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Items: 1 to 20 of 101

1.

Lipopolysaccharide-induced lung injury involves the nitration-mediated activation of RhoA.

Rafikov R, Dimitropoulou C, Aggarwal S, Kangath A, Gross C, Pardo D, Sharma S, Jezierska-Drutel A, Patel V, Snead C, Lucas R, Verin A, Fulton D, Catravas JD, Black SM.

J Biol Chem. 2014 Feb 21;289(8):4710-22. doi: 10.1074/jbc.M114.547596. Epub 2014 Jan 7.

2.

Conditional deletion of FAK in mice endothelium disrupts lung vascular barrier function due to destabilization of RhoA and Rac1 activities.

Schmidt TT, Tauseef M, Yue L, Bonini MG, Gothert J, Shen TL, Guan JL, Predescu S, Sadikot R, Mehta D.

Am J Physiol Lung Cell Mol Physiol. 2013 Aug 15;305(4):L291-300. doi: 10.1152/ajplung.00094.2013. Epub 2013 Jun 14.

3.

Dimethylarginine dimethylaminohydrolase II overexpression attenuates LPS-mediated lung leak in acute lung injury.

Aggarwal S, Gross CM, Kumar S, Dimitropoulou C, Sharma S, Gorshkov BA, Sridhar S, Lu Q, Bogatcheva NV, Jezierska-Drutel AJ, Lucas R, Verin AD, Catravas JD, Black SM.

Am J Respir Cell Mol Biol. 2014 Mar;50(3):614-25. doi: 10.1165/rcmb.2013-0193OC.

4.

Inhibition of AMP-activated protein kinase accentuates lipopolysaccharide-induced lung endothelial barrier dysfunction and lung injury in vivo.

Xing J, Wang Q, Coughlan K, Viollet B, Moriasi C, Zou MH.

Am J Pathol. 2013 Mar;182(3):1021-30. doi: 10.1016/j.ajpath.2012.11.022. Epub 2013 Jan 7.

5.

Heat shock protein 90 inhibitors prevent LPS-induced endothelial barrier dysfunction by disrupting RhoA signaling.

Joshi AD, Dimitropoulou C, Thangjam G, Snead C, Feldman S, Barabutis N, Fulton D, Hou Y, Kumar S, Patel V, Gorshkov B, Verin AD, Black SM, Catravas JD.

Am J Respir Cell Mol Biol. 2014 Jan;50(1):170-9. doi: 10.1165/rcmb.2012-0496OC.

6.

Hyaluronic Acid binding protein 2 is a novel regulator of vascular integrity.

Mambetsariev N, Mirzapoiazova T, Mambetsariev B, Sammani S, Lennon FE, Garcia JG, Singleton PA.

Arterioscler Thromb Vasc Biol. 2010 Mar;30(3):483-90. doi: 10.1161/ATVBAHA.109.200451. Epub 2009 Dec 30.

7.

Endothelial nitric oxide synthase deficient mice are protected from lipopolysaccharide induced acute lung injury.

Gross CM, Rafikov R, Kumar S, Aggarwal S, Ham PB 3rd, Meadows ML, Cherian-Shaw M, Kangath A, Sridhar S, Lucas R, Black SM.

PLoS One. 2015 Mar 18;10(3):e0119918. doi: 10.1371/journal.pone.0119918. eCollection 2015.

8.

Caveolin-1-eNOS signaling promotes p190RhoGAP-A nitration and endothelial permeability.

Siddiqui MR, Komarova YA, Vogel SM, Gao X, Bonini MG, Rajasingh J, Zhao YY, Brovkovych V, Malik AB.

J Cell Biol. 2011 May 30;193(5):841-50. doi: 10.1083/jcb.201012129.

9.

Opposite effects of ANP receptors in attenuation of LPS-induced endothelial permeability and lung injury.

Xing J, Yakubov B, Poroyko V, Birukova AA.

Microvasc Res. 2012 Mar;83(2):194-9. doi: 10.1016/j.mvr.2011.09.012. Epub 2011 Oct 6.

10.

Asef mediates HGF protective effects against LPS-induced lung injury and endothelial barrier dysfunction.

Meng F, Meliton A, Moldobaeva N, Mutlu G, Kawasaki Y, Akiyama T, Birukova AA.

Am J Physiol Lung Cell Mol Physiol. 2015 Mar 1;308(5):L452-63. doi: 10.1152/ajplung.00170.2014. Epub 2014 Dec 24.

11.

Mechanisms of nitric oxide synthase uncoupling in endotoxin-induced acute lung injury: role of asymmetric dimethylarginine.

Sharma S, Smith A, Kumar S, Aggarwal S, Rehmani I, Snead C, Harmon C, Fineman J, Fulton D, Catravas JD, Black SM.

Vascul Pharmacol. 2010 May-Jun;52(5-6):182-90. doi: 10.1016/j.vph.2009.11.010. Epub 2009 Dec 3.

12.

Cigarette smoke causes lung vascular barrier dysfunction via oxidative stress-mediated inhibition of RhoA and focal adhesion kinase.

Lu Q, Sakhatskyy P, Grinnell K, Newton J, Ortiz M, Wang Y, Sanchez-Esteban J, Harrington EO, Rounds S.

Am J Physiol Lung Cell Mol Physiol. 2011 Dec;301(6):L847-57. doi: 10.1152/ajplung.00178.2011. Epub 2011 Oct 7.

13.

Genetic disruption of protein kinase Cδ reduces endotoxin-induced lung injury.

Chichger H, Grinnell KL, Casserly B, Chung CS, Braza J, Lomas-Neira J, Ayala A, Rounds S, Klinger JR, Harrington EO.

Am J Physiol Lung Cell Mol Physiol. 2012 Nov 15;303(10):L880-8. doi: 10.1152/ajplung.00169.2012. Epub 2012 Sep 14.

14.

Conditioned media from adipose stromal cells limit lipopolysaccharide-induced lung injury, endothelial hyperpermeability and apoptosis.

Lu H, Poirier C, Cook T, Traktuev DO, Merfeld-Clauss S, Lease B, Petrache I, March KL, Bogatcheva NV.

J Transl Med. 2015 Feb 21;13:67. doi: 10.1186/s12967-015-0422-3.

15.

Expression of IL-17A and IL-17F in lipopolysaccharide-induced acute lung injury and the counteraction of anisodamine or methylprednisolone.

You QH, Zhang D, Niu CC, Zhu ZM, Wang N, Yue Y, Sun GY.

Cytokine. 2014 Mar;66(1):78-86. doi: 10.1016/j.cyto.2013.12.019. Epub 2014 Jan 25.

PMID:
24548428
16.

Histone deacetylase inhibitors prevent pulmonary endothelial hyperpermeability and acute lung injury by regulating heat shock protein 90 function.

Joshi AD, Barabutis N, Birmpas C, Dimitropoulou C, Thangjam G, Cherian-Shaw M, Dennison J, Catravas JD.

Am J Physiol Lung Cell Mol Physiol. 2015 Dec 15;309(12):L1410-9. doi: 10.1152/ajplung.00180.2015. Epub 2015 Oct 23.

PMID:
26498249
17.

Role of sphingomyelin synthesis in pulmonary endothelial cell cytoskeletal activation and endotoxin-induced lung injury.

Anjum F, Joshi K, Grinkina N, Gowda S, Cutaia M, Wadgaonkar R.

Am J Respir Cell Mol Biol. 2012 Jul;47(1):94-103. doi: 10.1165/rcmb.2010-0458OC. Epub 2012 Feb 23.

PMID:
22362386
18.

RhoGDI-1 modulation of the activity of monomeric RhoGTPase RhoA regulates endothelial barrier function in mouse lungs.

Gorovoy M, Neamu R, Niu J, Vogel S, Predescu D, Miyoshi J, Takai Y, Kini V, Mehta D, Malik AB, Voyno-Yasenetskaya T.

Circ Res. 2007 Jul 6;101(1):50-8. Epub 2007 May 24.

19.

p53 protects against LPS-induced lung endothelial barrier dysfunction.

Barabutis N, Dimitropoulou C, Birmpas C, Joshi A, Thangjam G, Catravas JD.

Am J Physiol Lung Cell Mol Physiol. 2015 Apr 15;308(8):L776-87. doi: 10.1152/ajplung.00334.2014. Epub 2015 Feb 20.

20.

A modified "double-hit" induced acute lung injury model in rats and protective effects of tetramethylpyrazine on the injury via Rho/ROCK pathway.

Zhao S, Zhang Y, Chen Q, Dong S, Zhang G, Li J, Yang X, Li Y.

Int J Clin Exp Pathol. 2015 May 1;8(5):4581-7. eCollection 2015.

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