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Items: 1 to 20 of 115

1.

Cbl-b enhances sensitivity to 5-fluorouracil via EGFR- and mitochondria-mediated pathways in gastric cancer cells.

Feng D, Ma Y, Liu J, Xu L, Zhang Y, Qu J, Liu Y, Qu X.

Int J Mol Sci. 2013 Dec 16;14(12):24399-411. doi: 10.3390/ijms141224399.

2.

Ubiquitin ligase Cbl-b represses IGF-I-induced epithelial mesenchymal transition via ZEB2 and microRNA-200c regulation in gastric cancer cells.

Li H, Xu L, Li C, Zhao L, Ma Y, Zheng H, Li Z, Zhang Y, Wang R, Liu Y, Qu X.

Mol Cancer. 2014 Jun 2;13:136. doi: 10.1186/1476-4598-13-136.

3.

PI3K/Akt is involved in bufalin-induced apoptosis in gastric cancer cells.

Li D, Qu X, Hou K, Zhang Y, Dong Q, Teng Y, Zhang J, Liu Y.

Anticancer Drugs. 2009 Jan;20(1):59-64. doi: 10.1097/CAD.0b013e3283160fd6.

PMID:
19343001
4.

Cbl-b promotes chemotherapy-induced apoptosis in rat basophilic leukemia cells by suppressing PI3K/Akt activation and enhancing MEK/ERK activation.

Qu X, Li Y, Liu J, Xu L, Zhang Y, Hu X, Hou K, Liu Y.

Mol Cell Biochem. 2010 Jul;340(1-2):107-14. doi: 10.1007/s11010-010-0407-8. Epub 2010 Feb 24.

PMID:
20177738
5.

Ubiquitin ligase Cbl-b sensitizes leukemia and gastric cancer cells to anthracyclines by activating the mitochondrial pathway and modulating Akt and ERK survival signals.

Qu X, Zhang Y, Li Y, Hu X, Xu Y, Xu L, Hou K, Sada K, Liu Y.

FEBS Lett. 2009 Jul 7;583(13):2255-62. doi: 10.1016/j.febslet.2009.05.054. Epub 2009 Jun 7.

6.

TRAIL-activated EGFR by Cbl-b-regulated EGFR redistribution in lipid rafts antagonises TRAIL-induced apoptosis in gastric cancer cells.

Xu L, Zhang Y, Liu J, Qu J, Hu X, Zhang F, Zheng H, Qu X, Liu Y.

Eur J Cancer. 2012 Nov;48(17):3288-99. doi: 10.1016/j.ejca.2012.03.005. Epub 2012 Mar 27.

PMID:
22456178
7.

TRAIL/MEKK4/p38/HSP27/Akt survival network is biphasically modulated by the Src/CIN85/c-Cbl complex.

Kim J, Kang D, Sun BK, Kim JH, Song JJ.

Cell Signal. 2013 Jan;25(1):372-9. doi: 10.1016/j.cellsig.2012.10.010. Epub 2012 Oct 23.

PMID:
23085457
8.

Ubiquitin ligase Cbl-b is involved in icotinib (BPI-2009H)-induced apoptosis and G1 phase arrest of EGFR mutation-positive non-small-cell lung cancer.

Mu X, Zhang Y, Qu X, Hou K, Kang J, Hu X, Liu Y.

Biomed Res Int. 2013;2013:726375. doi: 10.1155/2013/726375. Epub 2013 Mar 19.

9.

Celecoxib sensitizes gastric cancer to rapamycin via inhibition of the Cbl-b-regulated PI3K/Akt pathway.

Cao Y, Qu J, Li C, Yang D, Hou K, Zheng H, Liu Y, Qu X.

Tumour Biol. 2015 Jul;36(7):5607-15. doi: 10.1007/s13277-015-3232-6. Epub 2015 Feb 21.

PMID:
25701378
10.

Cannabinoid receptor agonist as an alternative drug in 5-fluorouracil-resistant gastric cancer cells.

Xian XS, Park H, Choi MG, Park JM.

Anticancer Res. 2013 Jun;33(6):2541-7.

PMID:
23749906
11.
12.

Neuronal Cbl controls biosynthesis of insulin-like peptides in Drosophila melanogaster.

Yu Y, Sun Y, He S, Yan C, Rui L, Li W, Liu Y.

Mol Cell Biol. 2012 Sep;32(18):3610-23. doi: 10.1128/MCB.00592-12. Epub 2012 Jul 9.

13.

CIN85 is required for Cbl-mediated regulation of antigen receptor signaling in human B cells.

Niiro H, Jabbarzadeh-Tabrizi S, Kikushige Y, Shima T, Noda K, Ota S, Tsuzuki H, Inoue Y, Arinobu Y, Iwasaki H, Shimoda S, Baba E, Tsukamoto H, Horiuchi T, Taniyama T, Akashi K.

Blood. 2012 Mar 8;119(10):2263-73. doi: 10.1182/blood-2011-04-351965. Epub 2012 Jan 18.

14.

Cbl-regulated Akt and ERK signals are involved in β-elemene-induced cell apoptosis in lung cancer cells.

Li L, Xu L, Qu X, Zhao M, Yu P, Kang J, Liu Y, Hu X.

Mol Med Rep. 2011 Nov-Dec;4(6):1243-6. doi: 10.3892/mmr.2011.548. Epub 2011 Aug 11.

PMID:
21837364
15.

Secreted protein acidic and rich in cysteine antagonizes bufalin-induced apoptosis in gastric cancer cells.

Li A, Qu X, Li Z, Qu J, Song N, Ma Y, Liu Y.

Mol Med Rep. 2015 Aug;12(2):2926-32. doi: 10.3892/mmr.2015.3676. Epub 2015 Apr 24.

PMID:
25936899
16.

Gefitinib, a selective EGFR tyrosine kinase inhibitor, induces apoptosis through activation of Bax in human gallbladder adenocarcinoma cells.

Ariyama H, Qin B, Baba E, Tanaka R, Mitsugi K, Harada M, Nakano S.

J Cell Biochem. 2006 Mar 1;97(4):724-34.

PMID:
16229013
17.

Ubiquitin ligase c-Cbl is involved in tamoxifen-induced apoptosis of MCF-7 cells by downregulating the survival signals.

Yan SC, Liu YP, Zhang LY, Qu JL, Xu L, Liu J, Zhang Y, Hou KZ, Teng YE, Qu XJ.

Acta Oncol. 2011 Jun;50(5):693-9. doi: 10.3109/0284186X.2010.543144. Epub 2010 Dec 22.

PMID:
21175263
18.

Knockdown of the Bcl-2 gene increases sensitivity to EGFR tyrosine kinase inhibitors in the H1975 lung cancer cell line harboring T790M mutation.

Zou M, Xia S, Zhuang L, Han N, Chu Q, Chao T, Peng P, Chen Y, Gui Q, Yu S.

Int J Oncol. 2013 Jun;42(6):2094-102. doi: 10.3892/ijo.2013.1895. Epub 2013 Apr 12.

PMID:
23588221
19.

Cbl-b-dependent degradation of FLIP(L) is involved in ATO-induced autophagy in leukemic K562 and gastric cancer cells.

Zhang G, Liu J, Zhang Y, Qu J, Xu L, Zheng H, Liu Y, Qu X.

FEBS Lett. 2012 Sep 21;586(19):3104-10. doi: 10.1016/j.febslet.2012.07.067. Epub 2012 Aug 1.

20.

Apoptosis induced by depsipeptide FK228 coincides with inhibition of survival signaling in lung cancer cells.

Yu XD, Wang SY, Chen GA, Hou CM, Zhao M, Hong JA, Nguyen DM, Schrump DS.

Cancer J. 2007 Mar-Apr;13(2):105-13.

PMID:
17476138
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