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Prospecting for unannotated enzymes: discovery of a 3',5'-nucleotide bisphosphate phosphatase within the amidohydrolase superfamily.

Cummings JA, Vetting M, Ghodge SV, Xu C, Hillerich B, Seidel RD, Almo SC, Raushel FM.

Biochemistry. 2014 Jan 28;53(3):591-600. doi: 10.1021/bi401640r. Epub 2014 Jan 13.


YtqI from Bacillus subtilis has both oligoribonuclease and pAp-phosphatase activity.

Mechold U, Fang G, Ngo S, Ogryzko V, Danchin A.

Nucleic Acids Res. 2007;35(13):4552-61. Epub 2007 Jun 22.


Rv2131c from Mycobacterium tuberculosis is a CysQ 3'-phosphoadenosine-5'-phosphatase.

Hatzios SK, Iavarone AT, Bertozzi CR.

Biochemistry. 2008 May 27;47(21):5823-31. doi: 10.1021/bi702453s. Epub 2008 May 3.


Structural elucidation of a dual-activity PAP phosphatase-1 from Entamoeba histolytica capable of hydrolysing both 3'-phosphoadenosine 5'-phosphate and inositol 1,4-bisphosphate.

Faisal Tarique K, Arif Abdul Rehman S, Gourinath S.

Acta Crystallogr D Biol Crystallogr. 2014 Jul;70(Pt 7):2019-31. doi: 10.1107/S1399004714010268. Epub 2014 Jun 29.


Expression, purification and preliminary crystallographic analysis of Mycobacterium tuberculosis CysQ, a phosphatase involved in sulfur metabolism.

Erickson AI, Sarsam RD, Fisher AJ.

Acta Crystallogr F Struct Biol Commun. 2014 Jun;70(Pt 6):750-3. doi: 10.1107/S2053230X14008619. Epub 2014 May 10.


Functional annotation of two new carboxypeptidases from the amidohydrolase superfamily of enzymes.

Xiang DF, Xu C, Kumaran D, Brown AC, Sauder JM, Burley SK, Swaminathan S, Raushel FM.

Biochemistry. 2009 Jun 2;48(21):4567-76. doi: 10.1021/bi900453u.


3'-Phosphoadenosine-5'-phosphate phosphatase activity is required for superoxide stress tolerance in Streptococcus mutans.

Zhang J, Biswas I.

J Bacteriol. 2009 Jul;191(13):4330-40. doi: 10.1128/JB.00184-09. Epub 2009 May 8.


Functional annotation and three-dimensional structure of Dr0930 from Deinococcus radiodurans, a close relative of phosphotriesterase in the amidohydrolase superfamily.

Xiang DF, Kolb P, Fedorov AA, Meier MM, Fedorov LV, Nguyen TT, Sterner R, Almo SC, Shoichet BK, Raushel FM.

Biochemistry. 2009 Mar 17;48(10):2237-47. doi: 10.1021/bi802274f.


Structural and mechanistic characterization of L-histidinol phosphate phosphatase from the polymerase and histidinol phosphatase family of proteins.

Ghodge SV, Fedorov AA, Fedorov EV, Hillerich B, Seidel R, Almo SC, Raushel FM.

Biochemistry. 2013 Feb 12;52(6):1101-12. doi: 10.1021/bi301496p. Epub 2013 Jan 30.


Functional identification of incorrectly annotated prolidases from the amidohydrolase superfamily of enzymes.

Xiang DF, Patskovsky Y, Xu C, Meyer AJ, Sauder JM, Burley SK, Almo SC, Raushel FM.

Biochemistry. 2009 May 5;48(17):3730-42. doi: 10.1021/bi900111q.


Characterization of NrnA homologs from Mycobacterium tuberculosis and Mycoplasma pneumoniae.

Postic G, Danchin A, Mechold U.

RNA. 2012 Jan;18(1):155-65. doi: 10.1261/rna.029132.111. Epub 2011 Nov 23.


Structure-based identification of inositol polyphosphate 1-phosphatase from Entamoeba histolytica.

Faisal Tarique K, Arif Abdul Rehman S, Betzel C, Gourinath S.

Acta Crystallogr D Biol Crystallogr. 2014 Nov;70(Pt 11):3023-33. doi: 10.1107/S1399004714021245. Epub 2014 Oct 29.


Divergence of biochemical function in the HAD superfamily: D-glycero-D-manno-heptose-1,7-bisphosphate phosphatase (GmhB).

Wang L, Huang H, Nguyen HH, Allen KN, Mariano PS, Dunaway-Mariano D.

Biochemistry. 2010 Feb 16;49(6):1072-81. doi: 10.1021/bi902018y.


A novel target of lithium therapy.

Yenush L, Bellés JM, López-Coronado JM, Gil-Mascarell R, Serrano R, Rodríguez PL.

FEBS Lett. 2000 Feb 11;467(2-3):321-5.


Structure and function of an archaeal homolog of survival protein E (SurEalpha): an acid phosphatase with purine nucleotide specificity.

Mura C, Katz JE, Clarke SG, Eisenberg D.

J Mol Biol. 2003 Mar 7;326(5):1559-75. Erratum in: J Mol Biol. 2003 Apr 25;328(2):517.


Structural basis for the divergence of substrate specificity and biological function within HAD phosphatases in lipopolysaccharide and sialic acid biosynthesis.

Daughtry KD, Huang H, Malashkevich V, Patskovsky Y, Liu W, Ramagopal U, Sauder JM, Burley SK, Almo SC, Dunaway-Mariano D, Allen KN.

Biochemistry. 2013 Aug 13;52(32):5372-86. doi: 10.1021/bi400659k. Epub 2013 Jul 29.


Crystal structure of Saccharomyces cerevisiae 3'-phosphoadenosine-5'-phosphosulfate reductase complexed with adenosine 3',5'-bisphosphate.

Yu Z, Lemongello D, Segel IH, Fisher AJ.

Biochemistry. 2008 Dec 2;47(48):12777-86. doi: 10.1021/bi801118f.

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