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Results: 1 to 20 of 97

1.

Notoginsenoside R1-mediated neuroprotection involves estrogen receptor-dependent crosstalk between Akt and ERK1/2 pathways: a novel mechanism of Nrf2/ARE signaling activation.

Meng X, Sun G, Ye J, Xu H, Wang H, Sun X.

Free Radic Res. 2014 Apr;48(4):445-60. doi: 10.3109/10715762.2014.885117. Epub 2014 Feb 17.

PMID:
24437944
[PubMed - in process]
2.

Suppression of NADPH oxidase- and mitochondrion-derived superoxide by Notoginsenoside R1 protects against cerebral ischemia-reperfusion injury through estrogen receptor-dependent activation of Akt/Nrf2 pathways.

Meng X, Wang M, Wang X, Sun G, Ye J, Xu H, Sun X.

Free Radic Res. 2014 Jul;48(7):823-38. doi: 10.3109/10715762.2014.911853. Epub 2014 May 7.

PMID:
24720662
[PubMed - in process]
3.

P90RSK and Nrf2 Activation via MEK1/2-ERK1/2 Pathways Mediated by Notoginsenoside R2 to Prevent 6-Hydroxydopamine-Induced Apoptotic Death in SH-SY5Y Cells.

Meng XB, Sun GB, Wang M, Sun J, Qin M, Sun XB.

Evid Based Complement Alternat Med. 2013;2013:971712. doi: 10.1155/2013/971712. Epub 2013 Sep 18.

PMID:
24159358
[PubMed]
Free PMC Article
4.

Attenuation of Aβ25-35-induced parallel autophagic and apoptotic cell death by gypenoside XVII through the estrogen receptor-dependent activation of Nrf2/ARE pathways.

Meng X, Wang M, Sun G, Ye J, Zhou Y, Dong X, Wang T, Lu S, Sun X.

Toxicol Appl Pharmacol. 2014 Aug 15;279(1):63-75. doi: 10.1016/j.taap.2014.03.026. Epub 2014 Apr 12.

PMID:
24726523
[PubMed - in process]
5.

Up-regulation of Nrf2-mediated heme oxygenase-1 expression by eckol, a phlorotannin compound, through activation of Erk and PI3K/Akt.

Kim KC, Kang KA, Zhang R, Piao MJ, Kim GY, Kang MY, Lee SJ, Lee NH, Surh YJ, Hyun JW.

Int J Biochem Cell Biol. 2010 Feb;42(2):297-305. doi: 10.1016/j.biocel.2009.11.009. Epub 2009 Nov 18.

PMID:
19931411
[PubMed - indexed for MEDLINE]
6.

15-Deoxy-Delta(12,14)-prostaglandin J(2) rescues PC12 cells from H2O2-induced apoptosis through Nrf2-mediated upregulation of heme oxygenase-1: potential roles of Akt and ERK1/2.

Kim JW, Li MH, Jang JH, Na HK, Song NY, Lee C, Johnson JA, Surh YJ.

Biochem Pharmacol. 2008 Dec 1;76(11):1577-89. doi: 10.1016/j.bcp.2008.08.007. Epub 2008 Aug 19.

PMID:
18775681
[PubMed - indexed for MEDLINE]
7.

A formulated red ginseng extract rescues PC12 cells from PCB-induced oxidative cell death through Nrf2-mediated upregulation of heme oxygenase-1 and glutamate cysteine ligase.

Park SH, Jang JH, Chen CY, Na HK, Surh YJ.

Toxicology. 2010 Nov 28;278(1):131-9. doi: 10.1016/j.tox.2010.04.003. Epub 2010 Apr 22.

PMID:
20399244
[PubMed - indexed for MEDLINE]
8.

Mechanism of phytoestrogen puerarin-mediated cytoprotection following oxidative injury: estrogen receptor-dependent up-regulation of PI3K/Akt and HO-1.

Hwang YP, Jeong HG.

Toxicol Appl Pharmacol. 2008 Dec 15;233(3):371-81. doi: 10.1016/j.taap.2008.09.006. Epub 2008 Sep 19.

PMID:
18845176
[PubMed - indexed for MEDLINE]
9.

PM2.5 induces Nrf2-mediated defense mechanisms against oxidative stress by activating PIK3/AKT signaling pathway in human lung alveolar epithelial A549 cells.

Deng X, Rui W, Zhang F, Ding W.

Cell Biol Toxicol. 2013 Jun;29(3):143-57. doi: 10.1007/s10565-013-9242-5. Epub 2013 Mar 24.

PMID:
23525690
[PubMed - indexed for MEDLINE]
10.

Ginsenoside Rb1 protects against 6-hydroxydopamine-induced oxidative stress by increasing heme oxygenase-1 expression through an estrogen receptor-related PI3K/Akt/Nrf2-dependent pathway in human dopaminergic cells.

Hwang YP, Jeong HG.

Toxicol Appl Pharmacol. 2010 Jan 1;242(1):18-28. doi: 10.1016/j.taap.2009.09.009. Epub 2009 Sep 23.

PMID:
19781563
[PubMed - indexed for MEDLINE]
11.

Deprenyl prevents MPP(+)-induced oxidative damage in PC12 cells by the upregulation of Nrf2-mediated NQO1 expression through the activation of PI3K/Akt and Erk.

Xiao H, Lv F, Xu W, Zhang L, Jing P, Cao X.

Toxicology. 2011 Dec 18;290(2-3):286-94. doi: 10.1016/j.tox.2011.10.007. Epub 2011 Oct 15.

PMID:
22019741
[PubMed - indexed for MEDLINE]
12.

Baicalein protects against 6-OHDA-induced neurotoxicity through activation of Keap1/Nrf2/HO-1 and involving PKCα and PI3K/AKT signaling pathways.

Zhang Z, Cui W, Li G, Yuan S, Xu D, Hoi MP, Lin Z, Dou J, Han Y, Lee SM.

J Agric Food Chem. 2012 Aug 22;60(33):8171-82. doi: 10.1021/jf301511m. Epub 2012 Aug 9.

PMID:
22838648
[PubMed - indexed for MEDLINE]
13.

Hyperoxia stimulates an Nrf2-ARE transcriptional response via ROS-EGFR-PI3K-Akt/ERK MAP kinase signaling in pulmonary epithelial cells.

Papaiahgari S, Zhang Q, Kleeberger SR, Cho HY, Reddy SP.

Antioxid Redox Signal. 2006 Jan-Feb;8(1-2):43-52.

PMID:
16487036
[PubMed - indexed for MEDLINE]
14.

Docosahexaenoic acid inhibition of inflammation is partially via cross-talk between Nrf2/heme oxygenase 1 and IKK/NF-κB pathways.

Yang YC, Lii CK, Wei YL, Li CC, Lu CY, Liu KL, Chen HW.

J Nutr Biochem. 2013 Jan;24(1):204-12. doi: 10.1016/j.jnutbio.2012.05.003. Epub 2012 Aug 15.

PMID:
22901690
[PubMed - indexed for MEDLINE]
15.

4-Ketopinoresinol, a novel naturally occurring ARE activator, induces the Nrf2/HO-1 axis and protects against oxidative stress-induced cell injury via activation of PI3K/AKT signaling.

Chen HH, Chen YT, Huang YW, Tsai HJ, Kuo CC.

Free Radic Biol Med. 2012 Mar 15;52(6):1054-66. doi: 10.1016/j.freeradbiomed.2011.12.012. Epub 2011 Dec 24.

PMID:
22245092
[PubMed - indexed for MEDLINE]
16.

Carvedilol Attenuates 6-Hydroxydopamine-Induced Cell Death in PC12 Cells: Involvement of Akt and Nrf2/ARE Pathways.

Wang L, Wang R, Jin M, Huang Y, Liu A, Qin J, Chen M, Wen S, Pi R, Shen W.

Neurochem Res. 2014 Jun 21. [Epub ahead of print]

PMID:
24952068
[PubMed - as supplied by publisher]
17.

Ginsenoside Rb1 Prevents MPP(+)-Induced Apoptosis in PC12 Cells by Stimulating Estrogen Receptors with Consequent Activation of ERK1/2, Akt and Inhibition of SAPK/JNK, p38 MAPK.

Hashimoto R, Yu J, Koizumi H, Ouchi Y, Okabe T.

Evid Based Complement Alternat Med. 2012;2012:693717. Epub 2012 Sep 16.

PMID:
23024694
[PubMed]
Free PMC Article
18.

7,8-Dihydroxyflavone protects human keratinocytes against oxidative stress-induced cell damage via the ERK and PI3K/Akt-mediated Nrf2/HO-1 signaling pathways.

Ryu MJ, Kang KA, Piao MJ, Kim KC, Zheng J, Yao CW, Cha JW, Chung HS, Kim SC, Jung E, Park D, Chae S, Hyun JW.

Int J Mol Med. 2014 Apr;33(4):964-70. doi: 10.3892/ijmm.2014.1643. Epub 2014 Feb 4.

PMID:
24503931
[PubMed - in process]
19.

1,2,3,4,6-penta-O-galloyl-β-D-glucose protects PC12 Cells from MPP(+)-mediated cell death by inducing heme oxygenase-1 in an ERK- and Akt-dependent manner.

Chen H, Li H, Cao F, Zhen L, Bai J, Yuan S, Mei Y.

J Huazhong Univ Sci Technolog Med Sci. 2012 Oct;32(5):737-45. doi: 10.1007/s11596-012-1027-1. Epub 2012 Oct 18.

PMID:
23073806
[PubMed - in process]
20.

Berberine, a natural antidiabetes drug, attenuates glucose neurotoxicity and promotes Nrf2-related neurite outgrowth.

Hsu YY, Tseng YT, Lo YC.

Toxicol Appl Pharmacol. 2013 Nov 1;272(3):787-96. doi: 10.1016/j.taap.2013.08.008. Epub 2013 Aug 15.

PMID:
23954465
[PubMed - indexed for MEDLINE]

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