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Results: 1 to 20 of 98

1.

The PAF complex and Prf1/Rtf1 delineate distinct Cdk9-dependent pathways regulating transcription elongation in fission yeast.

Mbogning J, Nagy S, Pagé V, Schwer B, Shuman S, Fisher RP, Tanny JC.

PLoS Genet. 2013;9(12):e1004029. doi: 10.1371/journal.pgen.1004029. Epub 2013 Dec 26.

PMID:
24385927
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

A positive feedback loop links opposing functions of P-TEFb/Cdk9 and histone H2B ubiquitylation to regulate transcript elongation in fission yeast.

Sansó M, Lee KM, Viladevall L, Jacques PÉ, Pagé V, Nagy S, Racine A, St Amour CV, Zhang C, Shokat KM, Schwer B, Robert F, Fisher RP, Tanny JC.

PLoS Genet. 2012;8(8):e1002822. doi: 10.1371/journal.pgen.1002822. Epub 2012 Aug 2.

PMID:
22876190
[PubMed - indexed for MEDLINE]
Free PMC Article
3.
4.

Separate domains of fission yeast Cdk9 (P-TEFb) are required for capping enzyme recruitment and primed (Ser7-phosphorylated) Rpb1 carboxyl-terminal domain substrate recognition.

St Amour CV, Sansó M, Bösken CA, Lee KM, Larochelle S, Zhang C, Shokat KM, Geyer M, Fisher RP.

Mol Cell Biol. 2012 Jul;32(13):2372-83. doi: 10.1128/MCB.06657-11. Epub 2012 Apr 16.

PMID:
22508988
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Interactions between fission yeast Cdk9, its cyclin partner Pch1, and mRNA capping enzyme Pct1 suggest an elongation checkpoint for mRNA quality control.

Pei Y, Schwer B, Shuman S.

J Biol Chem. 2003 Feb 28;278(9):7180-8. Epub 2002 Dec 9.

PMID:
12475973
[PubMed - indexed for MEDLINE]
Free Article
6.

Characterization of the Schizosaccharomyces pombe Cdk9/Pch1 protein kinase: Spt5 phosphorylation, autophosphorylation, and mutational analysis.

Pei Y, Shuman S.

J Biol Chem. 2003 Oct 31;278(44):43346-56. Epub 2003 Aug 5.

PMID:
12904290
[PubMed - indexed for MEDLINE]
Free Article
7.

TFIIH and P-TEFb coordinate transcription with capping enzyme recruitment at specific genes in fission yeast.

Viladevall L, St Amour CV, Rosebrock A, Schneider S, Zhang C, Allen JJ, Shokat KM, Schwer B, Leatherwood JK, Fisher RP.

Mol Cell. 2009 Mar 27;33(6):738-51. doi: 10.1016/j.molcel.2009.01.029.

PMID:
19328067
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Separable functions of the fission yeast Spt5 carboxyl-terminal domain (CTD) in capping enzyme binding and transcription elongation overlap with those of the RNA polymerase II CTD.

Schneider S, Pei Y, Shuman S, Schwer B.

Mol Cell Biol. 2010 May;30(10):2353-64. doi: 10.1128/MCB.00116-10. Epub 2010 Mar 15.

PMID:
20231361
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Control of transcriptional elongation and cotranscriptional histone modification by the yeast BUR kinase substrate Spt5.

Zhou K, Kuo WH, Fillingham J, Greenblatt JF.

Proc Natl Acad Sci U S A. 2009 Apr 28;106(17):6956-61. doi: 10.1073/pnas.0806302106. Epub 2009 Apr 13.

PMID:
19365074
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Transcription factor IIS cooperates with the E3 ligase UBR5 to ubiquitinate the CDK9 subunit of the positive transcription elongation factor B.

Cojocaru M, Bouchard A, Cloutier P, Cooper JJ, Varzavand K, Price DH, Coulombe B.

J Biol Chem. 2011 Feb 18;286(7):5012-22. doi: 10.1074/jbc.M110.176628. Epub 2010 Dec 2.

PMID:
21127351
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Insights into the function of the human P-TEFb component CDK9 in the regulation of chromatin modifications and co-transcriptional mRNA processing.

Pirngruber J, Shchebet A, Johnsen SA.

Cell Cycle. 2009 Nov 15;8(22):3636-42. Epub 2009 Nov 24. Review.

PMID:
19844166
[PubMed - indexed for MEDLINE]
Free Article
12.

Coordination of transcription factor phosphorylation and histone methylation by the P-TEFb kinase during human immunodeficiency virus type 1 transcription.

Zhou M, Deng L, Lacoste V, Park HU, Pumfery A, Kashanchi F, Brady JN, Kumar A.

J Virol. 2004 Dec;78(24):13522-33.

PMID:
15564463
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Phosphorylation by cyclin-dependent kinase-9 controls ubiquitin-conjugating enzyme-2A function.

Shchebet A, Karpiuk O, Kremmer E, Eick D, Johnsen SA.

Cell Cycle. 2012 Jun 1;11(11):2122-7. doi: 10.4161/cc.20548. Epub 2012 Jun 1.

PMID:
22592529
[PubMed - indexed for MEDLINE]
14.

Phosphorylation of the transcription elongation factor Spt5 by yeast Bur1 kinase stimulates recruitment of the PAF complex.

Liu Y, Warfield L, Zhang C, Luo J, Allen J, Lang WH, Ranish J, Shokat KM, Hahn S.

Mol Cell Biol. 2009 Sep;29(17):4852-63. doi: 10.1128/MCB.00609-09. Epub 2009 Jul 6.

PMID:
19581288
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Structural basis for Spt5-mediated recruitment of the Paf1 complex to chromatin.

Wier AD, Mayekar MK, Héroux A, Arndt KM, VanDemark AP.

Proc Natl Acad Sci U S A. 2013 Oct 22;110(43):17290-5. doi: 10.1073/pnas.1314754110. Epub 2013 Oct 7.

PMID:
24101474
[PubMed - indexed for MEDLINE]
Free PMC Article
16.
17.

Mechanisms controlling CDK9 activity.

Marshall RM, Grana X.

Front Biosci. 2006 Sep 1;11:2598-613. Review.

PMID:
16720337
[PubMed - indexed for MEDLINE]
18.

G-actin participates in RNA polymerase II-dependent transcription elongation by recruiting positive transcription elongation factor b (P-TEFb).

Qi T, Tang W, Wang L, Zhai L, Guo L, Zeng X.

J Biol Chem. 2011 Apr 29;286(17):15171-81. doi: 10.1074/jbc.M110.184374. Epub 2011 Mar 4.

PMID:
21378166
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

How an mRNA capping enzyme reads distinct RNA polymerase II and Spt5 CTD phosphorylation codes.

Doamekpor SK, Sanchez AM, Schwer B, Shuman S, Lima CD.

Genes Dev. 2014 Jun 15;28(12):1323-36. doi: 10.1101/gad.242768.114.

PMID:
24939935
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Cdk9 is an essential kinase in Drosophila that is required for heat shock gene expression, histone methylation and elongation factor recruitment.

Eissenberg JC, Shilatifard A, Dorokhov N, Michener DE.

Mol Genet Genomics. 2007 Feb;277(2):101-14. Epub 2006 Sep 26.

PMID:
17001490
[PubMed - indexed for MEDLINE]

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