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Dysregulation of human apurinic/apyrimidinic endonuclease 1 (APE1) expression in advanced retinoblastoma.

Sudhakar J, Khetan V, Madhusudan S, Krishnakumar S.

Br J Ophthalmol. 2014 Mar;98(3):402-7. doi: 10.1136/bjophthalmol-2013-304166. Epub 2014 Jan 2.


Human apurinic/apyrimidinic endonuclease (APE1) is a prognostic factor in ovarian, gastro-oesophageal and pancreatico-biliary cancers.

Al-Attar A, Gossage L, Fareed KR, Shehata M, Mohammed M, Zaitoun AM, Soomro I, Lobo DN, Abbotts R, Chan S, Madhusudan S.

Br J Cancer. 2010 Feb 16;102(4):704-9. doi: 10.1038/sj.bjc.6605541. Epub 2010 Jan 19.


Human apurinic/apyrimidinic endonuclease siRNA inhibits the angiogenesis induced by X-ray irradiation in lung cancer cells.

Gu X, Cun Y, Li M, Qing Y, Jin F, Zhong Z, Dai N, Qian C, Sui J, Wang D.

Int J Med Sci. 2013 May 20;10(7):870-82. doi: 10.7150/ijms.5727. Print 2013.


Apurinic/apyrimidinic endonuclease activity is associated with response to radiation and chemotherapy in medulloblastoma and primitive neuroectodermal tumors.

Bobola MS, Finn LS, Ellenbogen RG, Geyer JR, Berger MS, Braga JM, Meade EH, Gross ME, Silber JR.

Clin Cancer Res. 2005 Oct 15;11(20):7405-14.


Prognostic value of human apurinic/apyrimidinic endonuclease 1 (APE1) expression in breast cancer.

Woo J, Park H, Sung SH, Moon BI, Suh H, Lim W.

PLoS One. 2014 Jun 10;9(6):e99528. doi: 10.1371/journal.pone.0099528. eCollection 2014.


Apurinic apyrimidinic endonuclease/redox effector factor 1 immunoreactivity and grading in hepatocellular carcinoma risk of relapse after liver transplantation.

Avellini C, Orsaria M, Baccarani U, Adani GL, Lorenzin D, Bresadola V, Bresadola F, Beltrami CA.

Transplant Proc. 2010 May;42(4):1204-8. doi: 10.1016/j.transproceed.2010.03.045.


Clinicopathological significance of human apurinic/apyrimidinic endonuclease 1 (APE1) expression in oestrogen-receptor-positive breast cancer.

Abdel-Fatah TM, Perry C, Moseley P, Johnson K, Arora A, Chan S, Ellis IO, Madhusudan S.

Breast Cancer Res Treat. 2014 Feb;143(3):411-21. doi: 10.1007/s10549-013-2820-7. Epub 2014 Jan 1.


Downregulation of apurinic/apyrimidinic endonuclease 1/redox factor-1 enhances the sensitivity of human pancreatic cancer cells to radiotherapy in vitro.

Chen S, Xiong G, Wu S, Mo J.

Cancer Biother Radiopharm. 2013 Mar;28(2):169-76. doi: 10.1089/cbr.2012.1266. Epub 2012 Dec 26.


Alteration of AP-endonuclease1 expression in curcumin-treated fibrotic rats.

Bassiouny AR, Zaky A, Kandeel KM.

Ann Hepatol. 2011 Oct-Dec;10(4):516-30.


Expression of 8-oxoguanine DNA glycosylase (Ogg1) in mouse retina.

Bigot K, Leemput J, Vacher M, Campalans A, Radicella JP, Lacassagne E, Provost A, Masson C, Menasche M, Abitbol M.

Mol Vis. 2009 Jun 5;15:1139-52.


Subcellular localization of apurinic endonuclease 1 promotes lung tumor aggressiveness via NF-kappaB activation.

Wu HH, Cheng YW, Chang JT, Wu TC, Liu WS, Chen CY, Lee H.

Oncogene. 2010 Jul 29;29(30):4330-40. doi: 10.1038/onc.2010.178. Epub 2010 May 24.


Nuclear depletion of apurinic/apyrimidinic endonuclease 1 (Ape1/Ref-1) is an indicator of energy disruption in neurons.

Singh S, Englander EW.

Free Radic Biol Med. 2012 Nov 1;53(9):1782-90. doi: 10.1016/j.freeradbiomed.2012.07.025. Epub 2012 Jul 27.


Nm23-H1 protein binds to APE1 at AP sites and stimulates AP endonuclease activity following ionizing radiation of the human lung cancer A549 cells.

Zhang ZM, Yang XQ, Wang D, Wang G, Yang ZZ, Qing Y, Yang ZX, Li MX, Xiang DB.

Cell Biochem Biophys. 2011 Dec;61(3):561-72. doi: 10.1007/s12013-011-9238-9.


Targeting human apurinic/apyrimidinic endonuclease 1 (APE1) in phosphatase and tensin homolog (PTEN) deficient melanoma cells for personalized therapy.

Abbotts R, Jewell R, Nsengimana J, Maloney DJ, Simeonov A, Seedhouse C, Elliott F, Laye J, Walker C, Jadhav A, Grabowska A, Ball G, Patel PM, Newton-Bishop J, Wilson DM 3rd, Madhusudan S.

Oncotarget. 2014 May 30;5(10):3273-86.


Apurinic/apyrimidinic endonuclease 1 regulates angiogenesis in a transforming growth factor β-dependent manner in human osteosarcoma.

Jiang X, Shan J, Dai N, Zhong Z, Qing Y, Yang Y, Zhang S, Li C, Sui J, Ren T, Li M, Wang D.

Cancer Sci. 2015 Oct;106(10):1394-401. doi: 10.1111/cas.12763. Epub 2015 Sep 25.


Microarray analysis and biochemical correlations of oxidative stress responsive genes in retinoblastoma.

Vandhana S, Lakshmi TS, Indra D, Deepa PR, Krishnakumar S.

Curr Eye Res. 2012 Sep;37(9):830-41. doi: 10.3109/02713683.2012.678544. Epub 2012 Jun 5.


Expression pattern of apurinic/apyrimidinic endonuclease in sinonasal squamous cell carcinoma.

Lee JW, Jin J, Rha KS, Kim YM.

Otolaryngol Head Neck Surg. 2012 Oct;147(4):788-95. Epub 2012 May 29.


APE1 overexpression is associated with cisplatin resistance in non-small cell lung cancer and targeted inhibition of APE1 enhances the activity of cisplatin in A549 cells.

Wang D, Xiang DB, Yang XQ, Chen LS, Li MX, Zhong ZY, Zhang YS.

Lung Cancer. 2009 Dec;66(3):298-304. doi: 10.1016/j.lungcan.2009.02.019. Epub 2009 Mar 25.


Functional regulation of the apurinic/apyrimidinic endonuclease 1 by nucleophosmin: impact on tumor biology.

Vascotto C, Lirussi L, Poletto M, Tiribelli M, Damiani D, Fabbro D, Damante G, Demple B, Colombo E, Tell G.

Oncogene. 2014 May 29;33(22):2876-87. doi: 10.1038/onc.2013.251. Epub 2013 Jul 8. Erratum in: Oncogene. 2015 Jun;34(26):3482.

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