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Cytomegalovirus infection modulates the phenotype and functional profile of the T-cell immune response to mycobacterial antigens in older life.

Terrazzini N, Bajwa M, Vita S, Thomas D, Smith H, Vescovini R, Sansoni P, Kern F.

Exp Gerontol. 2014 Jun;54:94-100. doi: 10.1016/j.exger.2013.12.007. Epub 2013 Dec 25.


The phenotypic distribution and functional profile of tuberculin-specific CD4 T-cells characterizes different stages of TB infection.

Streitz M, Fuhrmann S, Thomas D, Cheek E, Nomura L, Maecker H, Martus P, Aghaeepour N, Brinkman RR, Volk HD, Kern F.

Cytometry B Clin Cytom. 2012 Nov;82(6):360-8. doi: 10.1002/cyto.b.21041. Epub 2012 Sep 7.


Persistent and selective deficiency of CD4+ T cell immunity to cytomegalovirus in immunocompetent young children.

Tu W, Chen S, Sharp M, Dekker C, Manganello AM, Tongson EC, Maecker HT, Holmes TH, Wang Z, Kemble G, Adler S, Arvin A, Lewis DB.

J Immunol. 2004 Mar 1;172(5):3260-7.


Polyfunctional T cells accumulate in large human cytomegalovirus-specific T cell responses.

Lachmann R, Bajwa M, Vita S, Smith H, Cheek E, Akbar A, Kern F.

J Virol. 2012 Jan;86(2):1001-9. doi: 10.1128/JVI.00873-11. Epub 2011 Nov 9.


Properties of CD4(+) T cells in human cytomegalovirus infection.

Gamadia LE, Rentenaar RJ, van Lier RA, ten Berge IJ.

Hum Immunol. 2004 May;65(5):486-92.


Cytomegalovirus-specific T cell immunity is maintained in immunosenescent rhesus macaques.

Cicin-Sain L, Sylwester AW, Hagen SI, Siess DC, Currier N, Legasse AW, Fischer MB, Koudelka CW, Axthelm MK, Nikolich-Zugich J, Picker LJ.

J Immunol. 2011 Aug 15;187(4):1722-32. doi: 10.4049/jimmunol.1100560. Epub 2011 Jul 15.


Analyzing T-cell responses to cytomegalovirus by cytokine flow cytometry.

Maecker HT, Maino VC.

Hum Immunol. 2004 May;65(5):493-9. Review.


Differentiation of antigen-specific T cells with limited functional capacity during Mycobacterium tuberculosis infection.

Jeong YH, Jeon BY, Gu SH, Cho SN, Shin SJ, Chang J, Ha SJ.

Infect Immun. 2014 Jan;82(1):132-9. doi: 10.1128/IAI.00480-13. Epub 2013 Oct 14. Erratum in: Infect Immun. 2014 Aug;82(8):3514.


Polyfunctional T-cells and effector memory phenotype are associated with active TB in HIV-infected patients.

Chiacchio T, Petruccioli E, Vanini V, Cuzzi G, Pinnetti C, Sampaolesi A, Antinori A, Girardi E, Goletti D.

J Infect. 2014 Dec;69(6):533-45. doi: 10.1016/j.jinf.2014.06.009. Epub 2014 Jun 26.


Protective CD4 T cells targeting cryptic epitopes of Mycobacterium tuberculosis resist infection-driven terminal differentiation.

Woodworth JS, Aagaard CS, Hansen PR, Cassidy JP, Agger EM, Andersen P.

J Immunol. 2014 Apr 1;192(7):3247-58. doi: 10.4049/jimmunol.1300283. Epub 2014 Feb 26.


Frequency of human cytomegalovirus-specific T cells during pregnancy determined by intracellular cytokine staining.

Fujikawa T, Numazaki K, Asanuma H, Kudo R, Tsutsumi H.

J Med Virol. 2003 Dec;71(4):527-31.


Cytomegalovirus (CMV)-specific cellular immune responses.

Harari A, Zimmerli SC, Pantaleo G.

Hum Immunol. 2004 May;65(5):500-6. Review.


Preferential infection and depletion of Mycobacterium tuberculosis-specific CD4 T cells after HIV-1 infection.

Geldmacher C, Ngwenyama N, Schuetz A, Petrovas C, Reither K, Heeregrave EJ, Casazza JP, Ambrozak DR, Louder M, Ampofo W, Pollakis G, Hill B, Sanga E, Saathoff E, Maboko L, Roederer M, Paxton WA, Hoelscher M, Koup RA.

J Exp Med. 2010 Dec 20;207(13):2869-81. doi: 10.1084/jem.20100090. Epub 2010 Nov 29.


IFNγ/TNFα specific-cells and effector memory phenotype associate with active tuberculosis.

Petruccioli E, Petrone L, Vanini V, Sampaolesi A, Gualano G, Girardi E, Palmieri F, Goletti D.

J Infect. 2013 Jun;66(6):475-86. doi: 10.1016/j.jinf.2013.02.004. Epub 2013 Feb 24.


Emergence of a CD4+CD28- granzyme B+, cytomegalovirus-specific T cell subset after recovery of primary cytomegalovirus infection.

van Leeuwen EM, Remmerswaal EB, Vossen MT, Rowshani AT, Wertheim-van Dillen PM, van Lier RA, ten Berge IJ.

J Immunol. 2004 Aug 1;173(3):1834-41.


Rudimentary signs of immunosenescence in Cytomegalovirus-seropositive healthy young adults.

Turner JE, Campbell JP, Edwards KM, Howarth LJ, Pawelec G, Aldred S, Moss P, Drayson MT, Burns VE, Bosch JA.

Age (Dordr). 2014 Feb;36(1):287-97. doi: 10.1007/s11357-013-9557-4. Epub 2013 Jul 12.


Acquisition of direct antiviral effector functions by CMV-specific CD4+ T lymphocytes with cellular maturation.

Casazza JP, Betts MR, Price DA, Precopio ML, Ruff LE, Brenchley JM, Hill BJ, Roederer M, Douek DC, Koup RA.

J Exp Med. 2006 Dec 25;203(13):2865-77. Epub 2006 Dec 11.


Maintenance of cytomegalovirus-specific CD4pos T-cell response in rheumatoid arthritis patients receiving anti-tumor necrosis factor treatments.

Davignon JL, Boyer JF, Jamard B, Nigon D, Constantin A, Cantagrel A.

Arthritis Res Ther. 2010;12(4):R142. doi: 10.1186/ar3083. Epub 2010 Jul 15.


Poor predictive value of cytomegalovirus (CMV)-specific T cell assays for the development of CMV retinitis in patients with AIDS.

Jacobson MA, Tan QX, Girling V, Poon C, Van Natta M, Jabs DA, Inokuma M, Maecker HT, Bredt B, Sinclair E; Studies of Ocular Complications of AIDS Research Group.

Clin Infect Dis. 2008 Feb 1;46(3):458-66. doi: 10.1086/525853.

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