Format
Items per page
Sort by

Send to:

Choose Destination

Links from PubMed

Items: 1 to 20 of 162

1.

Effects of troponin T cardiomyopathy mutations on the calcium sensitivity of the regulated thin filament and the actomyosin cross-bridge kinetics of human β-cardiac myosin.

Sommese RF, Nag S, Sutton S, Miller SM, Spudich JA, Ruppel KM.

PLoS One. 2013 Dec 18;8(12):e83403. doi: 10.1371/journal.pone.0083403. eCollection 2013.

2.
3.

Familial dilated cardiomyopathy mutations uncouple troponin I phosphorylation from changes in myofibrillar Ca²⁺ sensitivity.

Memo M, Leung MC, Ward DG, dos Remedios C, Morimoto S, Zhang L, Ravenscroft G, McNamara E, Nowak KJ, Marston SB, Messer AE.

Cardiovasc Res. 2013 Jul 1;99(1):65-73. doi: 10.1093/cvr/cvt071. Epub 2013 Mar 27.

4.

Cardiac troponin T mutation R141W found in dilated cardiomyopathy stabilizes the troponin T-tropomyosin interaction and causes a Ca2+ desensitization.

Lu QW, Morimoto S, Harada K, Du CK, Takahashi-Yanaga F, Miwa Y, Sasaguri T, Ohtsuki I.

J Mol Cell Cardiol. 2003 Dec;35(12):1421-7.

PMID:
14654368
5.

Investigation of a truncated cardiac troponin T that causes familial hypertrophic cardiomyopathy: Ca(2+) regulatory properties of reconstituted thin filaments depend on the ratio of mutant to wild-type protein.

Redwood C, Lohmann K, Bing W, Esposito GM, Elliott K, Abdulrazzak H, Knott A, Purcell I, Marston S, Watkins H.

Circ Res. 2000 Jun 9;86(11):1146-52.

6.

Dilated cardiomyopathy mutations in three thin filament regulatory proteins result in a common functional phenotype.

Mirza M, Marston S, Willott R, Ashley C, Mogensen J, McKenna W, Robinson P, Redwood C, Watkins H.

J Biol Chem. 2005 Aug 5;280(31):28498-506. Epub 2005 May 27.

7.

Allosteric effects of cardiac troponin TNT1 mutations on actomyosin binding: a novel pathogenic mechanism for hypertrophic cardiomyopathy.

Moore RK, Abdullah S, Tardiff JC.

Arch Biochem Biophys. 2014 Jun 15;552-553:21-8. doi: 10.1016/j.abb.2014.01.016. Epub 2014 Jan 28.

8.

Rat cardiac troponin T mutation (F72L)-mediated impact on thin filament cooperativity is divergently modulated by α- and β-myosin heavy chain isoforms.

Chandra V, Gollapudi SK, Chandra M.

Am J Physiol Heart Circ Physiol. 2015 Oct;309(8):H1260-70. doi: 10.1152/ajpheart.00519.2015. Epub 2015 Sep 4.

PMID:
26342069
9.

Dilated cardiomyopathy mutant tropomyosin mice develop cardiac dysfunction with significantly decreased fractional shortening and myofilament calcium sensitivity.

Rajan S, Ahmed RP, Jagatheesan G, Petrashevskaya N, Boivin GP, Urboniene D, Arteaga GM, Wolska BM, Solaro RJ, Liggett SB, Wieczorek DF.

Circ Res. 2007 Jul 20;101(2):205-14. Epub 2007 Jun 7. Erratum in: Circ Res. 2007 Sep 14;101(6):e80.

10.

The immediate effect of HCM causing actin mutants E99K and A230V on actin-Tm-myosin interaction in thin-filament reconstituted myocardium.

Bai F, Caster HM, Dawson JF, Kawai M.

J Mol Cell Cardiol. 2015 Feb;79:123-32. doi: 10.1016/j.yjmcc.2014.10.014. Epub 2014 Nov 5.

PMID:
25451174
11.
12.

Perturbed length-dependent activation in human hypertrophic cardiomyopathy with missense sarcomeric gene mutations.

Sequeira V, Wijnker PJ, Nijenkamp LL, Kuster DW, Najafi A, Witjas-Paalberends ER, Regan JA, Boontje N, Ten Cate FJ, Germans T, Carrier L, Sadayappan S, van Slegtenhorst MA, Zaremba R, Foster DB, Murphy AM, Poggesi C, Dos Remedios C, Stienen GJ, Ho CY, Michels M, van der Velden J.

Circ Res. 2013 May 24;112(11):1491-505. doi: 10.1161/CIRCRESAHA.111.300436. Epub 2013 Mar 18. Erratum in: Circ Res. 2013 Sep 27;113(8):e87.

13.

Ca2+ sensitivity of regulated cardiac thin filament sliding does not depend on myosin isoform.

Schoffstall B, Brunet NM, Williams S, Miller VF, Barnes AT, Wang F, Compton LA, McFadden LA, Taylor DW, Seavy M, Dhanarajan R, Chase PB.

J Physiol. 2006 Dec 15;577(Pt 3):935-44. Epub 2006 Sep 28.

14.

Mutations in Troponin that cause HCM, DCM AND RCM: what can we learn about thin filament function?

Willott RH, Gomes AV, Chang AN, Parvatiyar MS, Pinto JR, Potter JD.

J Mol Cell Cardiol. 2010 May;48(5):882-92. doi: 10.1016/j.yjmcc.2009.10.031. Epub 2009 Nov 12. Review.

PMID:
19914256
16.

Using baculovirus/insect cell expressed recombinant actin to study the molecular pathogenesis of HCM caused by actin mutation A331P.

Bai F, Caster HM, Rubenstein PA, Dawson JF, Kawai M.

J Mol Cell Cardiol. 2014 Sep;74:64-75. doi: 10.1016/j.yjmcc.2014.04.014. Epub 2014 Apr 30.

17.

Differential interactions of thin filament proteins in two cardiac troponin T mouse models of hypertrophic and dilated cardiomyopathies.

Lombardi R, Bell A, Senthil V, Sidhu J, Noseda M, Roberts R, Marian AJ.

Cardiovasc Res. 2008 Jul 1;79(1):109-17. doi: 10.1093/cvr/cvn078. Epub 2008 Mar 18.

18.

Micromechanical thermal assays of Ca2+-regulated thin-filament function and modulation by hypertrophic cardiomyopathy mutants of human cardiac troponin.

Brunet NM, Mihajlović G, Aledealat K, Wang F, Xiong P, von Molnár S, Chase PB.

J Biomed Biotechnol. 2012;2012:657523. doi: 10.1155/2012/657523. Epub 2012 Feb 14.

19.

Functional analysis of a unique troponin c mutation, GLY159ASP, that causes familial dilated cardiomyopathy, studied in explanted heart muscle.

Dyer EC, Jacques AM, Hoskins AC, Ward DG, Gallon CE, Messer AE, Kaski JP, Burch M, Kentish JC, Marston SB.

Circ Heart Fail. 2009 Sep;2(5):456-64. doi: 10.1161/CIRCHEARTFAILURE.108.818237. Epub 2009 Jul 6.

20.

Characterization of troponin T dilated cardiomyopathy mutations in the fetal troponin isoform.

Venkatraman G, Gomes AV, Kerrick WG, Potter JD.

J Biol Chem. 2005 May 6;280(18):17584-92. Epub 2004 Dec 28.

Format
Items per page
Sort by

Send to:

Choose Destination

Supplemental Content

Write to the Help Desk