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Items: 1 to 20 of 419

1.

hRAD9 functions as a tumor suppressor by inducing p21-dependent senescence and suppressing epithelial-mesenchymal transition through inhibition of Slug transcription.

Wen FC, Chang TW, Tseng YL, Lee JC, Chang MC.

Carcinogenesis. 2014 Jul;35(7):1481-90. doi: 10.1093/carcin/bgu009. Epub 2014 Jan 8.

2.

GSK3β controls epithelial-mesenchymal transition and tumor metastasis by CHIP-mediated degradation of Slug.

Kao SH, Wang WL, Chen CY, Chang YL, Wu YY, Wang YT, Wang SP, Nesvizhskii AI, Chen YJ, Hong TM, Yang PC.

Oncogene. 2014 Jun 12;33(24):3172-82. doi: 10.1038/onc.2013.279. Epub 2013 Jul 15.

3.

Sohlh2 inhibits ovarian cancer cell proliferation by upregulation of p21 and downregulation of cyclin D1.

Zhang H, Zhang X, Ji S, Hao C, Mu Y, Sun J, Hao J.

Carcinogenesis. 2014 Aug;35(8):1863-71. doi: 10.1093/carcin/bgu113. Epub 2014 May 23.

4.

Pharmacologic reversion of epigenetic silencing of the PRKD1 promoter blocks breast tumor cell invasion and metastasis.

Borges S, Döppler H, Perez EA, Andorfer CA, Sun Z, Anastasiadis PZ, Thompson E, Geiger XJ, Storz P.

Breast Cancer Res. 2013 Aug 23;15(2):R66. doi: 10.1186/bcr3460.

5.

Significances of contactin-1 expression in human gastric cancer and knockdown of contactin-1 expression inhibits invasion and metastasis of MKN45 gastric cancer cells.

Chen DH, Yu JW, Wu JG, Wang SL, Jiang BJ.

J Cancer Res Clin Oncol. 2015 Dec;141(12):2109-20. doi: 10.1007/s00432-015-1973-7. Epub 2015 May 8.

6.

Epigenetic silencing of Aristaless-like homeobox-4, a potential tumor suppressor gene associated with lung cancer.

Liu WB, Han F, Du XH, Jiang X, Li YH, Liu Y, Chen HQ, Ao L, Cui ZH, Cao J, Liu JY.

Int J Cancer. 2014 Mar 15;134(6):1311-22. doi: 10.1002/ijc.28472. Epub 2013 Nov 11.

7.

Benzyl isothiocyanate inhibits epithelial-mesenchymal transition in cultured and xenografted human breast cancer cells.

Sehrawat A, Singh SV.

Cancer Prev Res (Phila). 2011 Jul;4(7):1107-17. doi: 10.1158/1940-6207.CAPR-10-0306. Epub 2011 Apr 4.

8.

IGFBP-rP1 induces p21 expression through a p53-independent pathway, leading to cellular senescence of MCF-7 breast cancer cells.

Zuo S, Liu C, Wang J, Wang F, Xu W, Cui S, Yuan L, Chen X, Fan W, Cui M, Song G.

J Cancer Res Clin Oncol. 2012 Jun;138(6):1045-55. doi: 10.1007/s00432-012-1153-y. Epub 2012 Mar 6.

PMID:
22392074
9.

Notch1 signaling regulates the epithelial-mesenchymal transition and invasion of breast cancer in a Slug-dependent manner.

Shao S, Zhao X, Zhang X, Luo M, Zuo X, Huang S, Wang Y, Gu S, Zhao X.

Mol Cancer. 2015 Feb 3;14:28. doi: 10.1186/s12943-015-0295-3.

10.

ING5 inhibits cancer aggressiveness via preventing EMT and is a potential prognostic biomarker for lung cancer.

Zhang F, Zhang X, Meng J, Zhao Y, Liu X, Liu Y, Wang Y, Li Y, Sun Y, Wang Z, Mei Q, Zhang T.

Oncotarget. 2015 Jun 30;6(18):16239-52.

11.

Wild-type and mutant p53 differentially regulate NADPH oxidase 4 in TGF-β-mediated migration of human lung and breast epithelial cells.

Boudreau HE, Casterline BW, Burke DJ, Leto TL.

Br J Cancer. 2014 May 13;110(10):2569-82. doi: 10.1038/bjc.2014.165. Epub 2014 Apr 8.

12.

Activation of NF-κB by SOD2 promotes the aggressiveness of lung adenocarcinoma by modulating NKX2-1-mediated IKKβ expression.

Chen PM, Wu TC, Wang YC, Cheng YW, Sheu GT, Chen CY, Lee H.

Carcinogenesis. 2013 Nov;34(11):2655-63. doi: 10.1093/carcin/bgt220. Epub 2013 Jun 19.

13.

The metastasis suppressor, N-myc downstream regulated gene 1 (NDRG1), upregulates p21 via p53-independent mechanisms.

Kovacevic Z, Sivagurunathan S, Mangs H, Chikhani S, Zhang D, Richardson DR.

Carcinogenesis. 2011 May;32(5):732-40. doi: 10.1093/carcin/bgr046. Epub 2011 Mar 11.

14.

A novel tumor-promoting role for nuclear factor IA in glioblastomas is mediated through negative regulation of p53, p21, and PAI1.

Lee JS, Xiao J, Patel P, Schade J, Wang J, Deneen B, Erdreich-Epstein A, Song HR.

Neuro Oncol. 2014 Jan;16(2):191-203. doi: 10.1093/neuonc/not167. Epub 2013 Dec 4.

15.
16.

Correlation between Slug transcription factor and miR-221 in MDA-MB-231 breast cancer cells.

Lambertini E, Lolli A, Vezzali F, Penolazzi L, Gambari R, Piva R.

BMC Cancer. 2012 Oct 2;12:445. doi: 10.1186/1471-2407-12-445.

17.

Vimentin regulates EMT induction by Slug and oncogenic H-Ras and migration by governing Axl expression in breast cancer.

Vuoriluoto K, Haugen H, Kiviluoto S, Mpindi JP, Nevo J, Gjerdrum C, Tiron C, Lorens JB, Ivaska J.

Oncogene. 2011 Mar 24;30(12):1436-48. doi: 10.1038/onc.2010.509. Epub 2010 Nov 8.

PMID:
21057535
18.
19.

MiR-124 targets Slug to regulate epithelial-mesenchymal transition and metastasis of breast cancer.

Liang YJ, Wang QY, Zhou CX, Yin QQ, He M, Yu XT, Cao DX, Chen GQ, He JR, Zhao Q.

Carcinogenesis. 2013 Mar;34(3):713-22. doi: 10.1093/carcin/bgs383. Epub 2012 Dec 17.

20.

Direct repression of MYB by ZEB1 suppresses proliferation and epithelial gene expression during epithelial-to-mesenchymal transition of breast cancer cells.

Hugo HJ, Pereira L, Suryadinata R, Drabsch Y, Gonda TJ, Gunasinghe NP, Pinto C, Soo ET, van Denderen BJ, Hill P, Ramsay RG, Sarcevic B, Newgreen DF, Thompson EW.

Breast Cancer Res. 2013 Nov 27;15(6):R113. doi: 10.1186/bcr3580.

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