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Results: 1 to 20 of 93

1.

Centrosomal BRCA2 is a target protein of membrane type-1 matrix metalloproteinase (MT1-MMP).

Wali N, Hosokawa K, Malik S, Saito H, Miyaguchi K, Imajoh-Ohmi S, Miki Y, Nakanishi A.

Biochem Biophys Res Commun. 2014 Jan 24;443(4):1148-54. doi: 10.1016/j.bbrc.2013.12.103. Epub 2013 Dec 30.

PMID:
24384087
[PubMed - indexed for MEDLINE]
2.

Centrosomal pericentrin is a direct cleavage target of membrane type-1 matrix metalloproteinase in humans but not in mice: potential implications for tumorigenesis.

Golubkov VS, Chekanov AV, Doxsey SJ, Strongin AY.

J Biol Chem. 2005 Dec 23;280(51):42237-41. Epub 2005 Oct 26.

PMID:
16251193
[PubMed - indexed for MEDLINE]
Free Article
3.

Mutational and structural analyses of the hinge region of membrane type 1-matrix metalloproteinase and enzyme processing.

Osenkowski P, Meroueh SO, Pavel D, Mobashery S, Fridman R.

J Biol Chem. 2005 Jul 15;280(28):26160-8. Epub 2005 May 18.

PMID:
15901740
[PubMed - indexed for MEDLINE]
Free Article
4.

Membrane type 1 matrix metalloproteinase (MT1-MMP/MMP-14) cleaves and releases a 22-kDa extracellular matrix metalloproteinase inducer (EMMPRIN) fragment from tumor cells.

Egawa N, Koshikawa N, Tomari T, Nabeshima K, Isobe T, Seiki M.

J Biol Chem. 2006 Dec 8;281(49):37576-85. Epub 2006 Oct 18.

PMID:
17050542
[PubMed - indexed for MEDLINE]
Free Article
5.

Internal cleavages of the autoinhibitory prodomain are required for membrane type 1 matrix metalloproteinase activation, although furin cleavage alone generates inactive proteinase.

Golubkov VS, Cieplak P, Chekanov AV, Ratnikov BI, Aleshin AE, Golubkova NV, Postnova TI, Radichev IA, Rozanov DV, Zhu W, Motamedchaboki K, Strongin AY.

J Biol Chem. 2010 Sep 3;285(36):27726-36. doi: 10.1074/jbc.M110.135442. Epub 2010 Jul 6.

PMID:
20605791
[PubMed - indexed for MEDLINE]
Free PMC Article
6.
7.

Membrane type-1 matrix metalloproteinase (MT1-MMP) exhibits an important intracellular cleavage function and causes chromosome instability.

Golubkov VS, Boyd S, Savinov AY, Chekanov AV, Osterman AL, Remacle A, Rozanov DV, Doxsey SJ, Strongin AY.

J Biol Chem. 2005 Jul 1;280(26):25079-86. Epub 2005 May 4.

PMID:
15878869
[PubMed - indexed for MEDLINE]
Free Article
8.

A CRM1-mediated nuclear export signal governs cytoplasmic localization of BRCA2 and is essential for centrosomal localization of BRCA2.

Han X, Saito H, Miki Y, Nakanishi A.

Oncogene. 2008 May 8;27(21):2969-77. Epub 2007 Dec 3.

PMID:
18059333
[PubMed - indexed for MEDLINE]
9.

Identification and characterization of Lutheran blood group glycoprotein as a new substrate of membrane-type 1 matrix metalloproteinase 1 (MT1-MMP): a systemic whole cell analysis of MT1-MMP-associating proteins in A431 cells.

Niiya D, Egawa N, Sakamoto T, Kikkawa Y, Shinkawa T, Isobe T, Koshikawa N, Seiki M.

J Biol Chem. 2009 Oct 2;284(40):27360-9. doi: 10.1074/jbc.M109.029124. Epub 2009 Aug 10.

PMID:
19667067
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Intradomain cleavage of inhibitory prodomain is essential to protumorigenic function of membrane type-1 matrix metalloproteinase (MT1-MMP) in vivo.

Golubkov VS, Chernov AV, Strongin AY.

J Biol Chem. 2011 Sep 30;286(39):34215-23. doi: 10.1074/jbc.M111.264036. Epub 2011 Aug 8.

PMID:
21832072
[PubMed - indexed for MEDLINE]
Free PMC Article
11.
12.

Interference with BRCA2, which localizes to the centrosome during S and early M phase, leads to abnormal nuclear division.

Nakanishi A, Han X, Saito H, Taguchi K, Ohta Y, Imajoh-Ohmi S, Miki Y.

Biochem Biophys Res Commun. 2007 Mar 30;355(1):34-40. Epub 2007 Jan 26.

PMID:
17286961
[PubMed - indexed for MEDLINE]
13.

The Wnt/planar cell polarity protein-tyrosine kinase-7 (PTK7) is a highly efficient proteolytic target of membrane type-1 matrix metalloproteinase: implications in cancer and embryogenesis.

Golubkov VS, Chekanov AV, Cieplak P, Aleshin AE, Chernov AV, Zhu W, Radichev IA, Zhang D, Dong PD, Strongin AY.

J Biol Chem. 2010 Nov 12;285(46):35740-9. doi: 10.1074/jbc.M110.165159. Epub 2010 Sep 13.

PMID:
20837484
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Membrane type 1 matrix metalloproteinase (MT1-MMP) ubiquitination at Lys581 increases cellular invasion through type I collagen.

Eisenach PA, de Sampaio PC, Murphy G, Roghi C.

J Biol Chem. 2012 Mar 30;287(14):11533-45. doi: 10.1074/jbc.M111.306340. Epub 2012 Feb 7.

PMID:
22315223
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Caveolin-1 inhibits membrane-type 1 matrix metalloproteinase activity.

Kim HN, Chung HS.

BMB Rep. 2008 Dec 31;41(12):858-62.

PMID:
19123976
[PubMed - indexed for MEDLINE]
Free Article
16.

Membrane localization of membrane type 1 matrix metalloproteinase by CD44 regulates the activation of pro-matrix metalloproteinase 9 in osteoclasts.

Chellaiah MA, Ma T.

Biomed Res Int. 2013;2013:302392. doi: 10.1155/2013/302392. Epub 2013 Jul 28.

PMID:
23984338
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

EphA2 cleavage by MT1-MMP triggers single cancer cell invasion via homotypic cell repulsion.

Sugiyama N, Gucciardo E, Tatti O, Varjosalo M, Hyytiäinen M, Gstaiger M, Lehti K.

J Cell Biol. 2013 Apr 29;201(3):467-84. doi: 10.1083/jcb.201205176.

PMID:
23629968
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Phosphorylation of membrane type 1-matrix metalloproteinase (MT1-MMP) and its vesicle-associated membrane protein 7 (VAMP7)-dependent trafficking facilitate cell invasion and migration.

Williams KC, Coppolino MG.

J Biol Chem. 2011 Dec 16;286(50):43405-16. doi: 10.1074/jbc.M111.297069. Epub 2011 Oct 14.

PMID:
22002060
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Tissue inhibitor of metalloproteinases-2 binding to membrane-type 1 matrix metalloproteinase induces MAPK activation and cell growth by a non-proteolytic mechanism.

D'Alessio S, Ferrari G, Cinnante K, Scheerer W, Galloway AC, Roses DF, Rozanov DV, Remacle AG, Oh ES, Shiryaev SA, Strongin AY, Pintucci G, Mignatti P.

J Biol Chem. 2008 Jan 4;283(1):87-99. Epub 2007 Nov 8.

PMID:
17991754
[PubMed - indexed for MEDLINE]
Free Article

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