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Items: 1 to 20 of 113

1.

USP3 inhibits type I interferon signaling by deubiquitinating RIG-I-like receptors.

Cui J, Song Y, Li Y, Zhu Q, Tan P, Qin Y, Wang HY, Wang RF.

Cell Res. 2014 Apr;24(4):400-16. doi: 10.1038/cr.2013.170. Epub 2013 Dec 24.

2.

Ubiquitin-specific Protease 15 Negatively Regulates Virus-induced Type I Interferon Signaling via Catalytically-dependent and -independent Mechanisms.

Zhang H, Wang D, Zhong H, Luo R, Shang M, Liu D, Chen H, Fang L, Xiao S.

Sci Rep. 2015 Jun 10;5:11220. doi: 10.1038/srep11220.

3.

Activation of duck RIG-I by TRIM25 is independent of anchored ubiquitin.

Miranzo-Navarro D, Magor KE.

PLoS One. 2014 Jan 23;9(1):e86968. doi: 10.1371/journal.pone.0086968. eCollection 2014.

4.

Reconstitution of the RIG-I pathway reveals a signaling role of unanchored polyubiquitin chains in innate immunity.

Zeng W, Sun L, Jiang X, Chen X, Hou F, Adhikari A, Xu M, Chen ZJ.

Cell. 2010 Apr 16;141(2):315-30. doi: 10.1016/j.cell.2010.03.029.

5.

Ubiquitin-induced oligomerization of the RNA sensors RIG-I and MDA5 activates antiviral innate immune response.

Jiang X, Kinch LN, Brautigam CA, Chen X, Du F, Grishin NV, Chen ZJ.

Immunity. 2012 Jun 29;36(6):959-73. doi: 10.1016/j.immuni.2012.03.022. Epub 2012 Jun 14.

6.

The ubiquitin-specific protease USP15 promotes RIG-I-mediated antiviral signaling by deubiquitylating TRIM25.

Pauli EK, Chan YK, Davis ME, Gableske S, Wang MK, Feister KF, Gack MU.

Sci Signal. 2014 Jan 7;7(307):ra3. doi: 10.1126/scisignal.2004577.

7.

A distinct role of Riplet-mediated K63-Linked polyubiquitination of the RIG-I repressor domain in human antiviral innate immune responses.

Oshiumi H, Miyashita M, Matsumoto M, Seya T.

PLoS Pathog. 2013;9(8):e1003533. doi: 10.1371/journal.ppat.1003533. Epub 2013 Aug 8.

8.

TRIM25 RING-finger E3 ubiquitin ligase is essential for RIG-I-mediated antiviral activity.

Gack MU, Shin YC, Joo CH, Urano T, Liang C, Sun L, Takeuchi O, Akira S, Chen Z, Inoue S, Jung JU.

Nature. 2007 Apr 19;446(7138):916-920.

PMID:
17392790
9.

TRIM4 modulates type I interferon induction and cellular antiviral response by targeting RIG-I for K63-linked ubiquitination.

Yan J, Li Q, Mao AP, Hu MM, Shu HB.

J Mol Cell Biol. 2014 Apr;6(2):154-63. doi: 10.1093/jmcb/mju005.

10.

Negative role of RIG-I serine 8 phosphorylation in the regulation of interferon-beta production.

Nistal-Villán E, Gack MU, Martínez-Delgado G, Maharaj NP, Inn KS, Yang H, Wang R, Aggarwal AK, Jung JU, García-Sastre A.

J Biol Chem. 2010 Jun 25;285(26):20252-61. doi: 10.1074/jbc.M109.089912. Epub 2010 Apr 20.

11.

USP21 negatively regulates antiviral response by acting as a RIG-I deubiquitinase.

Fan Y, Mao R, Yu Y, Liu S, Shi Z, Cheng J, Zhang H, An L, Zhao Y, Xu X, Chen Z, Kogiso M, Zhang D, Zhang H, Zhang P, Jung JU, Li X, Xu G, Yang J.

J Exp Med. 2014 Feb 10;211(2):313-28. doi: 10.1084/jem.20122844. Epub 2014 Feb 3.

12.

USP4 positively regulates RIG-I-mediated antiviral response through deubiquitination and stabilization of RIG-I.

Wang L, Zhao W, Zhang M, Wang P, Zhao K, Zhao X, Yang S, Gao C.

J Virol. 2013 Apr;87(8):4507-15. doi: 10.1128/JVI.00031-13. Epub 2013 Feb 6.

13.

USP3 counteracts RNF168 via deubiquitinating H2A and γH2AX at lysine 13 and 15.

Sharma N, Zhu Q, Wani G, He J, Wang QE, Wani AA.

Cell Cycle. 2014;13(1):106-14. doi: 10.4161/cc.26814. Epub 2013 Oct 24.

14.

Downregulation of microRNA miR-526a by enterovirus inhibits RIG-I-dependent innate immune response.

Xu C, He X, Zheng Z, Zhang Z, Wei C, Guan K, Hou L, Zhang B, Zhu L, Cao Y, Zhang Y, Cao Y, Ma S, Wang P, Zhang P, Xu Q, Ling Y, Yang X, Zhong H.

J Virol. 2014 Oct;88(19):11356-68. doi: 10.1128/JVI.01400-14. Epub 2014 Jul 23.

15.

Negative regulation of RIG-I-mediated antiviral signaling by TRK-fused gene (TFG) protein.

Lee NR, Shin HB, Kim HI, Choi MS, Inn KS.

Biochem Biophys Res Commun. 2013 Jul 19;437(1):168-72. doi: 10.1016/j.bbrc.2013.06.061. Epub 2013 Jun 26.

PMID:
23810392
16.

MAVS ubiquitination by the E3 ligase TRIM25 and degradation by the proteasome is involved in type I interferon production after activation of the antiviral RIG-I-like receptors.

Castanier C, Zemirli N, Portier A, Garcin D, Bidère N, Vazquez A, Arnoult D.

BMC Biol. 2012 May 24;10:44. doi: 10.1186/1741-7007-10-44.

17.

Ubiquitin-mediated modulation of the cytoplasmic viral RNA sensor RIG-I.

Oshiumi H, Matsumoto M, Seya T.

J Biochem. 2012 Jan;151(1):5-11. doi: 10.1093/jb/mvr111. Epub 2011 Sep 2. Review.

PMID:
21890623
18.

Conventional protein kinase C-α (PKC-α) and PKC-β negatively regulate RIG-I antiviral signal transduction.

Maharaj NP, Wies E, Stoll A, Gack MU.

J Virol. 2012 Feb;86(3):1358-71. doi: 10.1128/JVI.06543-11. Epub 2011 Nov 23.

19.

Structural and biochemical studies of RIG-I antiviral signaling.

Feng M, Ding Z, Xu L, Kong L, Wang W, Jiao S, Shi Z, Greene MI, Cong Y, Zhou Z.

Protein Cell. 2013 Feb;4(2):142-54. doi: 10.1007/s13238-012-2088-4. Epub 2012 Dec 20.

20.

Riplet/RNF135, a RING finger protein, ubiquitinates RIG-I to promote interferon-beta induction during the early phase of viral infection.

Oshiumi H, Matsumoto M, Hatakeyama S, Seya T.

J Biol Chem. 2009 Jan 9;284(2):807-17. doi: 10.1074/jbc.M804259200. Epub 2008 Nov 18.

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