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Items: 1 to 20 of 100

1.

Nobiletin suppresses MMP-9 expression through modulation of p38 MAPK activity in human dermal fibrobalsts.

Kim JJ, Korm S, Kim WS, Kim OS, Lee JS, Min HG, Chin YW, Cha HJ.

Biol Pharm Bull. 2014;37(1):158-63.

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3.

Michelia alba extract attenuates UVB-induced expression of matrix metalloproteinases via MAP kinase pathway in human dermal fibroblasts.

Chiang HM, Chen HC, Lin TJ, Shih IC, Wen KC.

Food Chem Toxicol. 2012 Dec;50(12):4260-9. doi: 10.1016/j.fct.2012.08.018. Epub 2012 Aug 17.

PMID:
22922035
4.

IL-17 stimulates MMP-1 expression in primary human cardiac fibroblasts via p38 MAPK- and ERK1/2-dependent C/EBP-beta , NF-kappaB, and AP-1 activation.

Cortez DM, Feldman MD, Mummidi S, Valente AJ, Steffensen B, Vincenti M, Barnes JL, Chandrasekar B.

Am J Physiol Heart Circ Physiol. 2007 Dec;293(6):H3356-65. Epub 2007 Oct 5.

5.

Antimetastatic effect of nobiletin through the down-regulation of CXC chemokine receptor type 4 and matrix metallopeptidase-9.

Baek SH, Kim SM, Nam D, Lee JH, Ahn KS, Choi SH, Kim SH, Shim BS, Chang IM, Ahn KS.

Pharm Biol. 2012 Oct;50(10):1210-8. doi: 10.3109/13880209.2012.664151. Epub 2012 Aug 2.

PMID:
22853317
6.

Nobiletin, a citrus flavonoid, suppresses invasion and migration involving FAK/PI3K/Akt and small GTPase signals in human gastric adenocarcinoma AGS cells.

Lee YC, Cheng TH, Lee JS, Chen JH, Liao YC, Fong Y, Wu CH, Shih YW.

Mol Cell Biochem. 2011 Jan;347(1-2):103-15. doi: 10.1007/s11010-010-0618-z. Epub 2010 Oct 21.

PMID:
20963626
7.
8.

(-)Epigallocatechin gallate hampers collagen destruction and collagenase activation in ultraviolet-B-irradiated human dermal fibroblasts: involvement of mitogen-activated protein kinase.

Bae JY, Choi JS, Choi YJ, Shin SY, Kang SW, Han SJ, Kang YH.

Food Chem Toxicol. 2008 Apr;46(4):1298-307. doi: 10.1016/j.fct.2007.09.112. Epub 2007 Dec 8.

PMID:
18226437
9.

Inhibitory effect of Zingiber cassumunar extracts on lipopolysaccharide-induced cyclooxygenase-2 and matrix metalloproteinase expression in human gingival fibroblasts.

Koontongkaew S, Meesuk L, Aupaphong V, Ayudhaya TD, Poachanukoon O.

J Periodontal Res. 2013 Aug;48(4):507-16. doi: 10.1111/jre.12033. Epub 2012 Dec 30.

PMID:
23278498
10.

Citrus nobiletin suppresses inducible nitric oxide synthase gene expression in interleukin-1β-treated hepatocytes.

Yoshigai E, Machida T, Okuyama T, Mori M, Murase H, Yamanishi R, Okumura T, Ikeya Y, Nishino H, Nishizawa M.

Biochem Biophys Res Commun. 2013 Sep 13;439(1):54-9. doi: 10.1016/j.bbrc.2013.08.029. Epub 2013 Aug 16.

PMID:
23958298
11.

Novel anti-inflammatory actions of nobiletin, a citrus polymethoxy flavonoid, on human synovial fibroblasts and mouse macrophages.

Lin N, Sato T, Takayama Y, Mimaki Y, Sashida Y, Yano M, Ito A.

Biochem Pharmacol. 2003 Jun 15;65(12):2065-71.

PMID:
12787887
13.

Cultivated ginseng suppresses ultraviolet B-induced collagenase activation via mitogen-activated protein kinases and nuclear factor κB/activator protein-1-dependent signaling in human dermal fibroblasts.

Hwang YP, Choi JH, Kim HG, Choi JM, Hwang SK, Chung YC, Jeong HG.

Nutr Res. 2012 Jun;32(6):428-38. doi: 10.1016/j.nutres.2012.04.005. Epub 2012 May 29.

PMID:
22749179
14.
15.

Activation of p38 and JNK MAPK pathways abrogates requirement for new protein synthesis for phorbol ester mediated induction of select MMP and TIMP genes.

Sampieri CL, Nuttall RK, Young DA, Goldspink D, Clark IM, Edwards DR.

Matrix Biol. 2008 Mar;27(2):128-38. Epub 2007 Oct 4.

PMID:
18029162
16.

A citrus polymethoxyflavonoid, nobiletin, is a novel MEK inhibitor that exhibits antitumor metastasis in human fibrosarcoma HT-1080 cells.

Miyata Y, Sato T, Imada K, Dobashi A, Yano M, Ito A.

Biochem Biophys Res Commun. 2008 Feb 1;366(1):168-73. Epub 2007 Nov 29.

PMID:
18053806
17.

Nobiletin, a dietary phytochemical, inhibits vascular smooth muscle cells proliferation via calcium-mediated c-Jun N-terminal kinases pathway.

Zhou CH, Wu XH, Wu YQ.

Eur J Pharmacol. 2009 Aug 1;615(1-3):55-60. doi: 10.1016/j.ejphar.2009.05.025. Epub 2009 May 30.

PMID:
19486902
18.

Transforming growth factor-beta induces collagenase-3 expression by human gingival fibroblasts via p38 mitogen-activated protein kinase.

Ravanti L, Häkkinen L, Larjava H, Saarialho-Kere U, Foschi M, Han J, Kähäri VM.

J Biol Chem. 1999 Dec 24;274(52):37292-300.

20.

Polymethoxylated flavones potentiate the cytolytic activity of NK leukemia cell line KHYG-1 via enhanced expression of granzyme B.

Saito T, Abe D, Nogata Y.

Biochem Biophys Res Commun. 2015 Jan 16;456(3):799-803. doi: 10.1016/j.bbrc.2014.12.027. Epub 2014 Dec 13.

PMID:
25511703
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