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Similar articles for PubMed (Select 24389360)

1.

Identification of novel alternative splicing events in the huntingtin gene and assessment of the functional consequences using structural protein homology modelling.

Hughes AC, Mort M, Elliston L, Thomas RM, Brooks SP, Dunnett SB, Jones L.

J Mol Biol. 2014 Apr 3;426(7):1428-38. doi: 10.1016/j.jmb.2013.12.028. Epub 2014 Jan 3.

PMID:
24389360
2.

Aberrantly spliced HTT, a new player in Huntington's disease pathogenesis.

Gipson TA, Neueder A, Wexler NS, Bates GP, Housman D.

RNA Biol. 2013 Nov;10(11):1647-52. doi: 10.4161/rna.26706. Epub 2013 Oct 11.

3.

The Hdh(Q150/Q150) knock-in mouse model of HD and the R6/2 exon 1 model develop comparable and widespread molecular phenotypes.

Woodman B, Butler R, Landles C, Lupton MK, Tse J, Hockly E, Moffitt H, Sathasivam K, Bates GP.

Brain Res Bull. 2007 Apr 30;72(2-3):83-97. Epub 2006 Dec 5.

PMID:
17352931
5.

Aberrant splicing of HTT generates the pathogenic exon 1 protein in Huntington disease.

Sathasivam K, Neueder A, Gipson TA, Landles C, Benjamin AC, Bondulich MK, Smith DL, Faull RL, Roos RA, Howland D, Detloff PJ, Housman DE, Bates GP.

Proc Natl Acad Sci U S A. 2013 Feb 5;110(6):2366-70. doi: 10.1073/pnas.1221891110. Epub 2013 Jan 22.

6.

Replacement of huntingtin exon 1 by trans-splicing.

Rindt H, Yen PF, Thebeau CN, Peterson TS, Weisman GA, Lorson CL.

Cell Mol Life Sci. 2012 Dec;69(24):4191-204. doi: 10.1007/s00018-012-1083-5. Epub 2012 Jul 20.

7.

A natural antisense transcript at the Huntington's disease repeat locus regulates HTT expression.

Chung DW, Rudnicki DD, Yu L, Margolis RL.

Hum Mol Genet. 2011 Sep 1;20(17):3467-77. doi: 10.1093/hmg/ddr263. Epub 2011 Jun 13.

8.

Potent and selective antisense oligonucleotides targeting single-nucleotide polymorphisms in the Huntington disease gene / allele-specific silencing of mutant huntingtin.

Carroll JB, Warby SC, Southwell AL, Doty CN, Greenlee S, Skotte N, Hung G, Bennett CF, Freier SM, Hayden MR.

Mol Ther. 2011 Dec;19(12):2178-85. doi: 10.1038/mt.2011.201. Epub 2011 Oct 4.

9.

Formation of polyglutamine inclusions in a wide range of non-CNS tissues in the HdhQ150 knock-in mouse model of Huntington's disease.

Moffitt H, McPhail GD, Woodman B, Hobbs C, Bates GP.

PLoS One. 2009 Nov 30;4(11):e8025. doi: 10.1371/journal.pone.0008025.

10.

Proteomic analysis of wild-type and mutant huntingtin-associated proteins in mouse brains identifies unique interactions and involvement in protein synthesis.

Culver BP, Savas JN, Park SK, Choi JH, Zheng S, Zeitlin SO, Yates JR 3rd, Tanese N.

J Biol Chem. 2012 Jun 22;287(26):21599-614. doi: 10.1074/jbc.M112.359307. Epub 2012 May 3.

11.

Differential effects of the Huntington's disease CAG mutation in striatum and cerebellum are quantitative not qualitative.

Fossale E, Seong IS, Coser KR, Shioda T, Kohane IS, Wheeler VC, Gusella JF, MacDonald ME, Lee JM.

Hum Mol Genet. 2011 Nov 1;20(21):4258-67. doi: 10.1093/hmg/ddr355. Epub 2011 Aug 12.

12.

Mutant huntingtin's effects on striatal gene expression in mice recapitulate changes observed in human Huntington's disease brain and do not differ with mutant huntingtin length or wild-type huntingtin dosage.

Kuhn A, Goldstein DR, Hodges A, Strand AD, Sengstag T, Kooperberg C, Becanovic K, Pouladi MA, Sathasivam K, Cha JH, Hannan AJ, Hayden MR, Leavitt BR, Dunnett SB, Ferrante RJ, Albin R, Shelbourne P, Delorenzi M, Augood SJ, Faull RL, Olson JM, Bates GP, Jones L, Luthi-Carter R.

Hum Mol Genet. 2007 Aug 1;16(15):1845-61. Epub 2007 May 21.

13.

Lack of huntingtin promotes neural stem cells differentiation into glial cells while neurons expressing huntingtin with expanded polyglutamine tracts undergo cell death.

Conforti P, Camnasio S, Mutti C, Valenza M, Thompson M, Fossale E, Zeitlin S, MacDonald ME, Zuccato C, Cattaneo E.

Neurobiol Dis. 2013 Feb;50:160-70. doi: 10.1016/j.nbd.2012.10.015. Epub 2012 Oct 23.

PMID:
23089356
14.
15.

Comparison of huntingtin proteolytic fragments in human lymphoblast cell lines and human brain.

Toneff T, Mende-Mueller L, Wu Y, Hwang SR, Bundey R, Thompson LM, Chesselet MF, Hook V.

J Neurochem. 2002 Jul;82(1):84-92.

PMID:
12091468
16.

Elucidating a normal function of huntingtin by functional and microarray analysis of huntingtin-null mouse embryonic fibroblasts.

Zhang H, Das S, Li QZ, Dragatsis I, Repa J, Zeitlin S, Hajnóczky G, Bezprozvanny I.

BMC Neurosci. 2008 Apr 15;9:38. doi: 10.1186/1471-2202-9-38.

17.

Evidence that "brain-specific" FOX-1, FOX-2, and nPTB alternatively spliced isoforms are produced in the lens.

Bitel CL, Nathan R, Wong P, Kuppasani S, Matsushita M, Kanazawa H, Frederikse PH.

Curr Eye Res. 2011 Apr;36(4):321-7.

PMID:
21714144
18.
19.

Phosphorodiamidate morpholino oligomers suppress mutant huntingtin expression and attenuate neurotoxicity.

Sun X, Marque LO, Cordner Z, Pruitt JL, Bhat M, Li PP, Kannan G, Ladenheim EE, Moran TH, Margolis RL, Rudnicki DD.

Hum Mol Genet. 2014 Dec 1;23(23):6302-17. doi: 10.1093/hmg/ddu349. Epub 2014 Jul 4.

PMID:
25035419
20.

A pathogenic mechanism in Huntington's disease involves small CAG-repeated RNAs with neurotoxic activity.

Bañez-Coronel M, Porta S, Kagerbauer B, Mateu-Huertas E, Pantano L, Ferrer I, Guzmán M, Estivill X, Martí E.

PLoS Genet. 2012;8(2):e1002481. doi: 10.1371/journal.pgen.1002481. Epub 2012 Feb 23.

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