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Items: 1 to 20 of 146

1.

Role of chaperone-mediated autophagy in degrading Huntington's disease-associated huntingtin protein.

Qi L, Zhang XD.

Acta Biochim Biophys Sin (Shanghai). 2014 Feb;46(2):83-91. doi: 10.1093/abbs/gmt133. Epub 2013 Dec 8. Review.

PMID:
24323530
2.

The role of chaperone-mediated autophagy in huntingtin degradation.

Qi L, Zhang XD, Wu JC, Lin F, Wang J, DiFiglia M, Qin ZH.

PLoS One. 2012;7(10):e46834. doi: 10.1371/journal.pone.0046834. Epub 2012 Oct 11.

3.

Constitutive upregulation of chaperone-mediated autophagy in Huntington's disease.

Koga H, Martinez-Vicente M, Arias E, Kaushik S, Sulzer D, Cuervo AM.

J Neurosci. 2011 Dec 14;31(50):18492-505. doi: 10.1523/JNEUROSCI.3219-11.2011.

4.

Structure of transmembrane domain of lysosome-associated membrane protein type 2a (LAMP-2A) reveals key features for substrate specificity in chaperone-mediated autophagy.

Rout AK, Strub MP, Piszczek G, Tjandra N.

J Biol Chem. 2014 Dec 19;289(51):35111-23. doi: 10.1074/jbc.M114.609446. Epub 2014 Oct 22.

5.

Chaperone-mediated autophagy.

Dice JF.

Autophagy. 2007 Jul-Aug;3(4):295-9. Epub 2007 Jul 15. Review.

PMID:
17404494
6.

The chaperone-mediated autophagy receptor organizes in dynamic protein complexes at the lysosomal membrane.

Bandyopadhyay U, Kaushik S, Varticovski L, Cuervo AM.

Mol Cell Biol. 2008 Sep;28(18):5747-63. doi: 10.1128/MCB.02070-07. Epub 2008 Jul 21.

7.

Lysosome membrane lipid microdomains: novel regulators of chaperone-mediated autophagy.

Kaushik S, Massey AC, Cuervo AM.

EMBO J. 2006 Sep 6;25(17):3921-33. Epub 2006 Aug 17.

8.
9.

Harnessing chaperone-mediated autophagy for the selective degradation of mutant huntingtin protein.

Bauer PO, Goswami A, Wong HK, Okuno M, Kurosawa M, Yamada M, Miyazaki H, Matsumoto G, Kino Y, Nagai Y, Nukina N.

Nat Biotechnol. 2010 Mar;28(3):256-63. doi: 10.1038/nbt.1608. Epub 2010 Feb 28.

PMID:
20190739
10.

Chaperone-mediated autophagy in aging and disease.

Massey AC, Zhang C, Cuervo AM.

Curr Top Dev Biol. 2006;73:205-35. Review.

PMID:
16782460
11.

Entering the lysosome through a transient gate by chaperone-mediated autophagy.

Bandyopadhyay U, Cuervo AM.

Autophagy. 2008 Nov;4(8):1101-3. Epub 2008 Nov 8.

12.

Degradation of AF1Q by chaperone-mediated autophagy.

Li P, Ji M, Lu F, Zhang J, Li H, Cui T, Li Wang X, Tang D, Ji C.

Exp Cell Res. 2014 Sep 10;327(1):48-56. doi: 10.1016/j.yexcr.2014.05.013. Epub 2014 May 29.

PMID:
24880125
13.

STUB1/CHIP is required for HIF1A degradation by chaperone-mediated autophagy.

Ferreira JV, Fôfo H, Bejarano E, Bento CF, Ramalho JS, Girão H, Pereira P.

Autophagy. 2013 Sep;9(9):1349-66. doi: 10.4161/auto.25190. Epub 2013 Jun 7.

PMID:
23880665
14.

Mechanisms of chaperone-mediated autophagy.

Majeski AE, Dice JF.

Int J Biochem Cell Biol. 2004 Dec;36(12):2435-44. Review.

PMID:
15325583
15.

Cardiomyocyte ryanodine receptor degradation by chaperone-mediated autophagy.

Pedrozo Z, Torrealba N, Fernández C, Gatica D, Toro B, Quiroga C, Rodriguez AE, Sanchez G, Gillette TG, Hill JA, Donoso P, Lavandero S.

Cardiovasc Res. 2013 May 1;98(2):277-85. doi: 10.1093/cvr/cvt029. Epub 2013 Feb 11.

16.

Chaperone-mediated autophagy: machinery, regulation and biological consequences.

Li W, Yang Q, Mao Z.

Cell Mol Life Sci. 2011 Mar;68(5):749-63. doi: 10.1007/s00018-010-0565-6. Epub 2010 Oct 26. Review.

PMID:
20976518
17.

Age-related increases of macroautophagy and chaperone-mediated autophagy in rat nucleus pulposus.

Ye W, Xu K, Huang D, Liang A, Peng Y, Zhu W, Li C.

Connect Tissue Res. 2011;52(6):472-8. doi: 10.3109/03008207.2011.564336. Epub 2011 May 18.

PMID:
21591930
18.

Degradation of misfolded proteins by autophagy: is it a strategy for Huntington's disease treatment?

Lin F, Qin ZH.

J Huntingtons Dis. 2013;2(2):149-57. doi: 10.3233/JHD-130052. Review.

PMID:
25063512
19.

Autophagy regulates the processing of amino terminal huntingtin fragments.

Qin ZH, Wang Y, Kegel KB, Kazantsev A, Apostol BL, Thompson LM, Yoder J, Aronin N, DiFiglia M.

Hum Mol Genet. 2003 Dec 15;12(24):3231-44. Epub 2003 Oct 21.

20.

Regional deficiencies in chaperone-mediated autophagy underlie α-synuclein aggregation and neurodegeneration.

Malkus KA, Ischiropoulos H.

Neurobiol Dis. 2012 Jun;46(3):732-44. doi: 10.1016/j.nbd.2012.03.017. Epub 2012 Mar 9.

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