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Results: 1 to 20 of 103

1.

Neonatal Fc receptor promotes immune complex-mediated glomerular disease.

Olaru F, Luo W, Suleiman H, St John PL, Ge L, Mezo AR, Shaw AS, Abrahamson DR, Miner JH, Borza DB.

J Am Soc Nephrol. 2014 May;25(5):918-25. doi: 10.1681/ASN.2013050498. Epub 2013 Dec 19.

PMID:
24357670
[PubMed - indexed for MEDLINE]
2.

FcRn-mediated intestinal absorption of IgG anti-IgE/IgE immune complexes in mice.

Paveglio S, Puddington L, Rafti E, Matson AP.

Clin Exp Allergy. 2012 Dec;42(12):1791-800. doi: 10.1111/j.1365-2222.2012.04043.x.

PMID:
23181795
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Proteolysis breaks tolerance toward intact α345(IV) collagen, eliciting novel anti-glomerular basement membrane autoantibodies specific for α345NC1 hexamers.

Olaru F, Wang XP, Luo W, Ge L, Miner JH, Kleinau S, Geiger XJ, Wasiluk A, Heidet L, Kitching AR, Borza DB.

J Immunol. 2013 Feb 15;190(4):1424-32. doi: 10.4049/jimmunol.1202204. Epub 2013 Jan 9.

PMID:
23303673
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Murine membranous nephropathy: immunization with α3(IV) collagen fragment induces subepithelial immune complexes and FcγR-independent nephrotic syndrome.

Zhang JJ, Malekpour M, Luo W, Ge L, Olaru F, Wang XP, Bah M, Sado Y, Heidet L, Kleinau S, Fogo AB, Borza DB.

J Immunol. 2012 Apr 1;188(7):3268-77. doi: 10.4049/jimmunol.1103368. Epub 2012 Feb 27.

PMID:
22371398
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Nephrotic syndrome and subepithelial deposits in a mouse model of immune-mediated anti-podocyte glomerulonephritis.

Meyer-Schwesinger C, Dehde S, Klug P, Becker JU, Mathey S, Arefi K, Balabanov S, Venz S, Endlich KH, Pekna M, Gessner JE, Thaiss F, Meyer TN.

J Immunol. 2011 Sep 15;187(6):3218-29. doi: 10.4049/jimmunol.1003451. Epub 2011 Aug 15.

PMID:
21844386
[PubMed - indexed for MEDLINE]
Free Article
6.

An FcRn-dependent role for anti-flagellin immunoglobulin G in pathogenesis of colitis in mice.

Kobayashi K, Qiao SW, Yoshida M, Baker K, Lencer WI, Blumberg RS.

Gastroenterology. 2009 Nov;137(5):1746-56.e1. doi: 10.1053/j.gastro.2009.07.059. Epub 2009 Aug 4.

PMID:
19664634
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Neonatal Fc receptor deficiency protects from tissue injury in experimental epidermolysis bullosa acquisita.

Sesarman A, Sitaru AG, Olaru F, Zillikens D, Sitaru C.

J Mol Med (Berl). 2008 Aug;86(8):951-9. doi: 10.1007/s00109-008-0366-7. Epub 2008 Jun 10.

PMID:
18542899
[PubMed - indexed for MEDLINE]
8.

Humanized FcRn mouse models for evaluating pharmacokinetics of human IgG antibodies.

Proetzel G, Roopenian DC.

Methods. 2014 Jan 1;65(1):148-53. doi: 10.1016/j.ymeth.2013.07.005. Epub 2013 Jul 16.

PMID:
23867339
[PubMed - indexed for MEDLINE]
9.

Localization of the membrane attack complex (MAC) in experimental immune complex glomerulonephritis.

Koffler D, Biesecker G, Noble B, Andres GA, Martinez-Hernandez A.

J Exp Med. 1983 Jun 1;157(6):1885-905.

PMID:
6343549
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Physiologically-based pharmacokinetic (PBPK) model to predict IgG tissue kinetics in wild-type and FcRn-knockout mice.

Garg A, Balthasar JP.

J Pharmacokinet Pharmacodyn. 2007 Oct;34(5):687-709. Epub 2007 Jul 18.

PMID:
17636457
[PubMed - indexed for MEDLINE]
11.

Abolition of anti-glomerular basement membrane antibody-mediated glomerulonephritis in FcRgamma-deficient mice.

Wakayama H, Hasegawa Y, Kawabe T, Hara T, Matsuo S, Mizuno M, Takai T, Kikutani H, Shimokata K.

Eur J Immunol. 2000 Apr;30(4):1182-90.

PMID:
10760808
[PubMed - indexed for MEDLINE]
12.

Renal FcRn reclaims albumin but facilitates elimination of IgG.

Sarav M, Wang Y, Hack BK, Chang A, Jensen M, Bao L, Quigg RJ.

J Am Soc Nephrol. 2009 Sep;20(9):1941-52. doi: 10.1681/ASN.2008090976. Epub 2009 Aug 6.

PMID:
19661163
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Importance of neonatal FcR in regulating the serum half-life of therapeutic proteins containing the Fc domain of human IgG1: a comparative study of the affinity of monoclonal antibodies and Fc-fusion proteins to human neonatal FcR.

Suzuki T, Ishii-Watabe A, Tada M, Kobayashi T, Kanayasu-Toyoda T, Kawanishi T, Yamaguchi T.

J Immunol. 2010 Feb 15;184(4):1968-76. doi: 10.4049/jimmunol.0903296. Epub 2010 Jan 18.

PMID:
20083659
[PubMed - indexed for MEDLINE]
Free Article
14.

Complete FcRn dependence for intravenous Ig therapy in autoimmune skin blistering diseases.

Li N, Zhao M, Hilario-Vargas J, Prisayanh P, Warren S, Diaz LA, Roopenian DC, Liu Z.

J Clin Invest. 2005 Dec;115(12):3440-50. Epub 2005 Nov 10.

PMID:
16284651
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Neonatal Fc receptor for IgG (FcRn) regulates cross-presentation of IgG immune complexes by CD8-CD11b+ dendritic cells.

Baker K, Qiao SW, Kuo TT, Aveson VG, Platzer B, Andersen JT, Sandlie I, Chen Z, de Haar C, Lencer WI, Fiebiger E, Blumberg RS.

Proc Natl Acad Sci U S A. 2011 Jun 14;108(24):9927-32. doi: 10.1073/pnas.1019037108. Epub 2011 May 31.

PMID:
21628593
[PubMed - indexed for MEDLINE]
Free PMC Article
16.
17.

FcRn: an IgG receptor on phagocytes with a novel role in phagocytosis.

Vidarsson G, Stemerding AM, Stapleton NM, Spliethoff SE, Janssen H, Rebers FE, de Haas M, van de Winkel JG.

Blood. 2006 Nov 15;108(10):3573-9. Epub 2006 Jul 18.

PMID:
16849638
[PubMed - indexed for MEDLINE]
Free Article
18.

Animal model of fetal and neonatal immune thrombocytopenia: role of neonatal Fc receptor in the pathogenesis and therapy.

Chen P, Li C, Lang S, Zhu G, Reheman A, Spring CM, Freedman J, Ni H.

Blood. 2010 Nov 4;116(18):3660-8. doi: 10.1182/blood-2010-05-284919. Epub 2010 Jul 20.

PMID:
20647570
[PubMed - indexed for MEDLINE]
Free Article
19.

The neonatal Fc receptor (FcRn) is not required for IVIg or anti-CD44 monoclonal antibody-mediated amelioration of murine immune thrombocytopenia.

Crow AR, Suppa SJ, Chen X, Mott PJ, Lazarus AH.

Blood. 2011 Dec 8;118(24):6403-6. doi: 10.1182/blood-2011-08-374223. Epub 2011 Oct 14.

PMID:
22001393
[PubMed - indexed for MEDLINE]
Free Article
20.

Qualification of a homogeneous cell-based neonatal Fc receptor (FcRn) binding assay and its application to studies on Fc functionality of IgG-based therapeutics.

Mathur A, Arora T, Liu L, Crouse-Zeineddini J, Mukku V.

J Immunol Methods. 2013 Apr 30;390(1-2):81-91. doi: 10.1016/j.jim.2013.01.011. Epub 2013 Feb 4.

PMID:
23384837
[PubMed - indexed for MEDLINE]

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