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Items: 1 to 20 of 136

1.

Microglial dysfunction in brain aging and Alzheimer's disease.

Mosher KI, Wyss-Coray T.

Biochem Pharmacol. 2014 Apr 15;88(4):594-604. doi: 10.1016/j.bcp.2014.01.008. Epub 2014 Jan 18. Review.

2.

Dystrophic (senescent) rather than activated microglial cells are associated with tau pathology and likely precede neurodegeneration in Alzheimer's disease.

Streit WJ, Braak H, Xue QS, Bechmann I.

Acta Neuropathol. 2009 Oct;118(4):475-85. doi: 10.1007/s00401-009-0556-6. Epub 2009 Jun 10.

3.

Microglial dysfunction and defective beta-amyloid clearance pathways in aging Alzheimer's disease mice.

Hickman SE, Allison EK, El Khoury J.

J Neurosci. 2008 Aug 13;28(33):8354-60. doi: 10.1523/JNEUROSCI.0616-08.2008.

4.

Microglia and inflammation in Alzheimer's disease.

Mandrekar-Colucci S, Landreth GE.

CNS Neurol Disord Drug Targets. 2010 Apr;9(2):156-67. Review.

5.

Microglial activation induced by factor(s) contained in sera from Alzheimer-related ApoE genotypes.

Lombardi VR, García M, Cacabelos R.

J Neurosci Res. 1998 Nov 15;54(4):539-53.

PMID:
9822164
6.

Cerebrospinal fluid microglial antibodies: potential diagnostic markers for immune mechanisms in Alzheimer's disease.

McRae A, Dahlström A, Polinsky R, Ling EA.

Behav Brain Res. 1993 Nov 30;57(2):225-34. Review.

PMID:
8117427
7.

TLR4 mutation reduces microglial activation, increases Aβ deposits and exacerbates cognitive deficits in a mouse model of Alzheimer's disease.

Song M, Jin J, Lim JE, Kou J, Pattanayak A, Rehman JA, Kim HD, Tahara K, Lalonde R, Fukuchi K.

J Neuroinflammation. 2011 Aug 9;8:92. doi: 10.1186/1742-2094-8-92.

8.

Microglia as a critical player in both developmental and late-life CNS pathologies.

Derecki NC, Katzmarski N, Kipnis J, Meyer-Luehmann M.

Acta Neuropathol. 2014 Sep;128(3):333-45. doi: 10.1007/s00401-014-1321-z. Epub 2014 Jul 24. Review.

9.

Microglia and Alzheimer's disease pathogenesis.

Streit WJ.

J Neurosci Res. 2004 Jul 1;77(1):1-8. Review.

PMID:
15197750
10.

The role of microglial cellular senescence in the aging and Alzheimer diseased brain.

Flanary B.

Rejuvenation Res. 2005 Summer;8(2):82-5. Review.

PMID:
15929715
11.

Microglial dystrophy in the aged and Alzheimer's disease brain is associated with ferritin immunoreactivity.

Lopes KO, Sparks DL, Streit WJ.

Glia. 2008 Aug 1;56(10):1048-60. doi: 10.1002/glia.20678.

PMID:
18442088
12.

Microglial pathology.

Streit WJ, Xue QS, Tischer J, Bechmann I.

Acta Neuropathol Commun. 2014 Sep 26;2:142. doi: 10.1186/s40478-014-0142-6. Review.

13.

Modeling microglial activation in Alzheimer's disease with human postmortem microglial cultures.

Lue LF, Walker DG, Rogers J.

Neurobiol Aging. 2001 Nov-Dec;22(6):945-56. Review.

PMID:
11755003
14.

Manipulation of microglial activation as a therapeutic strategy in Alzheimer's disease.

Shie FS, Woltjer RL.

Curr Med Chem. 2007;14(27):2865-71. Review.

PMID:
18045132
15.

Life and death of microglia.

Streit WJ, Xue QS.

J Neuroimmune Pharmacol. 2009 Dec;4(4):371-9. doi: 10.1007/s11481-009-9163-5. Epub 2009 Aug 14. Review.

PMID:
19680817
16.

How chronic inflammation can affect the brain and support the development of Alzheimer's disease in old age: the role of microglia and astrocytes.

Blasko I, Stampfer-Kountchev M, Robatscher P, Veerhuis R, Eikelenboom P, Grubeck-Loebenstein B.

Aging Cell. 2004 Aug;3(4):169-76. Review.

17.

Microglia actions in Alzheimer’s disease.

Prokop S, Miller KR, Heppner FL.

Acta Neuropathol. 2013 Oct;126(4):461-77. Review.

PMID:
24224195
18.

Harnessing the power of gene microarrays for the study of brain aging and Alzheimer's disease: statistical reliability and functional correlation.

Blalock EM, Chen KC, Stromberg AJ, Norris CM, Kadish I, Kraner SD, Porter NM, Landfield PW.

Ageing Res Rev. 2005 Nov;4(4):481-512. Epub 2005 Oct 27. Review.

PMID:
16257272
19.

Ex vivo cultures of microglia from young and aged rodent brain reveal age-related changes in microglial function.

Njie EG, Boelen E, Stassen FR, Steinbusch HW, Borchelt DR, Streit WJ.

Neurobiol Aging. 2012 Jan;33(1):195.e1-12. doi: 10.1016/j.neurobiolaging.2010.05.008. Epub 2010 Jul 2.

20.

Accelerated microglial pathology is associated with Aβ plaques in mouse models of Alzheimer's disease.

Baron R, Babcock AA, Nemirovsky A, Finsen B, Monsonego A.

Aging Cell. 2014 Aug;13(4):584-95. doi: 10.1111/acel.12210. Epub 2014 Mar 18.

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