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Results: 1 to 20 of 131

1.

Small G proteins Rac1 and Ras regulate serine/threonine protein phosphatase 5 (PP5)·extracellular signal-regulated kinase (ERK) complexes involved in the feedback regulation of Raf1.

Mazalouskas MD, Godoy-Ruiz R, Weber DJ, Zimmer DB, Honkanen RE, Wadzinski BE.

J Biol Chem. 2014 Feb 14;289(7):4219-32. doi: 10.1074/jbc.M113.518514. Epub 2013 Dec 26.

PMID:
24371145
[PubMed - indexed for MEDLINE]
2.

Cell type-specific importance of ras-c-raf complex association rate constants for MAPK signaling.

Kiel C, Serrano L.

Sci Signal. 2009 Jul 28;2(81):ra38. doi: 10.1126/scisignal.2000397.

PMID:
19638615
[PubMed - indexed for MEDLINE]
Free Article
3.

Rac-PAK signaling stimulates extracellular signal-regulated kinase (ERK) activation by regulating formation of MEK1-ERK complexes.

Eblen ST, Slack JK, Weber MJ, Catling AD.

Mol Cell Biol. 2002 Sep;22(17):6023-33.

PMID:
12167697
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Regulation of the Raf-MEK-ERK pathway by protein phosphatase 5.

von Kriegsheim A, Pitt A, Grindlay GJ, Kolch W, Dhillon AS.

Nat Cell Biol. 2006 Sep;8(9):1011-6. Epub 2006 Aug 6.

PMID:
16892053
[PubMed - indexed for MEDLINE]
5.

Ras-mutant cancer cells display B-Raf binding to Ras that activates extracellular signal-regulated kinase and is inhibited by protein kinase A phosphorylation.

Li Y, Takahashi M, Stork PJ.

J Biol Chem. 2013 Sep 20;288(38):27646-57. doi: 10.1074/jbc.M113.463067. Epub 2013 Jul 26.

PMID:
23893412
[PubMed - indexed for MEDLINE]
6.

RAF inhibitors prime wild-type RAF to activate the MAPK pathway and enhance growth.

Hatzivassiliou G, Song K, Yen I, Brandhuber BJ, Anderson DJ, Alvarado R, Ludlam MJ, Stokoe D, Gloor SL, Vigers G, Morales T, Aliagas I, Liu B, Sideris S, Hoeflich KP, Jaiswal BS, Seshagiri S, Koeppen H, Belvin M, Friedman LS, Malek S.

Nature. 2010 Mar 18;464(7287):431-5. doi: 10.1038/nature08833. Epub 2010 Feb 3.

PMID:
20130576
[PubMed - indexed for MEDLINE]
7.

PLC-γ and PI3K link cytokines to ERK activation in hematopoietic cells with normal and oncogenic Kras.

Diaz-Flores E, Goldschmidt H, Depeille P, Ng V, Akutagawa J, Krisman K, Crone M, Burgess MR, Williams O, Houseman B, Shokat K, Sampath D, Bollag G, Roose JP, Braun BS, Shannon K.

Sci Signal. 2013 Dec 3;6(304):ra105. doi: 10.1126/scisignal.2004125.

PMID:
24300897
[PubMed - indexed for MEDLINE]
8.

Functional interactions of Raf and MEK with Jun-N-terminal kinase (JNK) result in a positive feedback loop on the oncogenic Ras signaling pathway.

Adler V, Qu Y, Smith SJ, Izotova L, Pestka S, Kung HF, Lin M, Friedman FK, Chie L, Chung D, Boutjdir M, Pincus MR.

Biochemistry. 2005 Aug 16;44(32):10784-95.

PMID:
16086581
[PubMed - indexed for MEDLINE]
9.

Constitutively active Galpha16 stimulates STAT3 via a c-Src/JAK- and ERK-dependent mechanism.

Lo RK, Cheung H, Wong YH.

J Biol Chem. 2003 Dec 26;278(52):52154-65. Epub 2003 Oct 9.

PMID:
14551213
[PubMed - indexed for MEDLINE]
Free Article
10.

Regulation of mitogen-activated protein kinases in cardiac myocytes through the small G protein Rac1.

Clerk A, Pham FH, Fuller SJ, Sahai E, Aktories K, Marais R, Marshall C, Sugden PH.

Mol Cell Biol. 2001 Feb;21(4):1173-84.

PMID:
11158304
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Thrombopoietin-mediated sustained activation of extracellular signal-regulated kinase in UT7-Mpl cells requires both Ras-Raf-1- and Rap1-B-Raf-dependent pathways.

Garcia J, de Gunzburg J, Eychène A, Gisselbrecht S, Porteu F.

Mol Cell Biol. 2001 Apr;21(8):2659-70.

PMID:
11283246
[PubMed - indexed for MEDLINE]
Free PMC Article
12.
13.

Regulation of phosphorylation pathways by p21 GTPases. The p21 Ras-related Rho subfamily and its role in phosphorylation signalling pathways.

Lim L, Manser E, Leung T, Hall C.

Eur J Biochem. 1996 Dec 1;242(2):171-85. Review.

PMID:
8973630
[PubMed - indexed for MEDLINE]
Free Article
14.
15.

cAMP inhibits the proliferation of retinal pigmented epithelial cells through the inhibition of ERK1/2 in a PKA-independent manner.

Hecquet C, Lefevre G, Valtink M, Engelmann K, Mascarelli F.

Oncogene. 2002 Sep 5;21(39):6101-12.

PMID:
12203122
[PubMed - indexed for MEDLINE]
Free Article
16.

Flagellin and lipopolysaccharide stimulate the MEK-ERK signaling pathway in chicken heterophils through differential activation of the small GTPases, Ras and Rap1.

Kogut MH, Genovese KJ, He H.

Mol Immunol. 2007 Mar;44(7):1729-36. Epub 2006 Oct 12.

PMID:
17045653
[PubMed - indexed for MEDLINE]
17.

Enhanced clonogenic survival induced by protein tyrosine phosphatase (PTP) inhibition after Cr(VI) exposure is mediated by c-Raf and Ras activity.

Bae D, Camilli TC, Ha NT, Ceryak S.

Cell Signal. 2009 May;21(5):727-36. doi: 10.1016/j.cellsig.2009.01.011. Epub 2009 Jan 8.

PMID:
19167484
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Interferon-alpha2b reduces phosphorylation and activity of MEK and ERK through a Ras/Raf-independent mechanism.

Romerio F, Riva A, Zella D.

Br J Cancer. 2000 Aug;83(4):532-8.

PMID:
10945503
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Noncatalytic function of ERK1/2 can promote Raf/MEK/ERK-mediated growth arrest signaling.

Hong SK, Yoon S, Moelling C, Arthan D, Park JI.

J Biol Chem. 2009 Nov 27;284(48):33006-18. doi: 10.1074/jbc.M109.012591. Epub 2009 Oct 5.

PMID:
19805545
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Epidermal growth factor induces c-fos and c-jun mRNA via Raf-1/MEK1/ERK-dependent and -independent pathways in bovine luteal cells.

Chen DB, Davis JS.

Mol Cell Endocrinol. 2003 Feb 28;200(1-2):141-54.

PMID:
12644307
[PubMed - indexed for MEDLINE]

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