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Results: 1 to 20 of 100

1.

In silico, in vitro and in vivo analysis of binding affinity between N and C-domains of clostridium perfringens alpha toxin.

Uppalapati SR, Kingston JJ, Qureshi IA, Murali HS, Batra HV.

PLoS One. 2013 Dec 11;8(12):e82024. doi: 10.1371/journal.pone.0082024. eCollection 2013.

PMID:
24349173
[PubMed - in process]
Free PMC Article
2.

Role of Clostridium perfringens phospholipase C in the pathogenesis of gas gangrene.

Flores-Díaz M, Alape-Girón A.

Toxicon. 2003 Dec 15;42(8):979-86. Review.

PMID:
15019495
[PubMed - indexed for MEDLINE]
3.

Role of the C-domain in the biological activities of Clostridium perfringens alpha-toxin.

Nagahama M, Mukai M, Morimitsu S, Ochi S, Sakurai J.

Microbiol Immunol. 2002;46(10):647-55.

PMID:
12477243
[PubMed - indexed for MEDLINE]
4.

Phospholipase C produced by Clostridium botulinum types C and D: comparison of gene, enzymatic, and biological activities with those of Clostridium perfringens alpha-toxin.

Fatmawati NN, Sakaguchi Y, Suzuki T, Oda M, Shimizu K, Yamamoto Y, Sakurai J, Matsushita O, Oguma K.

Acta Med Okayama. 2013;67(1):9-18.

PMID:
23439504
[PubMed - indexed for MEDLINE]
Free Article
5.

Clostridium perfringens alpha-toxin: characterization and mode of action.

Sakurai J, Nagahama M, Oda M.

J Biochem. 2004 Nov;136(5):569-74. Review.

PMID:
15632295
[PubMed - indexed for MEDLINE]
Free Article
7.

Identification of residues critical for toxicity in Clostridium perfringens phospholipase C, the key toxin in gas gangrene.

Alape-Girón A, Flores-Díaz M, Guillouard I, Naylor CE, Titball RW, Rucavado A, Lomonte B, Basak AK, Gutiérrez JM, Cole ST, Thelestam M.

Eur J Biochem. 2000 Aug;267(16):5191-7.

PMID:
10931204
[PubMed - indexed for MEDLINE]
Free Article
8.

Neutralization of hemolytic and mouse lethal activities of C. perfringens alpha-toxin need simultaneous blockade of two epitopes by monoclonal antibodies.

Schoepe H, Wieler LH, Bauerfeind R, Schlapp T, Potschka H, Hehnen HR, Baljer G.

Microb Pathog. 1997 Jul;23(1):1-10.

PMID:
9250775
[PubMed - indexed for MEDLINE]
9.

Effects of Clostridium perfringens phospholipase C in mammalian cells.

Flores-Díaz M, Thelestam M, Clark GC, Titball RW, Alape-Girón A.

Anaerobe. 2004 Apr;10(2):115-23.

PMID:
16701508
[PubMed]
10.

Cross-complementation of Clostridium perfringens PLC and Clostridium septicum alpha-toxin mutants reveals PLC is sufficient to mediate gas gangrene.

Kennedy CL, Lyras D, Cheung JK, Hiscox TJ, Emmins JJ, Rood JI.

Microbes Infect. 2009 Mar;11(3):413-8. doi: 10.1016/j.micinf.2009.01.002. Epub 2009 Jan 20.

PMID:
19284973
[PubMed - indexed for MEDLINE]
11.

A cellular deficiency of gangliosides causes hypersensitivity to Clostridium perfringens phospholipase C.

Flores-Díaz M, Alape-Girón A, Clark G, Catimel B, Hirabayashi Y, Nice E, Gutiérrez JM, Titball R, Thelestam M.

J Biol Chem. 2005 Jul 22;280(29):26680-9. Epub 2005 May 26.

PMID:
15919667
[PubMed - indexed for MEDLINE]
Free Article
12.

A recombinant carboxy-terminal domain of alpha-toxin protects mice against Clostridium perfringens.

Nagahama M, Oda M, Kobayashi K, Ochi S, Takagishi T, Shibutani M, Sakurai J.

Microbiol Immunol. 2013 May;57(5):340-5. doi: 10.1111/1348-0421.12036.

PMID:
23668605
[PubMed - indexed for MEDLINE]
13.

Gene cloning shows the alpha-toxin of Clostridium perfringens to contain both sphingomyelinase and lecithinase activities.

Saint-Joanis B, Garnier T, Cole ST.

Mol Gen Genet. 1989 Nov;219(3):453-60.

PMID:
2560137
[PubMed - indexed for MEDLINE]
14.

Structure of the key toxin in gas gangrene.

Naylor CE, Eaton JT, Howells A, Justin N, Moss DS, Titball RW, Basak AK.

Nat Struct Biol. 1998 Aug;5(8):738-46.

PMID:
9699639
[PubMed - indexed for MEDLINE]
15.

Analysis of protection afforded by a Clostridium perfringens alpha-toxoid against heterologous clostridial phospholipases C.

Neeson BN, Clark GC, Atkins HS, Lingard B, Titball RW.

Microb Pathog. 2007 Oct;43(4):161-5. Epub 2007 May 18.

PMID:
17604945
[PubMed - indexed for MEDLINE]
17.

The carboxy-terminal C2-like domain of the alpha-toxin from Clostridium perfringens mediates calcium-dependent membrane recognition.

Guillouard I, Alzari PM, Saliou B, Cole ST.

Mol Microbiol. 1997 Dec;26(5):867-76.

PMID:
9426125
[PubMed - indexed for MEDLINE]
18.

Vaccines against Clostridium perfringens alpha-toxin.

Nagahama M.

Curr Pharm Biotechnol. 2014 Nov;14(10):913-7.

PMID:
24372250
[PubMed - in process]
19.

Enhanced production of phospholipase C and perfringolysin O (alpha and theta toxins) in a gatifloxacin-resistant strain of Clostridium perfringens.

Rafii F, Park M, Bryant AE, Johnson SJ, Wagner RD.

Antimicrob Agents Chemother. 2008 Mar;52(3):895-900. Epub 2007 Dec 26.

PMID:
18160514
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Characterization of polymorphisms and isoforms of the Clostridium perfringens phospholipase C gene (plc) reveals high genetic diversity.

Siqueira FF, Almeida MO, Barroca TM, Horta CC, Carmo AO, Silva RO, Pires PS, Lobato FC, Kalapothakis E.

Vet Microbiol. 2012 Oct 12;159(3-4):397-405. doi: 10.1016/j.vetmic.2012.04.012. Epub 2012 Apr 17.

PMID:
22560738
[PubMed - indexed for MEDLINE]

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