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Results: 1 to 20 of 95

1.

Zebularine significantly sensitises MEC1 cells to external irradiation and radiopharmaceutical therapy when administered sequentially in vitro.

Bryan JN, Kumar SR, Jia F, Balkin ER, Lewis MR.

Cell Biol Int. 2014 Feb;38(2):187-97. doi: 10.1002/cbin.10215. Epub 2013 Dec 9.

PMID:
24323360
[PubMed - in process]
2.

Enhancement of in vitro and in vivo tumor cell radiosensitivity by the DNA methylation inhibitor zebularine.

Dote H, Cerna D, Burgan WE, Carter DJ, Cerra MA, Hollingshead MG, Camphausen K, Tofilon PJ.

Clin Cancer Res. 2005 Jun 15;11(12):4571-9.

PMID:
15958643
[PubMed - indexed for MEDLINE]
Free Article
3.

Effects of a novel DNA methyltransferase inhibitor Zebularine on human lens epithelial cells.

Zhou P, Lu Y, Sun XH.

Mol Vis. 2012;18:22-8. Epub 2012 Jan 10.

PMID:
22259221
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

The DNA methyltransferase inhibitor zebularine induces mitochondria-mediated apoptosis in gastric cancer cells in vitro and in vivo.

Tan W, Zhou W, Yu HG, Luo HS, Shen L.

Biochem Biophys Res Commun. 2013 Jan 4;430(1):250-5. doi: 10.1016/j.bbrc.2012.10.143. Epub 2012 Nov 17.

PMID:
23167995
[PubMed - indexed for MEDLINE]
5.

Epigenetic changes by zebularine leading to enhanced differentiation of human promyelocytic leukemia NB4 and KG1 cells.

Savickiene J, Treigyte G, Jonusiene V, Bruzaite R, Borutinskaite VV, Navakauskiene R.

Mol Cell Biochem. 2012 Jan;359(1-2):245-61. doi: 10.1007/s11010-011-1019-7. Epub 2011 Aug 13.

PMID:
21842375
[PubMed - indexed for MEDLINE]
6.

Zebularine inhibits human acute myeloid leukemia cell growth in vitro in association with p15INK4B demethylation and reexpression.

Scott SA, Lakshimikuttysamma A, Sheridan DP, Sanche SE, Geyer CR, DeCoteau JF.

Exp Hematol. 2007 Feb;35(2):263-73.

PMID:
17258075
[PubMed - indexed for MEDLINE]
7.

DNA methyltransferase inhibitor, zebularine, delays tumor growth and induces apoptosis in a genetically engineered mouse model of breast cancer.

Chen M, Shabashvili D, Nawab A, Yang SX, Dyer LM, Brown KD, Hollingshead M, Hunter KW, Kaye FJ, Hochwald SN, Marquez VE, Steeg P, Zajac-Kaye M.

Mol Cancer Ther. 2012 Feb;11(2):370-82. doi: 10.1158/1535-7163.MCT-11-0458. Epub 2011 Dec 27.

PMID:
22203734
[PubMed - indexed for MEDLINE]
Free Article
8.

DNA methyltransferase inhibitor zebularine inhibits human hepatic carcinoma cells proliferation and induces apoptosis.

Nakamura K, Aizawa K, Nakabayashi K, Kato N, Yamauchi J, Hata K, Tanoue A.

PLoS One. 2013;8(1):e54036. doi: 10.1371/journal.pone.0054036. Epub 2013 Jan 8.

PMID:
23320119
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Antimitogenic and chemosensitizing effects of the methylation inhibitor zebularine in ovarian cancer.

Balch C, Yan P, Craft T, Young S, Skalnik DG, Huang TH, Nephew KP.

Mol Cancer Ther. 2005 Oct;4(10):1505-14.

PMID:
16227399
[PubMed - indexed for MEDLINE]
Free Article
10.

Enhanced growth inhibition by combined DNA methylation/HDAC inhibitors in lung tumor cells with silenced CDKN2A.

Chen M, Voeller D, Marquez VE, Kaye FJ, Steeg PS, Giaccone G, Zajac-Kaye M.

Int J Oncol. 2010 Oct;37(4):963-71.

PMID:
20811718
[PubMed - indexed for MEDLINE]
11.

DNA-dependent protein kinase (DNA-PK)-deficient human glioblastoma cells are preferentially sensitized by Zebularine.

Meador JA, Su Y, Ravanat JL, Balajee AS.

Carcinogenesis. 2010 Feb;31(2):184-91. doi: 10.1093/carcin/bgp284. Epub 2009 Nov 23.

PMID:
19933707
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Inhibition of DNA methylation and reactivation of silenced genes by zebularine.

Cheng JC, Matsen CB, Gonzales FA, Ye W, Greer S, Marquez VE, Jones PA, Selker EU.

J Natl Cancer Inst. 2003 Mar 5;95(5):399-409.

PMID:
12618505
[PubMed - indexed for MEDLINE]
Free Article
13.

Zebularine induces prolonged apoptosis effects via the caspase-3/PARP pathway in head and neck cancer cells.

Napso T, Fares F.

Int J Oncol. 2014 Jun;44(6):1971-9. doi: 10.3892/ijo.2014.2386. Epub 2014 Apr 11.

PMID:
24728469
[PubMed - in process]
14.

The DNA methyltransferase inhibitors zebularine and decitabine induce mitochondria-mediated apoptosis and DNA damage in p53 mutant leukemic T cells.

Ruiz-Magaña MJ, Rodríguez-Vargas JM, Morales JC, Saldivia MA, Schulze-Osthoff K, Ruiz-Ruiz C.

Int J Cancer. 2012 Mar 1;130(5):1195-207. doi: 10.1002/ijc.26107. Epub 2011 Jul 21.

PMID:
21455989
[PubMed - indexed for MEDLINE]
15.

An integrated genomic and epigenomic approach predicts therapeutic response to zebularine in human liver cancer.

Andersen JB, Factor VM, Marquardt JU, Raggi C, Lee YH, Seo D, Conner EA, Thorgeirsson SS.

Sci Transl Med. 2010 Oct 20;2(54):54ra77. doi: 10.1126/scitranslmed.3001338.

PMID:
20962331
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Radiobiologic studies of radioimmunotherapy and external beam radiotherapy in vitro and in vivo in human renal cell carcinoma xenografts.

Ning S, Trisler K, Wessels BW, Knox SJ.

Cancer. 1997 Dec 15;80(12 Suppl):2519-28.

PMID:
9406705
[PubMed - indexed for MEDLINE]
17.

Regulation of TNFRSF6 (Fas) expression in ataxia telangiectasia cells by ionizing radiation.

Albanese J, Dainiak N.

Radiat Res. 2000 Dec;154(6):616-24.

PMID:
11096418
[PubMed - indexed for MEDLINE]
18.

Continuous zebularine treatment effectively sustains demethylation in human bladder cancer cells.

Cheng JC, Weisenberger DJ, Gonzales FA, Liang G, Xu GL, Hu YG, Marquez VE, Jones PA.

Mol Cell Biol. 2004 Feb;24(3):1270-8.

PMID:
14729971
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Differential expression of growth factors in irradiated mouse testes.

Mauduit C, Siah A, Foch M, Chapet O, Clippe S, Gerard JP, Benahmed M.

Int J Radiat Oncol Biol Phys. 2001 May 1;50(1):203-12.

PMID:
11316565
[PubMed - indexed for MEDLINE]
20.

The bioreductive agent RH1 and gamma-irradiation both cause G2/M cell cycle phase arrest and polyploidy in a p53-mutated human breast cancer cell line.

Kim JY, Kim CH, Stratford IJ, Patterson AV, Hendry JH.

Int J Radiat Oncol Biol Phys. 2004 Feb 1;58(2):376-85.

PMID:
14751506
[PubMed - indexed for MEDLINE]

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