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Results: 1 to 20 of 104

1.

Pitx2, an atrial fibrillation predisposition gene, directly regulates ion transport and intercalated disc genes.

Tao Y, Zhang M, Li L, Bai Y, Zhou Y, Moon AM, Kaminski HJ, Martin JF.

Circ Cardiovasc Genet. 2014 Feb;7(1):23-32. doi: 10.1161/CIRCGENETICS.113.000259. Epub 2014 Jan 6.

PMID:
24395921
[PubMed - indexed for MEDLINE]
2.

Pitx2-microRNA pathway that delimits sinoatrial node development and inhibits predisposition to atrial fibrillation.

Wang J, Bai Y, Li N, Ye W, Zhang M, Greene SB, Tao Y, Chen Y, Wehrens XH, Martin JF.

Proc Natl Acad Sci U S A. 2014 Jun 24;111(25):9181-6. doi: 10.1073/pnas.1405411111. Epub 2014 Jun 10.

PMID:
24927531
[PubMed - indexed for MEDLINE]
Free Article
3.

Pitx2 prevents susceptibility to atrial arrhythmias by inhibiting left-sided pacemaker specification.

Wang J, Klysik E, Sood S, Johnson RL, Wehrens XH, Martin JF.

Proc Natl Acad Sci U S A. 2010 May 25;107(21):9753-8. doi: 10.1073/pnas.0912585107. Epub 2010 May 10.

PMID:
20457925
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

PITX2 insufficiency leads to atrial electrical and structural remodeling linked to arrhythmogenesis.

Chinchilla A, Daimi H, Lozano-Velasco E, Dominguez JN, Caballero R, Delpón E, Tamargo J, Cinca J, Hove-Madsen L, Aranega AE, Franco D.

Circ Cardiovasc Genet. 2011 Jun;4(3):269-79. doi: 10.1161/CIRCGENETICS.110.958116. Epub 2011 Apr 21.

PMID:
21511879
[PubMed - indexed for MEDLINE]
Free Article
5.

PITX2c is expressed in the adult left atrium, and reducing Pitx2c expression promotes atrial fibrillation inducibility and complex changes in gene expression.

Kirchhof P, Kahr PC, Kaese S, Piccini I, Vokshi I, Scheld HH, Rotering H, Fortmueller L, Laakmann S, Verheule S, Schotten U, Fabritz L, Brown NA.

Circ Cardiovasc Genet. 2011 Apr;4(2):123-33. doi: 10.1161/CIRCGENETICS.110.958058. Epub 2011 Jan 31.

PMID:
21282332
[PubMed - indexed for MEDLINE]
Free Article
6.

Atrial Fibrillation associated chromosome 4q25 variants are not associated with PITX2c expression in human adult left atrial appendages.

Gore-Panter SR, Hsu J, Hanna P, Gillinov AM, Pettersson G, Newton DW, Moravec CS, Van Wagoner DR, Chung MK, Barnard J, Smith JD.

PLoS One. 2014 Jan 22;9(1):e86245. doi: 10.1371/journal.pone.0086245. eCollection 2014.

PMID:
24465984
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Gene expression profiling of human atrial myocardium with atrial fibrillation by DNA microarray analysis.

Ohki R, Yamamoto K, Ueno S, Mano H, Misawa Y, Fuse K, Ikeda U, Shimada K.

Int J Cardiol. 2005 Jul 10;102(2):233-8.

PMID:
15982490
[PubMed - indexed for MEDLINE]
8.

Myocardial Pitx2 differentially regulates the left atrial identity and ventricular asymmetric remodeling programs.

Tessari A, Pietrobon M, Notte A, Cifelli G, Gage PJ, Schneider MD, Lembo G, Campione M.

Circ Res. 2008 Apr 11;102(7):813-22. doi: 10.1161/CIRCRESAHA.107.163188. Epub 2008 Feb 21.

PMID:
18292603
[PubMed - indexed for MEDLINE]
Free Article
9.

Modulation of conductive elements by Pitx2 and their impact on atrial arrhythmogenesis.

Franco D, Chinchilla A, Daimi H, Dominguez JN, Aránega A.

Cardiovasc Res. 2011 Jul 15;91(2):223-31. doi: 10.1093/cvr/cvr078. Epub 2011 Mar 22. Review.

PMID:
21427120
[PubMed - indexed for MEDLINE]
Free Article
10.

Chromosome 4q25 variants are genetic modifiers of rare ion channel mutations associated with familial atrial fibrillation.

Ritchie MD, Rowan S, Kucera G, Stubblefield T, Blair M, Carter S, Roden DM, Darbar D.

J Am Coll Cardiol. 2012 Sep 25;60(13):1173-81. doi: 10.1016/j.jacc.2012.04.030. Epub 2012 Jul 18.

PMID:
22818067
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Is Pitx2 growing up?

Clauss S, Kääb S.

Circ Cardiovasc Genet. 2011 Apr;4(2):105-7. doi: 10.1161/CIRCGENETICS.111.959791. No abstract available.

PMID:
21505199
[PubMed - indexed for MEDLINE]
Free Article
12.

Mutational analysis of the PITX2 and NKX2-5 genes in patients with idiopathic atrial fibrillation.

Boldt LH, Posch MG, Perrot A, Polotzki M, Rolf S, Parwani AS, Huemer M, Wutzler A, Ozcelik C, Haverkamp W.

Int J Cardiol. 2010 Nov 19;145(2):316-7. doi: 10.1016/j.ijcard.2009.11.023.

PMID:
20022124
[PubMed - indexed for MEDLINE]
13.

Homeobox transcription factor Pitx2: The rise of an asymmetry gene in cardiogenesis and arrhythmogenesis.

Franco D, Christoffels VM, Campione M.

Trends Cardiovasc Med. 2014 Jan;24(1):23-31. doi: 10.1016/j.tcm.2013.06.001. Epub 2013 Aug 15. Review.

PMID:
23953978
[PubMed - indexed for MEDLINE]
14.

MicroRNA-328 contributes to adverse electrical remodeling in atrial fibrillation.

Lu Y, Zhang Y, Wang N, Pan Z, Gao X, Zhang F, Zhang Y, Shan H, Luo X, Bai Y, Sun L, Song W, Xu C, Wang Z, Yang B.

Circulation. 2010 Dec 7;122(23):2378-87. doi: 10.1161/CIRCULATIONAHA.110.958967. Epub 2010 Nov 22. Erratum in: Circulation. 2011 Sep 20;124(12):e334.

PMID:
21098446
[PubMed - indexed for MEDLINE]
Free Article
15.

Region-specific gene expression profiles in the left atria of patients with valvular atrial fibrillation.

Yeh YH, Kuo CT, Lee YS, Lin YM, Nattel S, Tsai FC, Chen WJ.

Heart Rhythm. 2013 Mar;10(3):383-91. doi: 10.1016/j.hrthm.2012.11.013. Epub 2012 Nov 24.

PMID:
23183193
[PubMed - indexed for MEDLINE]
16.

Human atrial ion channel and transporter subunit gene-expression remodeling associated with valvular heart disease and atrial fibrillation.

Gaborit N, Steenman M, Lamirault G, Le Meur N, Le Bouter S, Lande G, Léger J, Charpentier F, Christ T, Dobrev D, Escande D, Nattel S, Demolombe S.

Circulation. 2005 Jul 26;112(4):471-81. Epub 2005 Jul 18.

PMID:
16027256
[PubMed - indexed for MEDLINE]
Free Article
17.

Novel genetic markers associate with atrial fibrillation risk in Europeans and Japanese.

Lubitz SA, Lunetta KL, Lin H, Arking DE, Trompet S, Li G, Krijthe BP, Chasman DI, Barnard J, Kleber ME, Dörr M, Ozaki K, Smith AV, Müller-Nurasyid M, Walter S, Agarwal SK, Bis JC, Brody JA, Chen LY, Everett BM, Ford I, Franco OH, Harris TB, Hofman A, Kääb S, Mahida S, Kathiresan S, Kubo M, Launer LJ, Macfarlane PW, Magnani JW, McKnight B, McManus DD, Peters A, Psaty BM, Rose LM, Rotter JI, Silbernagel G, Smith JD, Sotoodehnia N, Stott DJ, Taylor KD, Tomaschitz A, Tsunoda T, Uitterlinden AG, Van Wagoner DR, Völker U, Völzke H, Murabito JM, Sinner MF, Gudnason V, Felix SB, März W, Chung M, Albert CM, Stricker BH, Tanaka T, Heckbert SR, Jukema JW, Alonso A, Benjamin EJ, Ellinor PT.

J Am Coll Cardiol. 2014 Apr 1;63(12):1200-10. doi: 10.1016/j.jacc.2013.12.015. Epub 2014 Jan 30.

PMID:
24486271
[PubMed - indexed for MEDLINE]
18.

Gene expression and genetic variation in human atria.

Lin H, Dolmatova EV, Morley MP, Lunetta KL, McManus DD, Magnani JW, Margulies KB, Hakonarson H, del Monte F, Benjamin EJ, Cappola TP, Ellinor PT.

Heart Rhythm. 2014 Feb;11(2):266-71. doi: 10.1016/j.hrthm.2013.10.051. Epub 2013 Oct 28.

PMID:
24177373
[PubMed - indexed for MEDLINE]
19.

Targeted sequencing in candidate genes for atrial fibrillation: the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Targeted Sequencing Study.

Lin H, Sinner MF, Brody JA, Arking DE, Lunetta KL, Rienstra M, Lubitz SA, Magnani JW, Sotoodehnia N, McKnight B, McManus DD, Boerwinkle E, Psaty BM, Rotter JI, Bis JC, Gibbs RA, Muzny D, Kovar CL, Morrison AC, Gupta M, Folsom AR, Kääb S, Heckbert SR, Alonso A, Ellinor PT, Benjamin EJ; CHARGE Atrial Fibrillation Working Group.

Heart Rhythm. 2014 Mar;11(3):452-7. doi: 10.1016/j.hrthm.2013.11.012. Epub 2013 Nov 14.

PMID:
24239840
[PubMed - indexed for MEDLINE]
20.

Genomic profiling reveals Pitx2 controls expression of mature extraocular muscle contraction-related genes.

Zhou Y, Gong B, Kaminski HJ.

Invest Ophthalmol Vis Sci. 2012 Apr 18;53(4):1821-9. doi: 10.1167/iovs.12-9481.

PMID:
22408009
[PubMed - indexed for MEDLINE]
Free PMC Article

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