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Ceramide mediates Ox-LDL-induced human vascular smooth muscle cell calcification via p38 mitogen-activated protein kinase signaling.

Liao L, Zhou Q, Song Y, Wu W, Yu H, Wang S, Chen Y, Ye M, Lu L.

PLoS One. 2013 Dec 16;8(12):e82379. doi: 10.1371/journal.pone.0082379. eCollection 2013.


The role of vascular peroxidase 1 in ox-LDL-induced vascular smooth muscle cell calcification.

Tang Y, Xu Q, Peng H, Liu Z, Yang T, Yu Z, Cheng G, Li X, Zhang G, Shi R.

Atherosclerosis. 2015 Dec;243(2):357-63. doi: 10.1016/j.atherosclerosis.2015.08.047. Epub 2015 Sep 3.


Role of ceramide in activation of stress-associated MAP kinases by minimally modified LDL in vascular smooth muscle cells.

Loidl A, Claus R, Ingolic E, Deigner HP, Hermetter A.

Biochim Biophys Acta. 2004 Oct 14;1690(2):150-8.


Activation of mitogen-activated protein kinase by oxidized low-density lipoprotein in canine cultured vascular smooth muscle cells.

Yang CM, Chiu CT, Wang CC, Chien CS, Hsiao LD, Lin CC, Tu MT, Pan SL.

Cell Signal. 2000 Apr;12(4):205-14.


Mitogenic effect of oxidized low-density lipoprotein on vascular smooth muscle cells mediated by activation of Ras/Raf/MEK/MAPK pathway.

Yang CM, Chien CS, Hsiao LD, Pan SL, Wang CC, Chiu CT, Lin CC.

Br J Pharmacol. 2001 Apr;132(7):1531-41.


Decorin GAG synthesis and TGF-β signaling mediate Ox-LDL-induced mineralization of human vascular smooth muscle cells.

Yan J, Stringer SE, Hamilton A, Charlton-Menys V, Götting C, Müller B, Aeschlimann D, Alexander MY.

Arterioscler Thromb Vasc Biol. 2011 Mar;31(3):608-15. doi: 10.1161/ATVBAHA.110.220749. Epub 2011 Jan 4.


Overexpression of c1q/tumor necrosis factor-related protein-3 promotes phosphate-induced vascular smooth muscle cell calcification both in vivo and in vitro.

Zhou Y, Wang JY, Feng H, Wang C, Li L, Wu D, Lei H, Li H, Wu LL.

Arterioscler Thromb Vasc Biol. 2014 May;34(5):1002-10. doi: 10.1161/ATVBAHA.114.303301. Epub 2014 Feb 27.


Sphingolipids in atherosclerosis and vascular biology.

Chatterjee S.

Arterioscler Thromb Vasc Biol. 1998 Oct;18(10):1523-33. Review.


Peptidoglycan induces cyclooxygenase-2 expression in macrophages by activating the neutral sphingomyelinase-ceramide pathway.

Chen BC, Chang HM, Hsu MJ, Shih CM, Chiu YH, Chiu WT, Lin CH.

J Biol Chem. 2009 Jul 31;284(31):20562-73. doi: 10.1074/jbc.M109.028084. Epub 2009 Jun 15.


Ceramide inhibits Kv currents and contributes to TP-receptor-induced vasoconstriction in rat and human pulmonary arteries.

Moral-Sanz J, Gonzalez T, Menendez C, David M, Moreno L, Macias A, Cortijo J, Valenzuela C, Perez-Vizcaino F, Cogolludo A.

Am J Physiol Cell Physiol. 2011 Jul;301(1):C186-94. doi: 10.1152/ajpcell.00243.2010. Epub 2011 Apr 13.


Curcumin inhibits ox-LDL-induced MCP-1 expression by suppressing the p38MAPK and NF-κB pathways in rat vascular smooth muscle cells.

Zhong Y, Liu T, Guo Z.

Inflamm Res. 2012 Jan;61(1):61-7. doi: 10.1007/s00011-011-0389-3. Epub 2011 Oct 18.


[Over-expression of the cellular repressor of E1A-stimulated genes inhibits the apoptosis of human vascular smooth muscle cells in vitro.].

Han YL, Xu HM, Deng J, Hu Y, Kang J, Liu HW, Yan CH.

Sheng Li Xue Bao. 2006 Aug 25;58(4):324-30. Chinese.


Role for matrix metalloproteinase-2 in oxidized low-density lipoprotein-induced activation of the sphingomyelin/ceramide pathway and smooth muscle cell proliferation.

Augé N, Maupas-Schwalm F, Elbaz M, Thiers JC, Waysbort A, Itohara S, Krell HW, Salvayre R, Nègre-Salvayre A.

Circulation. 2004 Aug 3;110(5):571-8. Epub 2004 Jul 26.


Acrolein activates mitogen-activated protein kinase signal transduction pathways in rat vascular smooth muscle cells.

Ranganna K, Yousefipour Z, Nasif R, Yatsu FM, Milton SG, Hayes BE.

Mol Cell Biochem. 2002 Nov;240(1-2):83-98.


cAMP-response element-binding protein mediates tumor necrosis factor-alpha-induced vascular smooth muscle cell migration.

Ono H, Ichiki T, Fukuyama K, Iino N, Masuda S, Egashira K, Takeshita A.

Arterioscler Thromb Vasc Biol. 2004 Sep;24(9):1634-9. Epub 2004 Jul 8.


Apolipoprotein C-I induces apoptosis in human aortic smooth muscle cells via recruiting neutral sphingomyelinase.

Kolmakova A, Kwiterovich P, Virgil D, Alaupovic P, Knight-Gibson C, Martin SF, Chatterjee S.

Arterioscler Thromb Vasc Biol. 2004 Feb;24(2):264-9. Epub 2003 Dec 11.


Advanced glycation end products induce calcification of vascular smooth muscle cells through RAGE/p38 MAPK.

Tanikawa T, Okada Y, Tanikawa R, Tanaka Y.

J Vasc Res. 2009;46(6):572-80. doi: 10.1159/000226225. Epub 2009 Jun 30.

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