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Multicentre surveillance of prevalence of the 23S rRNA A2058G and A2059G point mutations and molecular subtypes of Treponema pallidum in Taiwan, 2009-2013.

Wu BR, Yang CJ, Tsai MS, Lee KY, Lee NY, Huang WC, Wu H, Lee CH, Chen TC, Ko WC, Lin HH, Lu PL, Chen YH, Liu WC, Yang SP, Wu PY, Su YC, Hung CC, Chang SY.

Clin Microbiol Infect. 2014 Aug;20(8):802-7. doi: 10.1111/1469-0691.12529. Epub 2014 Feb 13.


Evaluation of macrolide resistance and enhanced molecular typing of Treponema pallidum in patients with syphilis in Taiwan: a prospective multicenter study.

Wu H, Chang SY, Lee NY, Huang WC, Wu BR, Yang CJ, Liang SH, Lee CH, Ko WC, Lin HH, Chen YH, Liu WC, Su YC, Hsieh CY, Wu PY, Hung CC.

J Clin Microbiol. 2012 Jul;50(7):2299-304. doi: 10.1128/JCM.00341-12. Epub 2012 Apr 18.


Macrolide resistance testing and molecular subtyping of Treponema pallidum strains from southern Africa.

Müller EE, Paz-Bailey G, Lewis DA.

Sex Transm Infect. 2012 Oct;88(6):470-4. Epub 2012 May 18.


Detection of the A2058G and A2059G 23S rRNA gene point mutations associated with azithromycin resistance in Treponema pallidum by use of a TaqMan real-time multiplex PCR assay.

Chen CY, Chi KH, Pillay A, Nachamkin E, Su JR, Ballard RC.

J Clin Microbiol. 2013 Mar;51(3):908-13. doi: 10.1128/JCM.02770-12. Epub 2013 Jan 2.


Macrolide resistance and molecular types of Treponema pallidum causing primary syphilis in Shanghai, China.

Martin IE, Gu W, Yang Y, Tsang RS.

Clin Infect Dis. 2009 Aug 15;49(4):515-21. doi: 10.1086/600878.


Jarisch-Herxheimer reaction among HIV-positive patients with early syphilis: azithromycin versus benzathine penicillin G therapy.

Tsai MS, Yang CJ, Lee NY, Hsieh SM, Lin YH, Sun HY, Sheng WH, Lee KY, Yang SP, Liu WC, Wu PY, Ko WC, Hung CC.

J Int AIDS Soc. 2014 Aug 28;17:18993. doi: 10.7448/IAS.17.1.18993. eCollection 2014.


Macrolide treatment failure in a case of secondary syphilis: a novel A2059G mutation in the 23S rRNA gene of Treponema pallidum subsp. pallidum.

Matejková P, Flasarová M, Zákoucká H, Borek M, Kremenová S, Arenberger P, Woznicová V, Weinstock GM, Smajs D.

J Med Microbiol. 2009 Jun;58(Pt 6):832-6. doi: 10.1099/jmm.0.007542-0.


High prevalence of macrolide resistant Treponema pallidum strains in a London centre.

Tipple C, McClure MO, Taylor GP.

Sex Transm Infect. 2011 Oct;87(6):486-8. doi: 10.1136/sextrans-2011-050082.


Two mutations associated with macrolide resistance in Treponema pallidum: increasing prevalence and correlation with molecular strain type in Seattle, Washington.

Grimes M, Sahi SK, Godornes BC, Tantalo LC, Roberts N, Bostick D, Marra CM, Lukehart SA.

Sex Transm Dis. 2012 Dec;39(12):954-8. doi: 10.1097/OLQ.0b013e31826ae7a8.


Sequencing-based molecular typing of treponema pallidum strains in the Czech Republic: all identified genotypes are related to the sequence of the SS14 strain.

Flasarová M, Pospíšilová P, Mikalová L, Vališová Z, Dastychová E, Strnadel R, Kuklová I, Woznicová V, Zákoucká H, Šmajs D.

Acta Derm Venereol. 2012 Nov;92(6):669-74. doi: 10.2340/00015555-1335.


High prevalence of azithromycin resistance to Treponema pallidum in geographically different areas in China.

Chen XS, Yin YP, Wei WH, Wang HC, Peng RR, Zheng HP, Zhang JP, Zhu BY, Liu QZ, Huang SJ.

Clin Microbiol Infect. 2013 Oct;19(10):975-9. doi: 10.1111/1469-0691.12098. Epub 2012 Dec 10.


Evaluation of azithromycin resistance in Treponema pallidum specimens from Madagascar.

Van Damme K, Behets F, Ravelomanana N, Godornes C, Khan M, Randrianasolo B, Rabenja NL, Lukehart S, Cohen M, Hook E.

Sex Transm Dis. 2009 Dec;36(12):775-6. doi: 10.1097/OLQ.0b013e3181bd11dd.


Two mutations associated with macrolide resistance in Treponema pallidum in Shandong, China.

Li Z, Hou J, Zheng R, Li Z, Wen J, Liu D, Liu R, Chu T, Liu B, Yu G, Tian H, Zhang F.

J Clin Microbiol. 2013 Dec;51(12):4270-1. doi: 10.1128/JCM.01261-13. Epub 2013 Sep 18. No abstract available.


Azithromycin-resistant syphilis-causing strains in Sydney, Australia: prevalence and risk factors.

Read P, Jeoffreys N, Tagg K, Guy RJ, Gilbert GL, Donovan B.

J Clin Microbiol. 2014 Aug;52(8):2776-81. doi: 10.1128/JCM.00301-14. Epub 2014 May 21.


Antibiotic selection may contribute to increases in macrolide-resistant Treponema pallidum.

Marra CM, Colina AP, Godornes C, Tantalo LC, Puray M, Centurion-Lara A, Lukehart SA.

J Infect Dis. 2006 Dec 15;194(12):1771-3. Epub 2006 Nov 3.


Comparison of CDC and sequence-based molecular typing of syphilis treponemes: tpr and arp loci are variable in multiple samples from the same patient.

Mikalová L, Pospíšilová P, Woznicová V, Kuklová I, Zákoucká H, Smajs D.

BMC Microbiol. 2013 Jul 30;13:178. doi: 10.1186/1471-2180-13-178.


Treponema pallidum azithromycin resistance in Dublin, Ireland.

Muldoon EG, Walsh A, Crowley B, Mulcahy F.

Sex Transm Dis. 2012 Oct;39(10):784-6.


Azithromycin resistance in Treponema pallidum.

Katz KA, Klausner JD.

Curr Opin Infect Dis. 2008 Feb;21(1):83-91. doi: 10.1097/QCO.0b013e3282f44772. Review.

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