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Results: 1 to 20 of 100

1.

Genomic analysis of head and neck squamous cell carcinoma cell lines and human tumors: a rational approach to preclinical model selection.

Li H, Wawrose JS, Gooding WE, Garraway LA, Lui VW, Peyser ND, Grandis JR.

Mol Cancer Res. 2014 Apr;12(4):571-82. doi: 10.1158/1541-7786.MCR-13-0396. Epub 2014 Jan 14.

PMID:
24425785
[PubMed - in process]
2.

Oncogenic mutations of the PIK3CA gene in head and neck squamous cell carcinomas.

Murugan AK, Hong NT, Fukui Y, Munirajan AK, Tsuchida N.

Int J Oncol. 2008 Jan;32(1):101-11.

PMID:
18097548
[PubMed - indexed for MEDLINE]
3.

Frequent mutation of the PI3K pathway in head and neck cancer defines predictive biomarkers.

Lui VW, Hedberg ML, Li H, Vangara BS, Pendleton K, Zeng Y, Lu Y, Zhang Q, Du Y, Gilbert BR, Freilino M, Sauerwein S, Peyser ND, Xiao D, Diergaarde B, Wang L, Chiosea S, Seethala R, Johnson JT, Kim S, Duvvuri U, Ferris RL, Romkes M, Nukui T, Kwok-Shing Ng P, Garraway LA, Hammerman PS, Mills GB, Grandis JR.

Cancer Discov. 2013 Jul;3(7):761-9. doi: 10.1158/2159-8290.CD-13-0103. Epub 2013 Apr 25.

PMID:
23619167
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Frequent mutations in TP53 and CDKN2A found by next-generation sequencing of head and neck cancer cell lines.

Nichols AC, Yoo J, Palma DA, Fung K, Franklin JH, Koropatnick J, Mymryk JS, Batada NN, Barrett JW.

Arch Otolaryngol Head Neck Surg. 2012 Aug;138(8):732-9. doi: 10.1001/archoto.2012.1558.

PMID:
22911296
[PubMed - indexed for MEDLINE]
5.

Integrative and comparative genomic analysis of HPV-positive and HPV-negative head and neck squamous cell carcinomas.

Seiwert TY, Zuo Z, Keck MK, Khattri A, Pedamallu CS, Stricker TP, Brown CD, Pugh TJ, Stojanov P, Cho J, Lawrence M, Getz G, Bragelmann J, DeBoer R, Weichselbaum RR, Langerman A, Portugal LD, Blair EA, Stenson KM, Lingen MW, Cohen EE, Vokes EE, White KP, Hammerman PS.

Clin Cancer Res. 2014 Jul 23. pii: clincanres.3310.2013. [Epub ahead of print]

PMID:
25056374
[PubMed - as supplied by publisher]
6.

A patient tumor transplant model of squamous cell cancer identifies PI3K inhibitors as candidate therapeutics in defined molecular bins.

Keysar SB, Astling DP, Anderson RT, Vogler BW, Bowles DW, Morton JJ, Paylor JJ, Glogowska MJ, Le PN, Eagles-Soukup JR, Kako SL, Takimoto SM, Sehrt DB, Umpierrez A, Pittman MA, Macfadden SM, Helber RM, Peterson S, Hausman DF, Said S, Leem TH, Goddard JA, Arcaroli JJ, Messersmith WA, Robinson WA, Hirsch FR, Varella-Garcia M, Raben D, Wang XJ, Song JI, Tan AC, Jimeno A.

Mol Oncol. 2013 Aug;7(4):776-90. doi: 10.1016/j.molonc.2013.03.004. Epub 2013 Apr 4.

PMID:
23607916
[PubMed - indexed for MEDLINE]
7.

Signaling via ErbB2 and ErbB3 associates with resistance and epidermal growth factor receptor (EGFR) amplification with sensitivity to EGFR inhibitor gefitinib in head and neck squamous cell carcinoma cells.

Erjala K, Sundvall M, Junttila TT, Zhang N, Savisalo M, Mali P, Kulmala J, Pulkkinen J, Grenman R, Elenius K.

Clin Cancer Res. 2006 Jul 1;12(13):4103-11.

PMID:
16818711
[PubMed - indexed for MEDLINE]
Free Article
8.

Exome sequencing of head and neck squamous cell carcinoma reveals inactivating mutations in NOTCH1.

Agrawal N, Frederick MJ, Pickering CR, Bettegowda C, Chang K, Li RJ, Fakhry C, Xie TX, Zhang J, Wang J, Zhang N, El-Naggar AK, Jasser SA, Weinstein JN, Treviño L, Drummond JA, Muzny DM, Wu Y, Wood LD, Hruban RH, Westra WH, Koch WM, Califano JA, Gibbs RA, Sidransky D, Vogelstein B, Velculescu VE, Papadopoulos N, Wheeler DA, Kinzler KW, Myers JN.

Science. 2011 Aug 26;333(6046):1154-7. doi: 10.1126/science.1206923. Epub 2011 Jul 28.

PMID:
21798897
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Gene status of head and neck squamous cell carcinoma cell lines and cetuximab-mediated biological activities.

Kondo N, Tsukuda M, Taguchi T, Nakazaki K, Sakakibara A, Takahashi H, Toth G, Nishimura G.

Cancer Sci. 2011 Sep;102(9):1717-23. doi: 10.1111/j.1349-7006.2011.01999.x. Epub 2011 Jul 3.

PMID:
21631644
[PubMed - indexed for MEDLINE]
10.

PIK3CA mutations in head and neck squamous cell carcinoma.

Qiu W, Schönleben F, Li X, Ho DJ, Close LG, Manolidis S, Bennett BP, Su GH.

Clin Cancer Res. 2006 Mar 1;12(5):1441-6.

PMID:
16533766
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Copy number amplification of the PIK3CA gene is associated with poor prognosis in non-lymph node metastatic head and neck squamous cell carcinoma.

Suda T, Hama T, Kondo S, Yuza Y, Yoshikawa M, Urashima M, Kato T, Moriyama H.

BMC Cancer. 2012 Sep 20;12:416. doi: 10.1186/1471-2407-12-416.

PMID:
22994622
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Molecular pathways in head and neck cancer: EGFR, PI3K, and more.

Psyrri A, Seiwert TY, Jimeno A.

Am Soc Clin Oncol Educ Book. 2013:246-55. doi: 10.1200/EdBook_AM.2013.33.246.

PMID:
23714515
[PubMed - in process]
Free Article
13.

Expression and mutation analysis of epidermal growth factor receptor in head and neck squamous cell carcinoma.

Sheikh Ali MA, Gunduz M, Nagatsuka H, Gunduz E, Cengiz B, Fukushima K, Beder LB, Demircan K, Fujii M, Yamanaka N, Shimizu K, Grenman R, Nagai N.

Cancer Sci. 2008 Aug;99(8):1589-94. doi: 10.1111/j.1349-7006.2008.00861.x.

PMID:
18754871
[PubMed - indexed for MEDLINE]
14.

Fibroblast growth factor receptors are components of autocrine signaling networks in head and neck squamous cell carcinoma cells.

Marshall ME, Hinz TK, Kono SA, Singleton KR, Bichon B, Ware KE, Marek L, Frederick BA, Raben D, Heasley LE.

Clin Cancer Res. 2011 Aug 1;17(15):5016-25. doi: 10.1158/1078-0432.CCR-11-0050. Epub 2011 Jun 14.

PMID:
21673064
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

The ARF-p16 gene locus in carcinogenesis and therapy of head and neck squamous cell carcinoma.

Yarbrough WG.

Laryngoscope. 2002 Dec;112(12):2114-28.

PMID:
12461329
[PubMed - indexed for MEDLINE]
16.

HER-2/neu oncogene characterization in head and neck squamous cell carcinoma.

Beckhardt RN, Kiyokawa N, Xi L, Liu TJ, Hung MC, el-Naggar AK, Zhang HZ, Clayman GL.

Arch Otolaryngol Head Neck Surg. 1995 Nov;121(11):1265-70.

PMID:
7576473
[PubMed - indexed for MEDLINE]
17.

Effects of pharmacologic antagonists of epidermal growth factor receptor, PI3K and MEK signal kinases on NF-kappaB and AP-1 activation and IL-8 and VEGF expression in human head and neck squamous cell carcinoma lines.

Bancroft CC, Chen Z, Yeh J, Sunwoo JB, Yeh NT, Jackson S, Jackson C, Van Waes C.

Int J Cancer. 2002 Jun 1;99(4):538-48.

PMID:
11992543
[PubMed - indexed for MEDLINE]
18.

Genomic dissection of the epidermal growth factor receptor (EGFR)/PI3K pathway reveals frequent deletion of the EGFR phosphatase PTPRS in head and neck cancers.

Morris LG, Taylor BS, Bivona TG, Gong Y, Eng S, Brennan CW, Kaufman A, Kastenhuber ER, Banuchi VE, Singh B, Heguy A, Viale A, Mellinghoff IK, Huse J, Ganly I, Chan TA.

Proc Natl Acad Sci U S A. 2011 Nov 22;108(47):19024-9. doi: 10.1073/pnas.1111963108. Epub 2011 Nov 7.

PMID:
22065749
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

The dual pathway inhibitor rigosertib is effective in direct patient tumor xenografts of head and neck squamous cell carcinomas.

Anderson RT, Keysar SB, Bowles DW, Glogowska MJ, Astling DP, Morton JJ, Le P, Umpierrez A, Eagles-Soukup J, Gan GN, Vogler BW, Sehrt D, Takimoto SM, Aisner DL, Wilhelm F, Frederick BA, Varella-Garcia M, Tan AC, Jimeno A.

Mol Cancer Ther. 2013 Oct;12(10):1994-2005. doi: 10.1158/1535-7163.MCT-13-0206. Epub 2013 Jul 19.

PMID:
23873848
[PubMed - indexed for MEDLINE]
20.

Clinical significance of genetic alterations and expression of epidermal growth factor receptor (EGFR) in head and neck squamous cell carcinomas.

Szabó B, Nelhubel GA, Kárpáti A, Kenessey I, Jóri B, Székely C, Peták I, Lotz G, Hegedus Z, Hegedus B, Füle T, Döme B, Tímár J, Tóvári J.

Oral Oncol. 2011 Jun;47(6):487-96. doi: 10.1016/j.oraloncology.2011.03.020. Epub 2011 Apr 16.

PMID:
21498106
[PubMed - indexed for MEDLINE]

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