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Items: 1 to 20 of 173

1.

Autophagy of iron-binding proteins may contribute to the oxidative stress resistance of ARPE-19 cells.

Karlsson M, Frennesson C, Gustafsson T, Brunk UT, Nilsson SE, Kurz T.

Exp Eye Res. 2013 Nov;116:359-65.

PMID:
24416768
2.

Autophagy of iron-binding proteins may contribute to the oxidative stress resistance of ARPE-19 cells.

Karlsson M, Frennesson C, Gustafsson T, Brunk UT, Nilsson SE, Kurz T.

Exp Eye Res. 2013 Oct 26. pii: S0014-4835(13)00302-3. doi: 10.1016/j.exer.2013.10.014. [Epub ahead of print]

PMID:
24512774
3.

ARPE-19 retinal pigment epithelial cells are highly resistant to oxidative stress and exercise strict control over their lysosomal redox-active iron.

Kurz T, Karlsson M, Brunk UT, Nilsson SE, Frennesson C.

Autophagy. 2009 May;5(4):494-501. Epub 2009 May 28.

PMID:
19223767
4.

Attenuation of iron-binding proteins in ARPE-19 cells reduces their resistance to oxidative stress.

Karlsson M, Kurz T.

Acta Ophthalmol. 2016 Jun 11. doi: 10.1111/aos.13076. [Epub ahead of print]

PMID:
27287874
5.

Heat shock proteins as gatekeepers of proteolytic pathways-Implications for age-related macular degeneration (AMD).

Kaarniranta K, Salminen A, Eskelinen EL, Kopitz J.

Ageing Res Rev. 2009 Apr;8(2):128-39. Review.

PMID:
19274853
6.

Dysfunction of the retinal pigment epithelium with age: increased iron decreases phagocytosis and lysosomal activity.

Chen H, Lukas TJ, Du N, Suyeoka G, Neufeld AH.

Invest Ophthalmol Vis Sci. 2009 Apr;50(4):1895-902. doi: 10.1167/iovs.08-2850. Epub 2009 Jan 17.

PMID:
19151392
7.

Dysregulated autophagy in the RPE is associated with increased susceptibility to oxidative stress and AMD.

Mitter SK, Song C, Qi X, Mao H, Rao H, Akin D, Lewin A, Grant M, Dunn W Jr, Ding J, Bowes Rickman C, Boulton M.

Autophagy. 2014;10(11):1989-2005. doi: 10.4161/auto.36184.

8.

Autophagy, ageing and apoptosis: the role of oxidative stress and lysosomal iron.

Kurz T, Terman A, Brunk UT.

Arch Biochem Biophys. 2007 Jun 15;462(2):220-30. Epub 2007 Feb 2. Review.

PMID:
17306211
9.

Bmp6 regulates retinal iron homeostasis and has altered expression in age-related macular degeneration.

Hadziahmetovic M, Song Y, Wolkow N, Iacovelli J, Kautz L, Roth MP, Dunaief JL.

Am J Pathol. 2011 Jul;179(1):335-48. doi: 10.1016/j.ajpath.2011.03.033. Epub 2011 May 3.

10.

Induction of autophagy and cell death by tamoxifen in cultured retinal pigment epithelial and photoreceptor cells.

Cho KS, Yoon YH, Choi JA, Lee SJ, Koh JY.

Invest Ophthalmol Vis Sci. 2012 Aug 9;53(9):5344-53. doi: 10.1167/iovs.12-9827.

PMID:
22786900
11.

The oxysterol 27-hydroxycholesterol increases β-amyloid and oxidative stress in retinal pigment epithelial cells.

Dasari B, Prasanthi JR, Marwarha G, Singh BB, Ghribi O.

BMC Ophthalmol. 2010 Sep 13;10:22. doi: 10.1186/1471-2415-10-22.

12.

Metallothionein protects against oxidative stress-induced lysosomal destabilization.

Baird SK, Kurz T, Brunk UT.

Biochem J. 2006 Feb 15;394(Pt 1):275-83.

13.

Effects of lipid peroxidation products on lipofuscinogenesis and autophagy in human retinal pigment epithelial cells.

Krohne TU, Stratmann NK, Kopitz J, Holz FG.

Exp Eye Res. 2010 Mar;90(3):465-71. doi: 10.1016/j.exer.2009.12.011. Epub 2010 Jan 6.

PMID:
20059996
14.

Retinal pigment epithelium (RPE) exosomes contain signaling phosphoproteins affected by oxidative stress.

Biasutto L, Chiechi A, Couch R, Liotta LA, Espina V.

Exp Cell Res. 2013 Aug 1;319(13):2113-23. doi: 10.1016/j.yexcr.2013.05.005. Epub 2013 May 10.

15.

Molecular regulation of cigarette smoke induced-oxidative stress in human retinal pigment epithelial cells: implications for age-related macular degeneration.

Bertram KM, Baglole CJ, Phipps RP, Libby RT.

Am J Physiol Cell Physiol. 2009 Nov;297(5):C1200-10. doi: 10.1152/ajpcell.00126.2009. Epub 2009 Sep 16.

16.

Oxidative stress protection by exogenous delivery of rhHsp70 chaperone to the retinal pigment epithelium (RPE), a possible therapeutic strategy against RPE degeneration.

Subrizi A, Toropainen E, Ramsay E, Airaksinen AJ, Kaarniranta K, Urtti A.

Pharm Res. 2015 Jan;32(1):211-21. doi: 10.1007/s11095-014-1456-6. Epub 2014 Jul 17.

PMID:
25030185
17.

The effect of photo-oxidative stress and inflammatory cytokine on complement factor H expression in retinal pigment epithelial cells.

Lau LI, Chiou SH, Liu CJ, Yen MY, Wei YH.

Invest Ophthalmol Vis Sci. 2011 Aug 29;52(9):6832-41. doi: 10.1167/iovs.11-7815.

PMID:
21743006
18.

The 5HT1a receptor agonist 8-Oh DPAT induces protection from lipofuscin accumulation and oxidative stress in the retinal pigment epithelium.

Thampi P, Rao HV, Mitter SK, Cai J, Mao H, Li H, Seo S, Qi X, Lewin AS, Romano C, Boulton ME.

PLoS One. 2012;7(4):e34468. doi: 10.1371/journal.pone.0034468. Epub 2012 Apr 3.

19.
20.

Autophagy and exosomes in the aged retinal pigment epithelium: possible relevance to drusen formation and age-related macular degeneration.

Wang AL, Lukas TJ, Yuan M, Du N, Tso MO, Neufeld AH.

PLoS One. 2009;4(1):e4160. doi: 10.1371/journal.pone.0004160. Epub 2009 Jan 8.

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