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D-dimer levels over time and the risk of recurrent venous thromboembolism: an update of the Vienna prediction model.

Eichinger S, Heinze G, Kyrle PA.

J Am Heart Assoc. 2014 Jan 2;3(1):e000467. doi: 10.1161/JAHA.113.000467.


Patient-level meta-analysis: effect of measurement timing, threshold, and patient age on ability of D-dimer testing to assess recurrence risk after unprovoked venous thromboembolism.

Douketis J, Tosetto A, Marcucci M, Baglin T, Cushman M, Eichinger S, Palareti G, Poli D, Tait RC, Iorio A.

Ann Intern Med. 2010 Oct 19;153(8):523-31. doi: 10.7326/0003-4819-153-8-201010190-00009. Review.


Residual venous obstruction, alone and in combination with D-dimer, as a risk factor for recurrence after anticoagulation withdrawal following a first idiopathic deep vein thrombosis in the prolong study.

Cosmi B, Legnani C, Iorio A, Pengo V, Ghirarduzzi A, Testa S, Poli D, Tripodi A, Palareti G; PROLONG Investigators (on behalf of FCSA, Italian Federation of Anticoagulation Clinics).

Eur J Vasc Endovasc Surg. 2010 Mar;39(3):356-65. doi: 10.1016/j.ejvs.2009.11.022. Epub 2010 Jan 19.


Predicting disease recurrence in patients with previous unprovoked venous thromboembolism: a proposed prediction score (DASH).

Tosetto A, Iorio A, Marcucci M, Baglin T, Cushman M, Eichinger S, Palareti G, Poli D, Tait RC, Douketis J.

J Thromb Haemost. 2012 Jun;10(6):1019-25. doi: 10.1111/j.1538-7836.2012.04735.x.


Risk of recurrence in patients with pulmonary embolism: predictive role of D-dimer and of residual perfusion defects on lung scintigraphy.

Poli D, Cenci C, Antonucci E, Grifoni E, Arcangeli C, Prisco D, Abbate R, Miniati M.

Thromb Haemost. 2013 Feb;109(2):181-6. doi: 10.1160/TH12-07-0534. Epub 2012 Nov 29.


D-dimer testing to select patients with a first unprovoked venous thromboembolism who can stop anticoagulant therapy: a cohort study.

Kearon C, Spencer FA, O'Keeffe D, Parpia S, Schulman S, Baglin T, Stevens SM, Kaatz S, Bauer KA, Douketis JD, Lentz SR, Kessler CM, Moll S, Connors JM, Ginsberg JS, Spadafora L, Julian JA; D-dimer Optimal Duration Study Investigators.

Ann Intern Med. 2015 Jan 6;162(1):27-34. doi: 10.7326/M14-1275.


Risk assessment of recurrence in patients with unprovoked deep vein thrombosis or pulmonary embolism: the Vienna prediction model.

Eichinger S, Heinze G, Jandeck LM, Kyrle PA.

Circulation. 2010 Apr 13;121(14):1630-6. doi: 10.1161/CIRCULATIONAHA.109.925214. Epub 2010 Mar 29.


Predicting the risk of recurrent venous thromboembolism. The Austrian study on recurrent venous thromboembolism (AUREC).

Kyrle PA, Eischer L.

Hamostaseologie. 2013 Aug 1;33(3):201-9. doi: 10.5482/HAMO-13-03-0018. Epub 2013 May 27.


Systematic review: D-dimer to predict recurrent disease after stopping anticoagulant therapy for unprovoked venous thromboembolism.

Verhovsek M, Douketis JD, Yi Q, Shrivastava S, Tait RC, Baglin T, Poli D, Lim W.

Ann Intern Med. 2008 Oct 7;149(7):481-90, W94. Review.


Venous thromboembolism: risk factors for recurrence.

Zhu T, Martinez I, Emmerich J.

Arterioscler Thromb Vasc Biol. 2009 Mar;29(3):298-310. doi: 10.1161/ATVBAHA.108.182428. Review.


D-dimer and prothrombin fragment 1 + 2 predict venous thromboembolism in patients with cancer: results from the Vienna Cancer and Thrombosis Study.

Ay C, Vormittag R, Dunkler D, Simanek R, Chiriac AL, Drach J, Quehenberger P, Wagner O, Zielinski C, Pabinger I.

J Clin Oncol. 2009 Sep 1;27(25):4124-9. doi: 10.1200/JCO.2008.21.7752. Epub 2009 Jul 27.


Inflammatory bowel disease is a risk factor for recurrent venous thromboembolism.

Novacek G, Weltermann A, Sobala A, Tilg H, Petritsch W, Reinisch W, Mayer A, Haas T, Kaser A, Feichtenschlager T, Fuchssteiner H, Knoflach P, Vogelsang H, Miehsler W, Platzer R, Tillinger W, Jaritz B, Schmid A, Blaha B, Dejaco C, Eichinger S.

Gastroenterology. 2010 Sep;139(3):779-87, 787.e1. doi: 10.1053/j.gastro.2010.05.026. Epub 2010 Jun 12.


D-dimer levels and risk of recurrent venous thromboembolism.

Eichinger S, Minar E, Bialonczyk C, Hirschl M, Quehenberger P, Schneider B, Weltermann A, Wagner O, Kyrle PA.

JAMA. 2003 Aug 27;290(8):1071-4.


D-dimer to guide the duration of anticoagulation in patients with venous thromboembolism: a management study.

Palareti G, Cosmi B, Legnani C, Antonucci E, De Micheli V, Ghirarduzzi A, Poli D, Testa S, Tosetto A, Pengo V, Prandoni P; DULCIS (D-dimer and ULtrasonography in Combination Italian Study) Investigators.

Blood. 2014 Jul 10;124(2):196-203. doi: 10.1182/blood-2014-01-548065. Epub 2014 May 30.


Treatment of DVT: how long is enough and how do you predict recurrence.

Agnelli G, Becattini C.

J Thromb Thrombolysis. 2008 Feb;25(1):37-44. Epub 2007 Oct 1. Review.


D-dimer, factor VIII coagulant activity, low-intensity warfarin and the risk of recurrent venous thromboembolism.

Shrivastava S, Ridker PM, Glynn RJ, Goldhaber SZ, Moll S, Bounameaux H, Bauer KA, Kessler CM, Cushman M.

J Thromb Haemost. 2006 Jun;4(6):1208-14.


Optimal duration of anticoagulation. Provoked versus unprovoked VTE and role of adjunctive thrombophilia and imaging tests.

Prandoni P, Barbar S, Milan M, Campello E, Spiezia L, Piovella C, Pesavento R.

Thromb Haemost. 2015 Jun;113(6):1210-5. doi: 10.1160/TH14-04-0396. Epub 2014 Aug 14. Review.


The negative predictive value of D-dimer on the risk of recurrent venous thromboembolism in patients with multiple previous events: a prospective cohort study (the PROLONG PLUS study).

Ageno W, Cosmi B, Ghirarduzzi A, Santoro R, Bucherini E, Poli D, Prisco D, Alatri A, Pengo V, Galli L, Dentali F, Palareti G.

Am J Hematol. 2012 Jul;87(7):713-5. doi: 10.1002/ajh.23198. Epub 2012 Apr 10.


Predictive value of D-dimer test for recurrent venous thromboembolism after anticoagulation withdrawal in subjects with a previous idiopathic event and in carriers of congenital thrombophilia.

Palareti G, Legnani C, Cosmi B, Valdré L, Lunghi B, Bernardi F, Coccheri S.

Circulation. 2003 Jul 22;108(3):313-8. Epub 2003 Jul 7.

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