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Genetic modification and screening in rat using haploid embryonic stem cells.

Li W, Li X, Li T, Jiang MG, Wan H, Luo GZ, Feng C, Cui X, Teng F, Yuan Y, Zhou Q, Gu Q, Shuai L, Sha J, Xiao Y, Wang L, Liu Z, Wang XJ, Zhao XY, Zhou Q.

Cell Stem Cell. 2014 Mar 6;14(3):404-14. doi: 10.1016/j.stem.2013.11.016. Epub 2013 Dec 19.


Haploid embryonic stem cells serve as a new tool for mammalian genetic study.

Shuai L, Zhou Q.

Stem Cell Res Ther. 2014 Feb 6;5(1):20. doi: 10.1186/scrt409. Review.


Androgenetic haploid embryonic stem cells produce live transgenic mice.

Li W, Shuai L, Wan H, Dong M, Wang M, Sang L, Feng C, Luo GZ, Li T, Li X, Wang L, Zheng QY, Sheng C, Wu HJ, Liu Z, Liu L, Wang L, Wang XJ, Zhao XY, Zhou Q.

Nature. 2012 Oct 18;490(7420):407-11. doi: 10.1038/nature11435. Epub 2012 Sep 30.


Derivation of a Homozygous Human Androgenetic Embryonic Stem Cell Line.

Ding C, Huang S, Qi Q, Fu R, Zhu W, Cai B, Hong P, Liu Z, Gu T, Zeng Y, Wang J, Xu Y, Zhao X, Zhou Q, Zhou C.

Stem Cells Dev. 2015 Oct 1;24(19):2307-16. doi: 10.1089/scd.2015.0031. Epub 2015 Aug 24.


CRISPR/Cas9-mediated reporter knock-in in mouse haploid embryonic stem cells.

Kimura Y, Oda M, Nakatani T, Sekita Y, Monfort A, Wutz A, Mochizuki H, Nakano T.

Sci Rep. 2015 Jun 3;5:10710. doi: 10.1038/srep10710.


Derivation of haploid embryonic stem cells from mouse embryos.

Leeb M, Wutz A.

Nature. 2011 Sep 7;479(7371):131-4. doi: 10.1038/nature10448.


CRISPR-Cas9-Mediated Genetic Screening in Mice with Haploid Embryonic Stem Cells Carrying a Guide RNA Library.

Zhong C, Yin Q, Xie Z, Bai M, Dong R, Tang W, Xing YH, Zhang H, Yang S, Chen LL, Bartolomei MS, Ferguson-Smith A, Li D, Yang L, Wu Y, Li J.

Cell Stem Cell. 2015 Aug 6;17(2):221-32. doi: 10.1016/j.stem.2015.06.005. Epub 2015 Jul 9. Erratum in: Cell Stem Cell. 2015 Aug 6;17(2):247.


When half is better than the whole: advances in haploid embryonic stem cell technology.

Kokubu C, Takeda J.

Cell Stem Cell. 2014 Mar 6;14(3):265-7. doi: 10.1016/j.stem.2014.02.001.


Haploid mouse embryonic stem cells: rapid genetic screening and germline transmission.

Wutz A.

Annu Rev Cell Dev Biol. 2014;30:705-22. doi: 10.1146/annurev-cellbio-100913-012920. Review.


Genetic Modification in Human Pluripotent Stem Cells by Homologous Recombination and CRISPR/Cas9 System.

Xue H, Wu J, Li S, Rao MS, Liu Y.

Methods Mol Biol. 2016;1307:173-90. doi: 10.1007/7651_2014_73.


Forward and reverse genetics through derivation of haploid mouse embryonic stem cells.

Elling U, Taubenschmid J, Wirnsberger G, O'Malley R, Demers SP, Vanhaelen Q, Shukalyuk AI, Schmauss G, Schramek D, Schnuetgen F, von Melchner H, Ecker JR, Stanford WL, Zuber J, Stark A, Penninger JM.

Cell Stem Cell. 2011 Dec 2;9(6):563-74. doi: 10.1016/j.stem.2011.10.012.


Powering mammalian genetic screens with mouse haploid embryonic stem cells.

Zhang S, Teng Y.

Mutat Res. 2013 Jan-Feb;741-742:44-50. doi: 10.1016/j.mrfmmm.2013.01.002. Epub 2013 Jan 28. Review.


Efficient gene-targeting in rat embryonic stem cells by CRISPR/Cas and generation of human kynurenine aminotransferase II (KAT II) knock-in rat.

Yamamoto S, Ooshima Y, Nakata M, Yano T, Nishimura N, Nishigaki R, Satomi Y, Matsumoto H, Matsumoto Y, Takeyama M.

Transgenic Res. 2015 Dec;24(6):991-1001. doi: 10.1007/s11248-015-9909-1. Epub 2015 Oct 10.


PSCDGs of mouse multipotent adult germline stem cells can enter and progress through meiosis to form haploid male germ cells in vitro.

Nolte J, Michelmann HW, Wolf M, Wulf G, Nayernia K, Meinhardt A, Zechner U, Engel W.

Differentiation. 2010 Nov-Dec;80(4-5):184-94. doi: 10.1016/j.diff.2010.08.001. Epub 2010 Sep 1.


Genome Editing Using Mammalian Haploid Cells.

Horii T, Hatada I.

Int J Mol Sci. 2015 Oct 1;16(10):23604-14. doi: 10.3390/ijms161023604. Review.


Durable pluripotency and haploidy in epiblast stem cells derived from haploid embryonic stem cells in vitro.

Shuai L, Wang Y, Dong M, Wang X, Sang L, Wang M, Wan H, Luo G, Gu T, Yuan Y, Feng C, Teng F, Li W, Liu X, Li T, Wang L, Wang XJ, Zhao XY, Zhou Q.

J Mol Cell Biol. 2015 Aug;7(4):326-37. doi: 10.1093/jmcb/mjv044. Epub 2015 Jul 13.


Generation of genetically modified mice by oocyte injection of androgenetic haploid embryonic stem cells.

Yang H, Shi L, Wang BA, Liang D, Zhong C, Liu W, Nie Y, Liu J, Zhao J, Gao X, Li D, Xu GL, Li J.

Cell. 2012 Apr 27;149(3):605-17. doi: 10.1016/j.cell.2012.04.002.


Haploid embryonic stem cells: an ideal tool for mammalian genetic analyses.

Shi L, Yang H, Li J.

Protein Cell. 2012 Nov;3(11):806-10. doi: 10.1007/s13238-012-2096-4. Epub 2012 Sep 28. Review.


Germline potential of parthenogenetic haploid mouse embryonic stem cells.

Leeb M, Walker R, Mansfield B, Nichols J, Smith A, Wutz A.

Development. 2012 Sep;139(18):3301-5. doi: 10.1242/dev.083675.


Generation of medaka fish haploid embryonic stem cells.

Yi M, Hong N, Hong Y.

Science. 2009 Oct 16;326(5951):430-3. doi: 10.1126/science.1175151.

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