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Results: 1 to 20 of 122

1.

Skp2 regulates androgen receptor through ubiquitin-mediated degradation independent of Akt/mTOR pathways in prostate cancer.

Li B, Lu W, Yang Q, Yu X, Matusik RJ, Chen Z.

Prostate. 2014 Apr;74(4):421-32. doi: 10.1002/pros.22763. Epub 2013 Dec 17.

PMID:
24347472
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Androgen Receptor Enhances p27 Degradation in Prostate Cancer Cells through Rapid and Selective TORC2 Activation.

Fang Z, Zhang T, Dizeyi N, Chen S, Wang H, Swanson KD, Cai C, Balk SP, Yuan X.

J Biol Chem. 2012 Jan 13;287(3):2090-8. doi: 10.1074/jbc.M111.323303. Epub 2011 Dec 2.

PMID:
22139837
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

PI3K-AKT-mTOR pathway is dominant over androgen receptor signaling in prostate cancer cells.

Kaarbø M, Mikkelsen OL, Malerød L, Qu S, Lobert VH, Akgul G, Halvorsen T, Maelandsmo GM, Saatcioglu F.

Cell Oncol. 2010;32(1-2):11-27. doi: 10.3233/CLO-2009-0487.

PMID:
20203370
[PubMed - indexed for MEDLINE]
4.

GCP-mediated growth inhibition and apoptosis of prostate cancer cells via androgen receptor-dependent and -independent mechanisms.

Tepper CG, Vinall RL, Wee CB, Xue L, Shi XB, Burich R, Mack PC, de Vere White RW.

Prostate. 2007 Apr 1;67(5):521-35.

PMID:
17252539
[PubMed - indexed for MEDLINE]
5.

Resveratrol regulates the PTEN/AKT pathway through androgen receptor-dependent and -independent mechanisms in prostate cancer cell lines.

Wang Y, Romigh T, He X, Orloff MS, Silverman RH, Heston WD, Eng C.

Hum Mol Genet. 2010 Nov 15;19(22):4319-29. doi: 10.1093/hmg/ddq354. Epub 2010 Aug 20.

PMID:
20729295
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Nrdp1-mediated regulation of ErbB3 expression by the androgen receptor in androgen-dependent but not castrate-resistant prostate cancer cells.

Chen L, Siddiqui S, Bose S, Mooso B, Asuncion A, Bedolla RG, Vinall R, Tepper CG, Gandour-Edwards R, Shi X, Lu XH, Siddiqui J, Chinnaiyan AM, Mehra R, Devere White RW, Carraway KL 3rd, Ghosh PM.

Cancer Res. 2010 Jul 15;70(14):5994-6003. doi: 10.1158/0008-5472.CAN-09-4440. Epub 2010 Jun 29.

PMID:
20587519
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Isosilybin B causes androgen receptor degradation in human prostate carcinoma cells via PI3K-Akt-Mdm2-mediated pathway.

Deep G, Oberlies NH, Kroll DJ, Agarwal R.

Oncogene. 2008 Jun 26;27(28):3986-98. doi: 10.1038/onc.2008.45. Epub 2008 Mar 10.

PMID:
18332867
[PubMed - indexed for MEDLINE]
8.

Androgens repress expression of the F-box protein Skp2 via p107 dependent and independent mechanisms in LNCaP prostate cancer cells.

Jiang J, Pan Y, Regan KM, Wu C, Zhang X, Tindall DJ, Huang H.

Prostate. 2012 Feb 1;72(2):225-32. doi: 10.1002/pros.21430. Epub 2011 May 31.

PMID:
21630295
[PubMed - indexed for MEDLINE]
9.

Androgen suppresses proliferation of castration-resistant LNCaP 104-R2 prostate cancer cells through androgen receptor, Skp2, and c-Myc.

Chuu CP, Kokontis JM, Hiipakka RA, Fukuchi J, Lin HP, Lin CY, Huo C, Su LC, Liao S.

Cancer Sci. 2011 Nov;102(11):2022-8. doi: 10.1111/j.1349-7006.2011.02043.x. Epub 2011 Aug 18. Erratum in: Cancer Sci. 2013 Jan;104(1):142. Huo, Chiech [corrected to Huo, Chieh].

PMID:
21781227
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

An AR-Skp2 pathway for proliferation of androgen-dependent prostate-cancer cells.

Wang H, Sun D, Ji P, Mohler J, Zhu L.

J Cell Sci. 2008 Aug 1;121(Pt 15):2578-87. doi: 10.1242/jcs.030742. Epub 2008 Jul 15.

PMID:
18628304
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Brassinin induces apoptosis in PC-3 human prostate cancer cells through the suppression of PI3K/Akt/mTOR/S6K1 signaling cascades.

Kim SM, Park JH, Kim KD, Nam D, Shim BS, Kim SH, Ahn KS, Choi SH, Ahn KS.

Phytother Res. 2014 Mar;28(3):423-31. doi: 10.1002/ptr.5010. Epub 2013 May 20.

PMID:
23686889
[PubMed - indexed for MEDLINE]
12.

Nuclear export signal of androgen receptor (NESAR) regulation of androgen receptor level in human prostate cell lines via ubiquitination and proteasome-dependent degradation.

Gong Y, Wang D, Dar JA, Singh P, Graham L, Liu W, Ai J, Xin Z, Guo Y, Wang Z.

Endocrinology. 2012 Dec;153(12):5716-25. doi: 10.1210/en.2012-1841. Epub 2012 Oct 5.

PMID:
23041672
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Regulation of Akt/FOXO3a/GSK-3beta/AR signaling network by isoflavone in prostate cancer cells.

Li Y, Wang Z, Kong D, Li R, Sarkar SH, Sarkar FH.

J Biol Chem. 2008 Oct 10;283(41):27707-16. doi: 10.1074/jbc.M802759200. Epub 2008 Aug 7.

PMID:
18687691
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

PC3, but not DU145, human prostate cancer cells retain the coregulators required for tumor suppressor ability of androgen receptor.

Litvinov IV, Antony L, Dalrymple SL, Becker R, Cheng L, Isaacs JT.

Prostate. 2006 Sep 1;66(12):1329-38.

PMID:
16835890
[PubMed - indexed for MEDLINE]
15.

Identification of kinases regulating prostate cancer cell growth using an RNAi phenotypic screen.

Whitworth H, Bhadel S, Ivey M, Conaway M, Spencer A, Hernan R, Holemon H, Gioeli D.

PLoS One. 2012;7(6):e38950. doi: 10.1371/journal.pone.0038950. Epub 2012 Jun 27.

PMID:
22761715
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Increased Akt signaling resulting from the loss of androgen responsiveness in prostate cancer.

Dulinska-Litewka J, McCubrey JA, Laidler P.

Curr Med Chem. 2013;20(1):144-57.

PMID:
23033951
[PubMed - indexed for MEDLINE]
17.

Down-regulation of Skp2 is correlated with p27-associated cell cycle arrest induced by phenylacetate in human prostate cancer cells.

Shibahara T, Onishi T, Franco OE, Arima K, Sugimura Y.

Anticancer Res. 2005 May-Jun;25(3B):1881-8.

PMID:
16158921
[PubMed - indexed for MEDLINE]
Free Article
18.

Increased PrLZ-mediated androgen receptor transactivation promotes prostate cancer growth at castration-resistant stage.

Li L, Xie H, Liang L, Gao Y, Zhang D, Fang L, Lee SO, Luo J, Chen X, Wang X, Chang LS, Yeh S, Wang Y, He D, Chang C.

Carcinogenesis. 2013 Feb;34(2):257-67. doi: 10.1093/carcin/bgs337. Epub 2012 Oct 26.

PMID:
23104178
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Vav3 enhances androgen receptor splice variant activity and is critical for castration-resistant prostate cancer growth and survival.

Peacock SO, Fahrenholtz CD, Burnstein KL.

Mol Endocrinol. 2012 Dec;26(12):1967-79. doi: 10.1210/me.2012-1165. Epub 2012 Sep 28.

PMID:
23023561
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Androgens as therapy for androgen receptor-positive castration-resistant prostate cancer.

Chuu CP, Kokontis JM, Hiipakka RA, Fukuchi J, Lin HP, Lin CY, Huo C, Su LC.

J Biomed Sci. 2011 Aug 23;18:63. doi: 10.1186/1423-0127-18-63. Review.

PMID:
21859492
[PubMed - indexed for MEDLINE]
Free PMC Article

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