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Items: 1 to 20 of 121

1.

Synthesis and biological evaluation of allylated and prenylated mono-carbonyl analogs of curcumin as anti-inflammatory agents.

Liu Z, Tang L, Zou P, Zhang Y, Wang Z, Fang Q, Jiang L, Chen G, Xu Z, Zhang H, Liang G.

Eur J Med Chem. 2014 Mar 3;74:671-82. doi: 10.1016/j.ejmech.2013.10.061. Epub 2013 Nov 1.

PMID:
24321865
2.

Discovery and evaluation of piperid-4-one-containing mono-carbonyl analogs of curcumin as anti-inflammatory agents.

Wu J, Zhang Y, Cai Y, Wang J, Weng B, Tang Q, Chen X, Pan Z, Liang G, Yang S.

Bioorg Med Chem. 2013 Jun 1;21(11):3058-65. doi: 10.1016/j.bmc.2013.03.057. Epub 2013 Mar 30.

PMID:
23611769
3.

Synthesis of mono-carbonyl analogues of curcumin and their effects on inhibition of cytokine release in LPS-stimulated RAW 264.7 macrophages.

Zhao C, Yang J, Wang Y, Liang D, Yang X, Li X, Wu J, Wu X, Yang S, Li X, Liang G.

Bioorg Med Chem. 2010 Apr 1;18(7):2388-93. doi: 10.1016/j.bmc.2010.03.001. Epub 2010 Mar 6.

PMID:
20338767
4.

Synthesis and evaluation of a series of novel asymmetrical curcumin analogs for the treatment of inflammation.

Zhang Y, Zhao L, Wu J, Jiang X, Dong L, Xu F, Zou P, Dai Y, Shan X, Yang S, Liang G.

Molecules. 2014 Jun 4;19(6):7287-307. doi: 10.3390/molecules19067287.

5.

Synthesis and anti-inflammatory evaluation of novel mono-carbonyl analogues of curcumin in LPS-stimulated RAW 264.7 macrophages.

Zhao C, Cai Y, He X, Li J, Zhang L, Wu J, Zhao Y, Yang S, Li X, Li W, Liang G.

Eur J Med Chem. 2010 Dec;45(12):5773-80. doi: 10.1016/j.ejmech.2010.09.037. Epub 2010 Oct 8.

PMID:
20934787
6.

Promising curcumin-based drug design: mono-carbonyl analogues of curcumin (MACs).

Zhao C, Liu Z, Liang G.

Curr Pharm Des. 2013;19(11):2114-35. Review.

PMID:
23116317
7.

Inhibition of LPS-induced production of inflammatory factors in the macrophages by mono-carbonyl analogues of curcumin.

Liang G, Zhou H, Wang Y, Gurley EC, Feng B, Chen L, Xiao J, Yang S, Li X.

J Cell Mol Med. 2009 Sep;13(9B):3370-9. doi: 10.1111/j.1582-4934.2009.00711.x. Epub 2009 Feb 20.

8.

Discovery and evaluation of novel anti-inflammatory derivatives of natural bioactive curcumin.

Zhang Y, Jiang X, Peng K, Chen C, Fu L, Wang Z, Feng J, Liu Z, Zhang H, Liang G, Pan Z.

Drug Des Devel Ther. 2014 Nov 4;8:2161-71. doi: 10.2147/DDDT.S69914. eCollection 2014.

9.

Synthesis and biological evaluation of a novel class of curcumin analogs as anti-inflammatory agents for prevention and treatment of sepsis in mouse model.

Zhao C, Zhang Y, Zou P, Wang J, He W, Shi D, Li H, Liang G, Yang S.

Drug Des Devel Ther. 2015 Mar 18;9:1663-78. doi: 10.2147/DDDT.S75862. eCollection 2015.

10.

Synthesis, crystal structure and anti-inflammatory properties of curcumin analogues.

Liang G, Yang S, Zhou H, Shao L, Huang K, Xiao J, Huang Z, Li X.

Eur J Med Chem. 2009 Feb;44(2):915-9. doi: 10.1016/j.ejmech.2008.01.031. Epub 2008 Feb 3.

PMID:
18336957
11.

Synthesis and optimization of novel allylated mono-carbonyl analogs of curcumin (MACs) act as potent anti-inflammatory agents against LPS-induced acute lung injury (ALI) in rats.

Zhu H, Xu T, Qiu C, Wu B, Zhang Y, Chen L, Xia Q, Li C, Zhou B, Liu Z, Liang G.

Eur J Med Chem. 2016 May 21;121:181-193. doi: 10.1016/j.ejmech.2016.05.041. [Epub ahead of print]

PMID:
27240273
12.

A novel synthetic mono-carbonyl analogue of curcumin, A13, exhibits anti-inflammatory effects in vivo by inhibition of inflammatory mediators.

Wang Y, Yu C, Pan Y, Yang X, Huang Y, Feng Z, Li X, Yang S, Liang G.

Inflammation. 2012 Apr;35(2):594-604. doi: 10.1007/s10753-011-9350-4.

PMID:
21614553
13.

Design, synthesis, and anticancer evaluation of long-chain alkoxylated mono-carbonyl analogues of curcumin.

Weng Q, Fu L, Chen G, Hui J, Song J, Feng J, Shi D, Cai Y, Ji J, Liang G.

Eur J Med Chem. 2015 Oct 20;103:44-55. doi: 10.1016/j.ejmech.2015.08.036. Epub 2015 Aug 19.

PMID:
26318057
14.

Design, synthesis and biological activity of novel asymmetric C66 analogs as anti-inflammatory agents for the treatment of acute lung injury.

Yu P, Dong L, Zhang Y, Chen W, Xu S, Wang Z, Shan X, Zhou J, Liu Z, Liang G.

Eur J Med Chem. 2015 Apr 13;94:436-46. doi: 10.1016/j.ejmech.2014.11.054. Epub 2015 Jan 7.

PMID:
25828826
15.

Discovery and evaluation of asymmetrical monocarbonyl analogs of curcumin as anti-inflammatory agents.

Zhang Y, Zhao C, He W, Wang Z, Fang Q, Xiao B, Liu Z, Liang G, Yang S.

Drug Des Devel Ther. 2014 Apr 4;8:373-82. doi: 10.2147/DDDT.S58168. eCollection 2014.

16.

Synthesis and biological evaluation of curcumin-like diarylpentanoid analogues for anti-inflammatory, antioxidant and anti-tyrosinase activities.

Lee KH, Ab Aziz FH, Syahida A, Abas F, Shaari K, Israf DA, Lajis NH.

Eur J Med Chem. 2009 Aug;44(8):3195-200. doi: 10.1016/j.ejmech.2009.03.020. Epub 2009 Mar 26.

PMID:
19359068
17.

Synthesis and biological evaluation of asymmetric indole curcumin analogs as potential anti-inflammatory and antioxidant agents.

Bandgar BP, Kinkar SN, Chavan HV, Jalde SS, Shaikh RU, Gacche RN.

J Enzyme Inhib Med Chem. 2014 Feb;29(1):7-11. doi: 10.3109/14756366.2012.743536. Epub 2013 Jan 28.

PMID:
23356406
18.

Synthesis and biological evaluation of novel curcumin analogs as anti-cancer and anti-angiogenesis agents.

Adams BK, Ferstl EM, Davis MC, Herold M, Kurtkaya S, Camalier RF, Hollingshead MG, Kaur G, Sausville EA, Rickles FR, Snyder JP, Liotta DC, Shoji M.

Bioorg Med Chem. 2004 Jul 15;12(14):3871-83.

PMID:
15210154
19.

Antitumor agents 247. New 4-ethoxycarbonylethyl curcumin analogs as potential antiandrogenic agents.

Lin L, Shi Q, Su CY, Shih CC, Lee KH.

Bioorg Med Chem. 2006 Apr 15;14(8):2527-34. Epub 2006 Jan 19.

PMID:
16427289
20.

Synthesis and anti-inflammatory activities of mono-carbonyl analogues of curcumin.

Liang G, Li X, Chen L, Yang S, Wu X, Studer E, Gurley E, Hylemon PB, Ye F, Li Y, Zhou H.

Bioorg Med Chem Lett. 2008 Feb 15;18(4):1525-9. doi: 10.1016/j.bmcl.2007.12.068. Epub 2008 Jan 1.

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