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Items: 1 to 20 of 108

1.

Fibroblast growth factor receptor 1 signaling in adult cardiomyocytes increases contractility and results in a hypertrophic cardiomyopathy.

Cilvik SN, Wang JI, Lavine KJ, Uchida K, Castro A, Gierasch CM, Weinheimer CJ, House SL, Kovacs A, Nichols CG, Ornitz DM.

PLoS One. 2013 Dec 11;8(12):e82979. doi: 10.1371/journal.pone.0082979. eCollection 2013.

2.

Dapper-1 induces myocardial remodeling through activation of canonical Wnt signaling in cardiomyocytes.

Hagenmueller M, Riffel JH, Bernhold E, Fan J, Zhang M, Ochs M, Steinbeisser H, Katus HA, Hardt SE.

Hypertension. 2013 Jun;61(6):1177-83. doi: 10.1161/HYPERTENSIONAHA.111.00391. Epub 2013 Mar 18.

3.

MAPK-activated protein kinase-2 in cardiac hypertrophy and cyclooxygenase-2 regulation in heart.

Streicher JM, Ren S, Herschman H, Wang Y.

Circ Res. 2010 Apr 30;106(8):1434-43. doi: 10.1161/CIRCRESAHA.109.213199. Epub 2010 Mar 25.

4.

Wnt signaling is critical for maladaptive cardiac hypertrophy and accelerates myocardial remodeling.

Malekar P, Hagenmueller M, Anyanwu A, Buss S, Streit MR, Weiss CS, Wolf D, Riffel J, Bauer A, Katus HA, Hardt SE.

Hypertension. 2010 Apr;55(4):939-45. doi: 10.1161/HYPERTENSIONAHA.109.141127. Epub 2010 Feb 22.

5.

Endothelin-1 induces myofibrillar disarray and contractile vector variability in hypertrophic cardiomyopathy-induced pluripotent stem cell-derived cardiomyocytes.

Tanaka A, Yuasa S, Mearini G, Egashira T, Seki T, Kodaira M, Kusumoto D, Kuroda Y, Okata S, Suzuki T, Inohara T, Arimura T, Makino S, Kimura K, Kimura A, Furukawa T, Carrier L, Node K, Fukuda K.

J Am Heart Assoc. 2014 Nov 11;3(6):e001263. doi: 10.1161/JAHA.114.001263.

6.

Cyclic nucleotide phosphodiesterase 3A1 protects the heart against ischemia-reperfusion injury.

Oikawa M, Wu M, Lim S, Knight WE, Miller CL, Cai Y, Lu Y, Blaxall BC, Takeishi Y, Abe J, Yan C.

J Mol Cell Cardiol. 2013 Nov;64:11-9. doi: 10.1016/j.yjmcc.2013.08.003. Epub 2013 Aug 27.

7.

Angiotensin II type-1 receptor activation in the adult heart causes blood pressure-independent hypertrophy and cardiac dysfunction.

Ainscough JF, Drinkhill MJ, Sedo A, Turner NA, Brooke DA, Balmforth AJ, Ball SG.

Cardiovasc Res. 2009 Feb 15;81(3):592-600. doi: 10.1093/cvr/cvn230. Epub 2008 Aug 14.

8.

Inhibition of AP-1 signaling by JDP2 overexpression protects cardiomyocytes against hypertrophy and apoptosis induction.

Hill C, Würfel A, Heger J, Meyering B, Schlüter KD, Weber M, Ferdinandy P, Aronheim A, Schulz R, Euler G.

Cardiovasc Res. 2013 Jul 1;99(1):121-8. doi: 10.1093/cvr/cvt094. Epub 2013 Apr 23.

9.

Nampt secreted from cardiomyocytes promotes development of cardiac hypertrophy and adverse ventricular remodeling.

Pillai VB, Sundaresan NR, Kim G, Samant S, Moreno-Vinasco L, Garcia JG, Gupta MP.

Am J Physiol Heart Circ Physiol. 2013 Feb 1;304(3):H415-26. doi: 10.1152/ajpheart.00468.2012. Epub 2012 Nov 30.

10.

Overexpression of the serotonin 5-HT2B receptor in heart leads to abnormal mitochondrial function and cardiac hypertrophy.

Nebigil CG, Jaffré F, Messaddeq N, Hickel P, Monassier L, Launay JM, Maroteaux L.

Circulation. 2003 Jul 1;107(25):3223-9. Epub 2003 Jun 16.

11.

Reversibility of adverse, calcineurin-dependent cardiac remodeling.

Berry JM, Le V, Rotter D, Battiprolu PK, Grinsfelder B, Tannous P, Burchfield JS, Czubryt M, Backs J, Olson EN, Rothermel BA, Hill JA.

Circ Res. 2011 Aug 5;109(4):407-17. doi: 10.1161/CIRCRESAHA.110.228452. Epub 2011 Jun 23.

12.

MicroRNA-22 regulates cardiac hypertrophy and remodeling in response to stress.

Huang ZP, Chen J, Seok HY, Zhang Z, Kataoka M, Hu X, Wang DZ.

Circ Res. 2013 Apr 26;112(9):1234-43. doi: 10.1161/CIRCRESAHA.112.300682. Epub 2013 Mar 22.

13.

Raf-mediated cardiac hypertrophy in adult Drosophila.

Yu L, Daniels J, Glaser AE, Wolf MJ.

Dis Model Mech. 2013 Jul;6(4):964-76. doi: 10.1242/dmm.011361. Epub 2013 Apr 4.

14.

Cardiac-specific Traf2 overexpression enhances cardiac hypertrophy through activating AKT/GSK3β signaling.

Huang Y, Wu D, Zhang X, Jiang M, Hu C, Lin J, Tang J, Wu L.

Gene. 2014 Feb 25;536(2):225-31. doi: 10.1016/j.gene.2013.12.052. Epub 2013 Dec 27.

PMID:
24378234
15.

Ginseng reverses established cardiomyocyte hypertrophy and postmyocardial infarction-induced hypertrophy and heart failure.

Moey M, Gan XT, Huang CX, Rajapurohitam V, Martínez-Abundis E, Lui EM, Karmazyn M.

Circ Heart Fail. 2012 Jul 1;5(4):504-14. doi: 10.1161/CIRCHEARTFAILURE.112.967489. Epub 2012 May 10.

16.

FGF23 is a novel regulator of intracellular calcium and cardiac contractility in addition to cardiac hypertrophy.

Touchberry CD, Green TM, Tchikrizov V, Mannix JE, Mao TF, Carney BW, Girgis M, Vincent RJ, Wetmore LA, Dawn B, Bonewald LF, Stubbs JR, Wacker MJ.

Am J Physiol Endocrinol Metab. 2013 Apr 15;304(8):E863-73. doi: 10.1152/ajpendo.00596.2012. Epub 2013 Feb 26.

17.

Activation of Na+/H+ exchanger 1 is sufficient to generate Ca2+ signals that induce cardiac hypertrophy and heart failure.

Nakamura TY, Iwata Y, Arai Y, Komamura K, Wakabayashi S.

Circ Res. 2008 Oct 10;103(8):891-9. doi: 10.1161/CIRCRESAHA.108.175141. Epub 2008 Sep 5.

18.

Angiotensin II-mediated phenotypic cardiomyocyte remodeling leads to age-dependent cardiac dysfunction and failure.

Domenighetti AA, Wang Q, Egger M, Richards SM, Pedrazzini T, Delbridge LM.

Hypertension. 2005 Aug;46(2):426-32. Epub 2005 Jul 5.

19.

Enhanced expression of β3-adrenoceptors in cardiac myocytes attenuates neurohormone-induced hypertrophic remodeling through nitric oxide synthase.

Belge C, Hammond J, Dubois-Deruy E, Manoury B, Hamelet J, Beauloye C, Markl A, Pouleur AC, Bertrand L, Esfahani H, Jnaoui K, Götz KR, Nikolaev VO, Vanderper A, Herijgers P, Lobysheva I, Iaccarino G, Hilfiker-Kleiner D, Tavernier G, Langin D, Dessy C, Balligand JL.

Circulation. 2014 Jan 28;129(4):451-62. doi: 10.1161/CIRCULATIONAHA.113.004940. Epub 2013 Nov 4.

20.

Transgenic overexpression of platelet-derived growth factor-C in the mouse heart induces cardiac fibrosis, hypertrophy, and dilated cardiomyopathy.

Pontén A, Li X, Thorén P, Aase K, Sjöblom T, Ostman A, Eriksson U.

Am J Pathol. 2003 Aug;163(2):673-82.

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