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Items: 1 to 20 of 145

1.

Biological evaluation of a cytotoxic 2-substituted benzimidazole copper(II) complex: DNA damage, antiproliferation and apoptotic induction activity in human cervical cancer cells.

Qiao X, Ma ZY, Shao J, Bao WG, Xu JY, Qiang ZY, Lou JS.

Biometals. 2014 Feb;27(1):155-72. doi: 10.1007/s10534-013-9696-1. Epub 2013 Dec 25.

PMID:
24368745
2.

Ternary dinuclear copper(II) complexes of a hydroxybenzamide ligand with diimine coligands: the 5,6-dmp ligand enhances DNA binding and cleavage and induces apoptosis.

Ramakrishnan S, Shakthipriya D, Suresh E, Periasamy VS, Akbarsha MA, Palaniandavar M.

Inorg Chem. 2011 Jul 18;50(14):6458-71. doi: 10.1021/ic1024185. Epub 2011 Jun 14.

PMID:
21671566
3.

Synthesis, characterization, interaction with DNA, and cytotoxic effect in vitro of new mono- and dinuclear Pd(II) and Pt(II) complexes with benzo[d]thiazol-2-amine as the primary ligand.

Gao E, Liu L, Zhu M, Huang Y, Guan F, Gao X, Zhang M, Wang L, Zhang W, Sun Y.

Inorg Chem. 2011 Jun 6;50(11):4732-41. doi: 10.1021/ic102142j. Epub 2011 Apr 26.

PMID:
21520903
4.

Ferrocene-conjugated L-tryptophan copper(II) complexes of phenanthroline bases showing DNA photocleavage activity and cytotoxicity.

Goswami TK, Chakravarthi BV, Roy M, Karande AA, Chakravarty AR.

Inorg Chem. 2011 Sep 5;50(17):8452-64. doi: 10.1021/ic201028e. Epub 2011 Jul 28.

PMID:
21797197
5.

Cytotoxic activity, albumin and DNA binding of new copper(II) complexes with chalcone-derived thiosemicarbazones.

Da Silva JG, Recio Despaigne AA, Louro SR, Bandeira CC, Souza-Fagundes EM, Beraldo H.

Eur J Med Chem. 2013 Jul;65:415-26. doi: 10.1016/j.ejmech.2013.04.036. Epub 2013 May 16.

PMID:
23747809
6.

Induction of cell death by ternary copper(II) complexes of L-tyrosine and diimines: role of coligands on DNA binding and cleavage and anticancer activity.

Ramakrishnan S, Rajendiran V, Palaniandavar M, Periasamy VS, Srinag BS, Krishnamurthy H, Akbarsha MA.

Inorg Chem. 2009 Feb 16;48(4):1309-22. doi: 10.1021/ic801144x.

PMID:
19140687
7.

Mixed ligand copper(II) complexes of N,N-bis(benzimidazol-2-ylmethyl)amine (BBA) with diimine co-ligands: efficient chemical nuclease and protease activities and cytotoxicity.

Loganathan R, Ramakrishnan S, Suresh E, Riyasdeen A, Akbarsha MA, Palaniandavar M.

Inorg Chem. 2012 May 21;51(10):5512-32. doi: 10.1021/ic2017177. Epub 2012 May 4.

PMID:
22559171
8.
9.

Binuclear copper complexes: synthesis, X-ray structure and interaction study with nucleotide/protein by in vitro biochemical and electrochemical analysis.

Alagesan M, Bhuvanesh NS, Dharmaraj N.

Eur J Med Chem. 2014 May 6;78:281-93. doi: 10.1016/j.ejmech.2014.03.043. Epub 2014 Mar 19.

PMID:
24686015
10.

Synthesis, DNA binding, cellular DNA lesion and cytotoxicity of a series of new benzimidazole-based Schiff base copper(II) complexes.

Paul A, Anbu S, Sharma G, Kuznetsov ML, Koch B, Guedes da Silva MF, Pombeiro AJ.

Dalton Trans. 2015 Dec 14;44(46):19983-96. doi: 10.1039/c5dt02880a.

PMID:
26523453
11.

Synthesis, structure and in vitro pharmacological evaluation of a novel 2-oxo-1,2-dihydroquinoline-3-carbaldehyde (2'-methylbenzoyl) hydrazone bridged copper(II) coordination polymer.

Senthil Raja D, Ramachandran E, Bhuvanesh NS, Natarajan K.

Eur J Med Chem. 2013 Jun;64:148-59. doi: 10.1016/j.ejmech.2013.03.040. Epub 2013 Apr 2.

PMID:
23644198
12.

A tri-copper(II) complex displaying DNA-cleaving properties and antiproliferative activity against cancer cells.

Suntharalingam K, Hunt DJ, Duarte AA, White AJ, Mann DJ, Vilar R.

Chemistry. 2012 Nov 19;18(47):15133-41. doi: 10.1002/chem.201202482. Epub 2012 Oct 11.

PMID:
23059789
13.

New modulated design and synthesis of quercetin-Cu(II)/Zn(II)-Sn2(IV) scaffold as anticancer agents: in vitro DNA binding profile, DNA cleavage pathway and Topo-I activity.

Tabassum S, Zaki M, Afzal M, Arjmand F.

Dalton Trans. 2013 Jul 21;42(27):10029-41. doi: 10.1039/c3dt50646k. Epub 2013 May 29.

PMID:
23715526
14.

Anomalous behavior of pentacoordinate copper complexes of dimethylphenanthroline and derivatives of terpyridine ligands: Studies on DNA binding, cleavage and apoptotic activity.

Rajalakshmi S, Weyhermüller T, Freddy AJ, Vasanthi HR, Nair BU.

Eur J Med Chem. 2011 Feb;46(2):608-17. doi: 10.1016/j.ejmech.2010.11.041. Epub 2010 Dec 10.

PMID:
21193251
15.

Synthesis, crystal structure and antitumor effect of a novel copper(II) complex bearing zoledronic acid derivative.

Qiu L, Lv G, Guo L, Chen L, Luo S, Zou M, Lin J.

Eur J Med Chem. 2015 Jan 7;89:42-50. doi: 10.1016/j.ejmech.2014.10.028. Epub 2014 Oct 13.

PMID:
25462224
16.
17.

Copper(II/I) complexes of 5-pyridin-2-yl-[1,3]dioxolo[4,5-g]isoquinoline: synthesis, crystal structure, antitumor activity and DNA interaction.

Huang KB, Chen ZF, Liu YC, Wang M, Wei JH, Xie XL, Zhang JL, Hu K, Liang H.

Eur J Med Chem. 2013;70:640-8. doi: 10.1016/j.ejmech.2013.10.031. Epub 2013 Oct 22.

PMID:
24211640
18.
19.

Monitoring cellular uptake and cytotoxicity of copper(II) complex using a fluorescent anthracene thiosemicarbazone ligand.

Kate AN, Kumbhar AA, Khan AA, Joshi PV, Puranik VG.

Bioconjug Chem. 2014 Jan 15;25(1):102-14. doi: 10.1021/bc400385d. Epub 2013 Dec 19.

PMID:
24328322
20.
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