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Results: 1 to 20 of 107

1.

Hyperleucinemia causes hippocampal retromer deficiency linking diabetes to Alzheimer's disease.

Morabito MV, Berman DE, Schneider RT, Zhang Y, Leibel RL, Small SA.

Neurobiol Dis. 2014 May;65:188-92. doi: 10.1016/j.nbd.2013.12.017. Epub 2014 Jan 14.

PMID:
24440570
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Diabetes-associated SorCS1 regulates Alzheimer's amyloid-beta metabolism: evidence for involvement of SorL1 and the retromer complex.

Lane RF, Raines SM, Steele JW, Ehrlich ME, Lah JA, Small SA, Tanzi RE, Attie AD, Gandy S.

J Neurosci. 2010 Sep 29;30(39):13110-5. doi: 10.1523/JNEUROSCI.3872-10.2010.

PMID:
20881129
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Retromer deficiency observed in Alzheimer's disease causes hippocampal dysfunction, neurodegeneration, and Abeta accumulation.

Muhammad A, Flores I, Zhang H, Yu R, Staniszewski A, Planel E, Herman M, Ho L, Kreber R, Honig LS, Ganetzky B, Duff K, Arancio O, Small SA.

Proc Natl Acad Sci U S A. 2008 May 20;105(20):7327-32. doi: 10.1073/pnas.0802545105. Epub 2008 May 14.

PMID:
18480253
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

The location and trafficking routes of the neuronal retromer and its role in amyloid precursor protein transport.

Bhalla A, Vetanovetz CP, Morel E, Chamoun Z, Di Paolo G, Small SA.

Neurobiol Dis. 2012 Jul;47(1):126-34. doi: 10.1016/j.nbd.2012.03.030. Epub 2012 Apr 6.

PMID:
22516235
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Increased Aβ production prompts the onset of glucose intolerance and insulin resistance.

Jiménez-Palomares M, Ramos-Rodríguez JJ, López-Acosta JF, Pacheco-Herrero M, Lechuga-Sancho AM, Perdomo G, García-Alloza M, Cózar-Castellano I.

Am J Physiol Endocrinol Metab. 2012 Jun 1;302(11):E1373-80. doi: 10.1152/ajpendo.00500.2011. Epub 2012 Mar 13.

PMID:
22414803
[PubMed - indexed for MEDLINE]
Free Article
6.

Early alterations in energy metabolism in the hippocampus of APPswe/PS1dE9 mouse model of Alzheimer's disease.

Pedrós I, Petrov D, Allgaier M, Sureda F, Barroso E, Beas-Zarate C, Auladell C, Pallàs M, Vázquez-Carrera M, Casadesús G, Folch J, Camins A.

Biochim Biophys Acta. 2014 Sep;1842(9):1556-66. doi: 10.1016/j.bbadis.2014.05.025. Epub 2014 Jun 2.

PMID:
24887203
[PubMed - indexed for MEDLINE]
7.

VPS35 haploinsufficiency increases Alzheimer's disease neuropathology.

Wen L, Tang FL, Hong Y, Luo SW, Wang CL, He W, Shen C, Jung JU, Xiong F, Lee DH, Zhang QG, Brann D, Kim TW, Yan R, Mei L, Xiong WC.

J Cell Biol. 2011 Nov 28;195(5):765-79. doi: 10.1083/jcb.201105109. Epub 2011 Nov 21.

PMID:
22105352
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Retromer disruption promotes amyloidogenic APP processing.

Sullivan CP, Jay AG, Stack EC, Pakaluk M, Wadlinger E, Fine RE, Wells JM, Morin PJ.

Neurobiol Dis. 2011 Aug;43(2):338-45. doi: 10.1016/j.nbd.2011.04.002. Epub 2011 Apr 16.

PMID:
21515373
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Metformin attenuates Alzheimer's disease-like neuropathology in obese, leptin-resistant mice.

Li J, Deng J, Sheng W, Zuo Z.

Pharmacol Biochem Behav. 2012 Jun;101(4):564-74. doi: 10.1016/j.pbb.2012.03.002. Epub 2012 Mar 9.

PMID:
22425595
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Impaired Src signaling and post-synaptic actin polymerization in Alzheimer's disease mice hippocampus--linking NMDA receptors and the reelin pathway.

Mota SI, Ferreira IL, Valero J, Ferreiro E, Carvalho AL, Oliveira CR, Rego AC.

Exp Neurol. 2014 Nov;261:698-709. doi: 10.1016/j.expneurol.2014.07.023. Epub 2014 Aug 13.

PMID:
25128699
[PubMed - indexed for MEDLINE]
11.

Limited Alzheimer-type neurodegeneration in experimental obesity and type 2 diabetes mellitus.

Moroz N, Tong M, Longato L, Xu H, de la Monte SM.

J Alzheimers Dis. 2008 Sep;15(1):29-44.

PMID:
18780965
[PubMed - indexed for MEDLINE]
12.

Omega-3 fatty acid docosahexaenoic acid increases SorLA/LR11, a sorting protein with reduced expression in sporadic Alzheimer's disease (AD): relevance to AD prevention.

Ma QL, Teter B, Ubeda OJ, Morihara T, Dhoot D, Nyby MD, Tuck ML, Frautschy SA, Cole GM.

J Neurosci. 2007 Dec 26;27(52):14299-307.

PMID:
18160637
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Amyloid-beta peptides stimulate the expression of the p75(NTR) neurotrophin receptor in SHSY5Y human neuroblastoma cells and AD transgenic mice.

Chakravarthy B, Gaudet C, Ménard M, Atkinson T, Brown L, Laferla FM, Armato U, Whitfield J.

J Alzheimers Dis. 2010;19(3):915-25. doi: 10.3233/JAD-2010-1288.

PMID:
20157247
[PubMed - indexed for MEDLINE]
14.

Phytic acid as a potential treatment for alzheimer's pathology: evidence from animal and in vitro models.

Anekonda TS, Wadsworth TL, Sabin R, Frahler K, Harris C, Petriko B, Ralle M, Woltjer R, Quinn JF.

J Alzheimers Dis. 2011;23(1):21-35. doi: 10.3233/JAD-2010-101287.

PMID:
20930278
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Implication of mouse Vps26b-Vps29-Vps35 retromer complex in sortilin trafficking.

Kim E, Lee Y, Lee HJ, Kim JS, Song BS, Huh JW, Lee SR, Kim SU, Kim SH, Hong Y, Shim I, Chang KT.

Biochem Biophys Res Commun. 2010 Dec 10;403(2):167-71. doi: 10.1016/j.bbrc.2010.10.121. Epub 2010 Oct 30.

PMID:
21040701
[PubMed - indexed for MEDLINE]
16.

Connective tissue growth factor (CTGF) expression in the brain is a downstream effector of insulin resistance- associated promotion of Alzheimer's disease beta-amyloid neuropathology.

Zhao Z, Ho L, Wang J, Qin W, Festa ED, Mobbs C, Hof P, Rocher A, Masur S, Haroutunian V, Pasinetti GM.

FASEB J. 2005 Dec;19(14):2081-2. Epub 2005 Sep 26.

PMID:
16186174
[PubMed - indexed for MEDLINE]
Free Article
17.

High-fat diet increases tau expression in the brain of T2DM and AD mice independently of peripheral metabolic status.

Takalo M, Haapasalo A, Martiskainen H, Kurkinen KM, Koivisto H, Miettinen P, Khandelwal VK, Kemppainen S, Kaminska D, Mäkinen P, Leinonen V, Pihlajamäki J, Soininen H, Laakso M, Tanila H, Hiltunen M.

J Nutr Biochem. 2014 Jun;25(6):634-41. doi: 10.1016/j.jnutbio.2014.02.003. Epub 2014 Mar 12.

PMID:
24746833
[PubMed - indexed for MEDLINE]
18.

An anti-diabetes agent protects the mouse brain from defective insulin signaling caused by Alzheimer's disease- associated Aβ oligomers.

Bomfim TR, Forny-Germano L, Sathler LB, Brito-Moreira J, Houzel JC, Decker H, Silverman MA, Kazi H, Melo HM, McClean PL, Holscher C, Arnold SE, Talbot K, Klein WL, Munoz DP, Ferreira ST, De Felice FG.

J Clin Invest. 2012 Apr 2;122(4):1339-53. doi: 10.1172/JCI57256.

PMID:
22476196
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Increased food intake leads to obesity and insulin resistance in the tg2576 Alzheimer's disease mouse model.

Kohjima M, Sun Y, Chan L.

Endocrinology. 2010 Apr;151(4):1532-40. doi: 10.1210/en.2009-1196. Epub 2010 Feb 22.

PMID:
20176720
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

A diet high in omega-3 fatty acids does not improve or protect cognitive performance in Alzheimer's transgenic mice.

Arendash GW, Jensen MT, Salem N Jr, Hussein N, Cracchiolo J, Dickson A, Leighty R, Potter H.

Neuroscience. 2007 Oct 26;149(2):286-302. Epub 2007 Aug 14.

PMID:
17904756
[PubMed - indexed for MEDLINE]

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