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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2003 1
2004 6
2005 1
2006 2
2007 5
2008 9
2009 12
2010 6
2011 7
2012 15
2013 20
2014 17
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2016 14
2017 4
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2019 8
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Similar articles for PMID: 24320998

150 results

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Page 1
Discovery of a novel class of dimeric Smac mimetics as potent IAP antagonists resulting in a clinical candidate for the treatment of cancer (AZD5582).
Hennessy EJ, Adam A, Aquila BM, Castriotta LM, Cook D, Hattersley M, Hird AW, Huntington C, Kamhi VM, Laing NM, Li D, MacIntyre T, Omer CA, Oza V, Patterson T, Repik G, Rooney MT, Saeh JC, Sha L, Vasbinder MM, Wang H, Whitston D. Hennessy EJ, et al. J Med Chem. 2013 Dec 27;56(24):9897-919. doi: 10.1021/jm401075x. Epub 2013 Dec 13. J Med Chem. 2013. PMID: 24320998
Dimeric Smac mimetics/IAP inhibitors as in vivo-active pro-apoptotic agents. Part II: Structural and biological characterization.
Lecis D, Mastrangelo E, Belvisi L, Bolognesi M, Civera M, Cossu F, De Cesare M, Delia D, Drago C, Manenti G, Manzoni L, Milani M, Moroni E, Perego P, Potenza D, Rizzo V, Scavullo C, Scolastico C, Servida F, Vasile F, Seneci P. Lecis D, et al. Bioorg Med Chem. 2012 Nov 15;20(22):6709-23. doi: 10.1016/j.bmc.2012.09.041. Epub 2012 Sep 24. Bioorg Med Chem. 2012. PMID: 23062821
ASTX660, a Novel Non-peptidomimetic Antagonist of cIAP1/2 and XIAP, Potently Induces TNFα-Dependent Apoptosis in Cancer Cell Lines and Inhibits Tumor Growth.
Ward GA, Lewis EJ, Ahn JS, Johnson CN, Lyons JF, Martins V, Munck JM, Rich SJ, Smyth T, Thompson NT, Williams PA, Wilsher NE, Wallis NG, Chessari G. Ward GA, et al. Mol Cancer Ther. 2018 Jul;17(7):1381-1391. doi: 10.1158/1535-7163.MCT-17-0848. Epub 2018 Apr 25. Mol Cancer Ther. 2018. PMID: 29695633
Recognition of Smac-mimetic compounds by the BIR domain of cIAP1.
Cossu F, Malvezzi F, Canevari G, Mastrangelo E, Lecis D, Delia D, Seneci P, Scolastico C, Bolognesi M, Milani M. Cossu F, et al. Protein Sci. 2010 Dec;19(12):2418-29. doi: 10.1002/pro.523. Protein Sci. 2010. PMID: 20954235 Free PMC article.
Smac mimetics as IAP antagonists.
Fulda S. Fulda S. Semin Cell Dev Biol. 2015 Mar;39:132-8. doi: 10.1016/j.semcdb.2014.12.005. Epub 2014 Dec 27. Semin Cell Dev Biol. 2015. PMID: 25550219 Review.
150 results