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Items: 1 to 20 of 90

1.

G-protein-coupled receptors for free fatty acids: nutritional and therapeutic targets.

Milligan G, Ulven T, Murdoch H, Hudson BD.

Br J Nutr. 2014 Jun;111 Suppl 1:S3-7. doi: 10.1017/S0007114513002249. Epub 2014 Jan 2.

PMID:
24382058
2.

Drugs or diet?--Developing novel therapeutic strategies targeting the free fatty acid family of GPCRs.

Dranse HJ, Kelly ME, Hudson BD.

Br J Pharmacol. 2013 Oct;170(4):696-711. doi: 10.1111/bph.12327. Review.

3.

Experimental challenges to targeting poorly characterized GPCRs: uncovering the therapeutic potential for free fatty acid receptors.

Hudson BD, Smith NJ, Milligan G.

Adv Pharmacol. 2011;62:175-218. doi: 10.1016/B978-0-12-385952-5.00006-3. Review.

PMID:
21907910
4.

G protein-coupled receptors for free fatty acids.

Milligan G, Stoddart LA, Brown AJ.

Cell Signal. 2006 Sep;18(9):1360-5. Epub 2006 Mar 30. Review.

PMID:
16716567
5.

Free fatty acid receptor family: novel targets for the treatment of diabetes and dyslipidemia.

Bernard J.

Curr Opin Investig Drugs. 2008 Oct;9(10):1078-83. Review.

PMID:
18821469
6.

The therapeutic potential of allosteric ligands for free fatty acid sensitive GPCRs.

Hudson BD, Ulven T, Milligan G.

Curr Top Med Chem. 2013;13(1):14-25. Review.

PMID:
23409763
7.

Role of free fatty acid receptors in the regulation of energy metabolism.

Hara T, Kashihara D, Ichimura A, Kimura I, Tsujimoto G, Hirasawa A.

Biochim Biophys Acta. 2014 Sep;1841(9):1292-300. doi: 10.1016/j.bbalip.2014.06.002. Epub 2014 Jun 10. Review.

PMID:
24923869
8.

G protein-coupled receptors as regulators of glucose homeostasis and therapeutic targets for diabetes mellitus.

Tao YX, Liang XF.

Prog Mol Biol Transl Sci. 2014;121:1-21. doi: 10.1016/B978-0-12-800101-1.00001-6. Review.

PMID:
24373233
9.

Targeting GPR120 and other fatty acid-sensing GPCRs ameliorates insulin resistance and inflammatory diseases.

Talukdar S, Olefsky JM, Osborn O.

Trends Pharmacol Sci. 2011 Sep;32(9):543-50. doi: 10.1016/j.tips.2011.04.004. Epub 2011 Jun 12. Review.

10.

New frontiers in gut nutrient sensor research: free fatty acid sensing in the gastrointestinal tract.

Miyauchi S, Hirasawa A, Ichimura A, Hara T, Tsujimoto G.

J Pharmacol Sci. 2010;112(1):19-24. Review.

11.

Molecular pharmacology of promiscuous seven transmembrane receptors sensing organic nutrients.

Wellendorph P, Johansen LD, Bräuner-Osborne H.

Mol Pharmacol. 2009 Sep;76(3):453-65. doi: 10.1124/mol.109.055244. Epub 2009 Jun 1. Review.

12.

Agonism and allosterism: the pharmacology of the free fatty acid receptors FFA2 and FFA3.

Milligan G, Stoddart LA, Smith NJ.

Br J Pharmacol. 2009 Sep;158(1):146-53. doi: 10.1111/j.1476-5381.2009.00421.x. Review.

13.

Fatty acid binding receptors and their physiological role in type 2 diabetes.

Swaminath G.

Arch Pharm (Weinheim). 2008 Dec;341(12):753-61. doi: 10.1002/ardp.200800096. Review.

PMID:
19009545
14.

Fatty acid receptors as new therapeutic targets for diabetes.

Rayasam GV, Tulasi VK, Davis JA, Bansal VS.

Expert Opin Ther Targets. 2007 May;11(5):661-71. Review.

PMID:
17465724
15.

Physiology and therapeutics of the free fatty acid receptor GPR40.

Huang H, Dai MH, Tao YX.

Prog Mol Biol Transl Sci. 2014;121:67-94. doi: 10.1016/B978-0-12-800101-1.00003-X. Review.

PMID:
24373235
16.

The role of G-protein-coupled receptors in mediating the effect of fatty acids on inflammation and insulin sensitivity.

Oh DY, Lagakos WS.

Curr Opin Clin Nutr Metab Care. 2011 Jul;14(4):322-7. doi: 10.1097/MCO.0b013e3283479230. Review.

PMID:
21587066
17.

Free fatty acid receptors and their role in regulation of energy metabolism.

Hara T, Kimura I, Inoue D, Ichimura A, Hirasawa A.

Rev Physiol Biochem Pharmacol. 2013;164:77-116. doi: 10.1007/112_2013_13. Review.

PMID:
23625068
18.

Free fatty acids-sensing G protein-coupled receptors in drug targeting and therapeutics.

Yonezawa T, Kurata R, Yoshida K, Murayama MA, Cui X, Hasegawa A.

Curr Med Chem. 2013;20(31):3855-71. Review.

PMID:
23862620
19.

Free fatty acid (FFA) and hydroxy carboxylic acid (HCA) receptors.

Offermanns S.

Annu Rev Pharmacol Toxicol. 2014;54:407-34. doi: 10.1146/annurev-pharmtox-011613-135945. Epub 2013 Oct 16. Review.

PMID:
24160702
20.

The dual role of free fatty acid signaling in inflammation and therapeutics.

Volpe CM, Nogueira-Machado JA.

Recent Pat Endocr Metab Immune Drug Discov. 2013 Sep;7(3):189-97.

PMID:
23909843
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