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Items: 1 to 20 of 125

1.

Histopathological and immunohistochemical evaluation of nitrogen mustard-induced cutaneous effects in SKH-1 hairless and C57BL/6 mice.

Jain AK, Tewari-Singh N, Inturi S, Orlicky DJ, White CW, Agarwal R.

Exp Toxicol Pathol. 2014 Mar;66(2-3):129-38. doi: 10.1016/j.etp.2013.11.005. Epub 2013 Dec 25.

2.

Cutaneous injury-related structural changes and their progression following topical nitrogen mustard exposure in hairless and haired mice.

Tewari-Singh N, Jain AK, Orlicky DJ, White CW, Agarwal R.

PLoS One. 2014 Jan 8;9(1):e85402. doi: 10.1371/journal.pone.0085402. eCollection 2014.

3.

2-Chloroethyl ethyl sulfide causes microvesication and inflammation-related histopathological changes in male hairless mouse skin.

Jain AK, Tewari-Singh N, Orlicky DJ, White CW, Agarwal R.

Toxicology. 2011 Apr 11;282(3):129-38. doi: 10.1016/j.tox.2011.01.021. Epub 2011 Feb 2.

4.

Clinically-relevant cutaneous lesions by nitrogen mustard: useful biomarkers of vesicants skin injury in SKH-1 hairless and C57BL/6 mice.

Tewari-Singh N, Jain AK, Inturi S, White CW, Agarwal R.

PLoS One. 2013 Jun 24;8(6):e67557. doi: 10.1371/journal.pone.0067557. Print 2013.

5.

Absence of a p53 allele delays nitrogen mustard-induced early apoptosis and inflammation of murine skin.

Inturi S, Tewari-Singh N, Jain AK, Roy S, White CW, Agarwal R.

Toxicology. 2013 Sep 15;311(3):184-90. doi: 10.1016/j.tox.2013.06.013. Epub 2013 Jul 8.

6.

Flavanone silibinin treatment attenuates nitrogen mustard-induced toxic effects in mouse skin.

Jain AK, Tewari-Singh N, Inturi S, Kumar D, Orlicky DJ, Agarwal C, White CW, Agarwal R.

Toxicol Appl Pharmacol. 2015 May 15;285(1):71-8. doi: 10.1016/j.taap.2015.03.009. Epub 2015 Mar 16.

7.

Sulfur mustard analog, 2-chloroethyl ethyl sulfide-induced skin injury involves DNA damage and induction of inflammatory mediators, in part via oxidative stress, in SKH-1 hairless mouse skin.

Jain AK, Tewari-Singh N, Gu M, Inturi S, White CW, Agarwal R.

Toxicol Lett. 2011 Sep 10;205(3):293-301. doi: 10.1016/j.toxlet.2011.06.019. Epub 2011 Jun 21.

8.

Myeloperoxidase deficiency attenuates nitrogen mustard-induced skin injuries.

Jain AK, Tewari-Singh N, Inturi S, Orlicky DJ, White CW, Agarwal R.

Toxicology. 2014 Jun 5;320:25-33. doi: 10.1016/j.tox.2014.02.013. Epub 2014 Mar 12.

9.

Inflammatory biomarkers of sulfur mustard analog 2-chloroethyl ethyl sulfide-induced skin injury in SKH-1 hairless mice.

Tewari-Singh N, Rana S, Gu M, Pal A, Orlicky DJ, White CW, Agarwal R.

Toxicol Sci. 2009 Mar;108(1):194-206. doi: 10.1093/toxsci/kfn261. Epub 2008 Dec 15.

10.

Topical nitrogen mustard exposure causes systemic toxic effects in mice.

Goswami DG, Kumar D, Tewari-Singh N, Orlicky DJ, Jain AK, Kant R, Rancourt RC, Dhar D, Inturi S, Agarwal C, White CW, Agarwal R.

Exp Toxicol Pathol. 2015 Feb;67(2):161-70. doi: 10.1016/j.etp.2014.11.006. Epub 2014 Dec 4.

11.

Catalytic antioxidant AEOL 10150 treatment ameliorates sulfur mustard analog 2-chloroethyl ethyl sulfide-associated cutaneous toxic effects.

Tewari-Singh N, Inturi S, Jain AK, Agarwal C, Orlicky DJ, White CW, Agarwal R, Day BJ.

Free Radic Biol Med. 2014 Jul;72:285-95. doi: 10.1016/j.freeradbiomed.2014.04.022. Epub 2014 May 9.

12.

Structural changes in the skin of hairless mice following exposure to sulfur mustard correlate with inflammation and DNA damage.

Joseph LB, Gerecke DR, Heck DE, Black AT, Sinko PJ, Cervelli JA, Casillas RP, Babin MC, Laskin DL, Laskin JD.

Exp Mol Pathol. 2011 Oct;91(2):515-27. doi: 10.1016/j.yexmp.2011.05.010. Epub 2011 Jun 13.

13.

Silibinin attenuates sulfur mustard analog-induced skin injury by targeting multiple pathways connecting oxidative stress and inflammation.

Tewari-Singh N, Jain AK, Inturi S, Agarwal C, White CW, Agarwal R.

PLoS One. 2012;7(9):e46149. doi: 10.1371/journal.pone.0046149. Epub 2012 Sep 27.

14.

Evaluation of neutralized chemical agent identification sets (CAIS) for skin injury with an overview of the vesicant potential of agent degradation products.

Olajos EJ, Olson CT, Salem H, Singer AW, Hayes TL, Menton RG, Miller TL, Rosso T, MacIver B.

J Appl Toxicol. 1998 Nov-Dec;18(6):409-20.

PMID:
9840748
15.

Cutaneous challenge with chemical warfare agents in the SKH-1 hairless mouse. (I) Development of a model for screening studies in skin decontamination and protection.

Dorandeu F, Taysse L, Boudry I, Foquin A, Hérodin F, Mathieu J, Daulon S, Cruz C, Lallement G.

Hum Exp Toxicol. 2011 Jun;30(6):470-90. doi: 10.1177/0960327110373615. Epub 2010 Jun 14.

PMID:
20547654
16.

Activation of DNA damage repair pathways in response to nitrogen mustard-induced DNA damage and toxicity in skin keratinocytes.

Inturi S, Tewari-Singh N, Agarwal C, White CW, Agarwal R.

Mutat Res. 2014 May-Jun;763-764:53-63. doi: 10.1016/j.mrfmmm.2014.04.002. Epub 2014 Apr 13.

17.

Acute and long-term transcriptional responses in sulfur mustard-exposed SKH-1 hairless mouse skin.

Vallet V, Poyot T, Cléry-Barraud C, Coulon D, Sentenac C, Peinnequin A, Boudry I.

Cutan Ocul Toxicol. 2012 Mar;31(1):38-47. doi: 10.3109/15569527.2011.609206. Epub 2011 Sep 23.

PMID:
21939433
18.

Silibinin, dexamethasone, and doxycycline as potential therapeutic agents for treating vesicant-inflicted ocular injuries.

Tewari-Singh N, Jain AK, Inturi S, Ammar DA, Agarwal C, Tyagi P, Kompella UB, Enzenauer RW, Petrash JM, Agarwal R.

Toxicol Appl Pharmacol. 2012 Oct 1;264(1):23-31. doi: 10.1016/j.taap.2012.07.014. Epub 2012 Jul 24.

19.

Efficacy of glutathione in ameliorating sulfur mustard analog-induced toxicity in cultured skin epidermal cells and in SKH-1 mouse skin in vivo.

Tewari-Singh N, Agarwal C, Huang J, Day BJ, White CW, Agarwal R.

J Pharmacol Exp Ther. 2011 Feb;336(2):450-9. doi: 10.1124/jpet.110.173708. Epub 2010 Oct 25. Review.

20.

Sulfur mustard cutaneous injury characterization based on SKH-1 mouse model: relevance of non-invasive methods in terms of wound healing process analyses.

Cléry-Barraud C, Nguon N, Vallet V, Sentenac C, Four E, Arlaud C, Coulon D, Boudry I.

Skin Res Technol. 2013 Feb;19(1):e146-56. doi: 10.1111/j.1600-0846.2012.00621.x. Epub 2012 Jun 29.

PMID:
22741598
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