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Patients with single distal MCA perfusion lesions have a high rate of good outcome with or without reperfusion.

Lemmens R, Christensen S, Straka M, De Silva DA, Mlynash M, Campbell BC, Bammer R, Olivot JM, Desmond P, Marks MP, Davis SM, Donnan GA, Albers GW, Lansberg MG.

Int J Stroke. 2014 Feb;9(2):156-9. doi: 10.1111/ijs.12230. Epub 2013 Dec 23.


The association between lesion location and functional outcome after ischemic stroke.

Yassi N, Churilov L, Campbell BC, Sharma G, Bammer R, Desmond PM, Parsons MW, Albers GW, Donnan GA, Davis SM; EPITHET, and DEFUSE Investigators.

Int J Stroke. 2015 Jun 4. doi: 10.1111/ijs.12537. [Epub ahead of print]


Lesion patterns of single small subcortical infarct and its association with early neurological deterioration.

Duan Z, Fu C, Chen B, Xu G, Tao L, Tang T, Hou H, Fu X, Yang M, Liu Z, Zhang X.

Neurol Sci. 2015 Jun 2. [Epub ahead of print]


The growth rate of early DWI lesions is highly variable and associated with penumbral salvage and clinical outcomes following endovascular reperfusion.

Wheeler HM, Mlynash M, Inoue M, Tipirnini A, Liggins J, Bammer R, Lansberg MG, Kemp S, Zaharchuk G, Straka M, Albers GW; DEFUSE 2 Investigators.

Int J Stroke. 2015 Jul;10(5):723-9. doi: 10.1111/ijs.12436. Epub 2015 Jan 12.


Collateral vessels in proximal middle cerebral artery occlusion: the ENDOSTROKE study.

Singer OC, Berkefeld J, Nolte CH, Bohner G, Reich A, Wiesmann M, Groeschel K, Boor S, Neumann-Haefelin T, Hofmann E, Stoll A, Bormann A, Liebeskind DS.

Radiology. 2015 Mar;274(3):851-8. doi: 10.1148/radiol.14140951. Epub 2015 Jan 5.


Impact of time-to-reperfusion on outcome in patients with poor collaterals.

Hwang YH, Kang DH, Kim YW, Kim YS, Park SP, Liebeskind DS.

AJNR Am J Neuroradiol. 2015 Mar;36(3):495-500. doi: 10.3174/ajnr.A4151. Epub 2014 Nov 6.


Early reperfusion and clinical outcomes in patients with M2 occlusion: pooled analysis of the PROACT II, IMS, and IMS II studies.

Rahme R, Yeatts SD, Abruzzo TA, Jimenez L, Fan L, Tomsick TA, Ringer AJ, Furlan AJ, Broderick JP, Khatri P.

J Neurosurg. 2014 Dec;121(6):1354-8. doi: 10.3171/2014.7.JNS131430. Epub 2014 Sep 26.


Do FLAIR vascular hyperintensities beyond the DWI lesion represent the ischemic penumbra?

Legrand L, Tisserand M, Turc G, Naggara O, Edjlali M, Mellerio C, Mas JL, Méder JF, Baron JC, Oppenheim C.

AJNR Am J Neuroradiol. 2015 Feb;36(2):269-74. doi: 10.3174/ajnr.A4088. Epub 2014 Sep 4.


Impact of diffusion-weighted imaging Alberta stroke program early computed tomography score on the success of endovascular reperfusion therapy.

Inoue M, Olivot JM, Labreuche J, Mlynash M, Tai W, Albucher JF, Meseguer E, Amarenco P, Mazighi M.

Stroke. 2014 Jul;45(7):1992-8. doi: 10.1161/STROKEAHA.114.005084. Epub 2014 Jun 12.


The infarct location predicts the outcome of single small subcortical infarction in the territory of the middle cerebral artery.

Yang X, Pu Y, Liu L, Wang Y, Zou X, Pan Y, Wang D, Zhao X, Wong KS, Wang Y.

J Stroke Cerebrovasc Dis. 2014 Jul;23(6):1676-81. doi: 10.1016/j.jstrokecerebrovasdis.2014.01.019. Epub 2014 Apr 13.


Comparison of magnetic resonance imaging mismatch criteria to select patients for endovascular stroke therapy.

Mishra NK, Albers GW, Christensen S, Marks M, Hamilton S, Straka M, Liggins JT, Kemp S, Mlynash M, Bammer R, Lansberg MG; Diffusion and Perfusion Imaging Evaluation for Understanding Stroke Evolution 2 Investigators.

Stroke. 2014 May;45(5):1369-74. doi: 10.1161/STROKEAHA.114.004772. Epub 2014 Apr 3.


Hypoperfusion intensity ratio predicts infarct progression and functional outcome in the DEFUSE 2 Cohort.

Olivot JM, Mlynash M, Inoue M, Marks MP, Wheeler HM, Kemp S, Straka M, Zaharchuk G, Bammer R, Lansberg MG, Albers GW; DEFUSE 2 Investigators.

Stroke. 2014 Apr;45(4):1018-23. doi: 10.1161/STROKEAHA.113.003857. Epub 2014 Mar 4. Erratum in: Stroke. 2014 May;45(5):e92.


Leukoaraiosis predicts cortical infarct volume after distal middle cerebral artery occlusion.

Henninger N, Khan MA, Zhang J, Moonis M, Goddeau RP Jr.

Stroke. 2014 Mar;45(3):689-95. doi: 10.1161/STROKEAHA.113.002855. Epub 2014 Feb 12.


Correlation of AOL recanalization, TIMI reperfusion and TICI reperfusion with infarct growth and clinical outcome.

Marks MP, Lansberg MG, Mlynash M, Kemp S, McTaggart R, Zaharchuk G, Bammer R, Albers GW; DEFUSE 2 Investigators.

J Neurointerv Surg. 2014 Dec;6(10):724-8. doi: 10.1136/neurintsurg-2013-010973. Epub 2013 Dec 18.


Lesion development and reperfusion benefit in relation to vascular occlusion patterns after embolic stroke in rats.

Bouts MJ, Tiebosch IA, van der Toorn A, Hendrikse J, Dijkhuizen RM.

J Cereb Blood Flow Metab. 2014 Feb;34(2):332-8. doi: 10.1038/jcbfm.2013.202. Epub 2013 Dec 4.


Relative cerebral blood volume as a marker of durable tissue-at-risk viability in hyperacute ischemic stroke.

Cortijo E, Calleja AI, García-Bermejo P, Mulero P, Pérez-Fernández S, Reyes J, Muñoz MF, Martínez-Galdámez M, Arenillas JF.

Stroke. 2014 Jan;45(1):113-8. doi: 10.1161/STROKEAHA.113.003340. Epub 2013 Nov 26.


Admission insular infarction >25% is the strongest predictor of large mismatch loss in proximal middle cerebral artery stroke.

Kamalian S, Kemmling A, Borgie RC, Morais LT, Payabvash S, Franceschi AM, Kamalian S, Yoo AJ, Furie KL, Lev MH.

Stroke. 2013 Nov;44(11):3084-9. doi: 10.1161/STROKEAHA.113.002260. Epub 2013 Aug 29.


Perfusion MR predicts outcome in high-risk transient ischemic attack/minor stroke: a derivation-validation study.

Asdaghi N, Hill MD, Coulter JI, Butcher KS, Modi J, Qazi A, Goyal M, Demchuk AM, Coutts SB.

Stroke. 2013 Sep;44(9):2486-92. doi: 10.1161/STROKEAHA.111.000208. Epub 2013 Aug 1.


Comparison of the response to endovascular reperfusion in relation to site of arterial occlusion.

Lemmens R, Mlynash M, Straka M, Kemp S, Bammer R, Marks MP, Albers GW, Lansberg MG.

Neurology. 2013 Aug 13;81(7):614-8. doi: 10.1212/WNL.0b013e3182a08f07. Epub 2013 Jul 12.


Clinical outcomes strongly associated with the degree of reperfusion achieved in target mismatch patients: pooled data from the Diffusion and Perfusion Imaging Evaluation for Understanding Stroke Evolution studies.

Inoue M, Mlynash M, Straka M, Kemp S, Jovin TG, Tipirneni A, Hamilton SA, Marks MP, Bammer R, Lansberg MG, Albers GW; DEFUSE 1 and 2 Investigators.

Stroke. 2013 Jul;44(7):1885-90. doi: 10.1161/STROKEAHA.111.000371. Epub 2013 May 23.

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