.

Lee J, Kim SC, Kim SJ, Lee H, Jung EJ, Jung SH, Han DJ.

Cell Transplant. 2013;22(6):1053-60. doi: 10.3727/096368912X657215. Epub 2012 Oct 1.

PMID:
23031216
[PubMed - indexed for MEDLINE]
16.

Transcriptional co-activator peroxisome proliferator-activated receptor (PPAR)gamma co-activator-1beta is involved in the regulation of glucose-stimulated insulin secretion in INS-1E cells.

Oberkofler H, Hafner M, Felder T, Krempler F, Patsch W.

J Mol Med (Berl). 2009 Mar;87(3):299-306. doi: 10.1007/s00109-008-0425-0. Epub 2008 Dec 11.

PMID:
19082571
[PubMed - indexed for MEDLINE]
17.
18.

PDX-1 functions as a master factor in the pancreas.

Kaneto H, Matsuoka TA, Miyatsuka T, Kawamori D, Katakami N, Yamasaki Y, Matsuhisa M.

Front Biosci. 2008 May 1;13:6406-20. Review.

PMID:
18508668
[PubMed - indexed for MEDLINE]
19.

Profound defects in pancreatic beta-cell function in mice with combined heterozygous mutations in Pdx-1, Hnf-1alpha, and Hnf-3beta.

Shih DQ, Heimesaat M, Kuwajima S, Stein R, Wright CV, Stoffel M.

Proc Natl Acad Sci U S A. 2002 Mar 19;99(6):3818-23.

PMID:
11904435
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

The forkhead transcription factor Foxo1 bridges the JNK pathway and the transcription factor PDX-1 through its intracellular translocation.

Kawamori D, Kaneto H, Nakatani Y, Matsuoka TA, Matsuhisa M, Hori M, Yamasaki Y.

J Biol Chem. 2006 Jan 13;281(2):1091-8. Epub 2005 Nov 9.

PMID:
16282329
[PubMed - indexed for MEDLINE]
Free Article

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