Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Results: 1 to 20 of 109

1.

Novel antimitotic activity of 2-hydroxy-4-methoxy-2',3'-benzochalcone (HymnPro) through the inhibition of tubulin polymerization.

Shin SY, Kim JH, Yoon H, Choi YK, Koh D, Lim Y, Lee YH.

J Agric Food Chem. 2013 Dec 26;61(51):12588-97. doi: 10.1021/jf4034688. Epub 2013 Dec 12.

PMID:
24308485
[PubMed - indexed for MEDLINE]
2.

Pyrrolotetrazinones deazaanalogues of temozolomide induce apoptosis in Jurkat cell line: involvement of tubulin polymerization inhibition.

Viola G, Cecconet L, Leszl A, Basso G, Brun P, Salvador A, Dall'Acqua F, Diana P, Barraja P, Cirrincione G.

Cancer Chemother Pharmacol. 2009 Nov;64(6):1235-51. doi: 10.1007/s00280-009-0994-9. Epub 2009 Apr 11.

PMID:
19363609
[PubMed - indexed for MEDLINE]
3.

Arsenic trioxide produces polymerization of microtubules and mitotic arrest before apoptosis in human tumor cell lines.

Ling YH, Jiang JD, Holland JF, Perez-Soler R.

Mol Pharmacol. 2002 Sep;62(3):529-38.

PMID:
12181429
[PubMed - indexed for MEDLINE]
Free Article
4.

Double blockade of cell cycle at g(1)-s transition and m phase by 3-iodoacetamido benzoyl ethyl ester, a new type of tubulin ligand.

Jiang JD, Denner L, Ling YH, Li JN, Davis A, Wang Y, Li Y, Roboz J, Wang LG, Perez-Soler R, Marcelli M, Bekesi G, Holland JF.

Cancer Res. 2002 Nov 1;62(21):6080-8.

PMID:
12414632
[PubMed - indexed for MEDLINE]
Free Article
5.

Investigation of anti-tumor mechanisms of K2154: characterization of tubulin isotypes, mitotic arrest and apoptotic machinery.

Lu PH, Kung FL, Kuo SC, Chueh SC, Guh JH.

Naunyn Schmiedebergs Arch Pharmacol. 2006 Dec;374(3):223-33. Epub 2006 Nov 11.

PMID:
17102938
[PubMed - indexed for MEDLINE]
6.

DAT-230, a Novel Microtubule Inhibitor, Induced Aberrant Mitosis and Apoptosis in SGC-7901 Cells.

Qiao F, Zuo D, Wang H, Li Z, Qi H, Zhang W, Wu Y.

Biol Pharm Bull. 2013;36(2):193-201.

PMID:
23370351
[PubMed - indexed for MEDLINE]
Free Article
7.

Induction of apoptosis by the garlic-derived compound S-allylmercaptocysteine (SAMC) is associated with microtubule depolymerization and c-Jun NH(2)-terminal kinase 1 activation.

Xiao D, Pinto JT, Soh JW, Deguchi A, Gundersen GG, Palazzo AF, Yoon JT, Shirin H, Weinstein IB.

Cancer Res. 2003 Oct 15;63(20):6825-37.

PMID:
14583480
[PubMed - indexed for MEDLINE]
Free Article
8.

Antimitotic effect of the retinoid 4-oxo-fenretinide through inhibition of tubulin polymerization: a novel mechanism of retinoid growth-inhibitory activity.

Appierto V, Tiberio P, Cavadini E, Casalini P, Cappelletti G, Formelli F.

Mol Cancer Ther. 2009 Dec;8(12):3360-8. doi: 10.1158/1535-7163.MCT-09-0798. Epub .

PMID:
19996280
[PubMed - indexed for MEDLINE]
Free Article
9.

BPR0L075, a novel synthetic indole compound with antimitotic activity in human cancer cells, exerts effective antitumoral activity in vivo.

Kuo CC, Hsieh HP, Pan WY, Chen CP, Liou JP, Lee SJ, Chang YL, Chen LT, Chen CT, Chang JY.

Cancer Res. 2004 Jul 1;64(13):4621-8.

PMID:
15231674
[PubMed - indexed for MEDLINE]
Free Article
10.

(E)-4-aryl-4-oxo-2-butenoic acid amides, chalcone-aroylacrylic acid chimeras: design, antiproliferative activity and inhibition of tubulin polymerization.

Vitorović-Todorović MD, Erić-Nikolić A, Kolundžija B, Hamel E, Ristić S, Juranić IO, Drakulić BJ.

Eur J Med Chem. 2013 Apr;62:40-50. doi: 10.1016/j.ejmech.2013.01.006. Epub 2013 Jan 11.

PMID:
23353745
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Anti-tumor activity and mechanisms of a novel vascular disrupting agent, (Z)-3,4',5-trimethoxylstilbene-3'-O-phosphate disodium (M410).

Cai YC, Zou Y, Ye YL, Sun HY, Su QG, Wang ZX, Zeng ZL, Xian LJ.

Invest New Drugs. 2011 Apr;29(2):300-11. doi: 10.1007/s10637-009-9366-x. Epub 2009 Dec 11.

PMID:
20012336
[PubMed - indexed for MEDLINE]
12.

JNK inhibitor SP600125 promotes the formation of polymerized tubulin, leading to G2/M phase arrest, endoreduplication, and delayed apoptosis.

Moon DO, Kim MO, Kang CH, Lee JD, Choi YH, Kim GY.

Exp Mol Med. 2009 Sep 30;41(9):665-77. doi: 10.3858/emm.2009.41.9.073.

PMID:
19478553
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

6,7-Dimethoxy-3-(3-methoxyphenyl)isoquinolin-1-amine induces mitotic arrest and apoptotic cell death through the activation of spindle assembly checkpoint in human cervical cancer cells.

Chung KS, Choi HE, Shin JS, Cho YW, Choi JH, Cho WJ, Lee KT.

Carcinogenesis. 2013 Aug;34(8):1852-60. doi: 10.1093/carcin/bgt133. Epub 2013 Apr 24.

PMID:
23615402
[PubMed - indexed for MEDLINE]
Free Article
14.

MJ-29 inhibits tubulin polymerization, induces mitotic arrest, and triggers apoptosis via cyclin-dependent kinase 1-mediated Bcl-2 phosphorylation in human leukemia U937 cells.

Yang JS, Hour MJ, Huang WW, Lin KL, Kuo SC, Chung JG.

J Pharmacol Exp Ther. 2010 Aug;334(2):477-88. doi: 10.1124/jpet.109.165415. Epub 2010 May 12.

PMID:
20463006
[PubMed - indexed for MEDLINE]
Free Article
15.

Design, synthesis and biological evaluation of millepachine derivatives as a new class of tubulin polymerization inhibitors.

Wang G, Peng F, Cao D, Yang Z, Han X, Liu J, Wu W, He L, Ma L, Chen J, Sang Y, Xiang M, Peng A, Wei Y, Chen L.

Bioorg Med Chem. 2013 Nov 1;21(21):6844-54. doi: 10.1016/j.bmc.2013.02.002. Epub 2013 Feb 13.

PMID:
23993668
[PubMed - indexed for MEDLINE]
16.

Structure-based virtual screening of novel tubulin inhibitors and their characterization as anti-mitotic agents.

Kim ND, Park ES, Kim YH, Moon SK, Lee SS, Ahn SK, Yu DY, No KT, Kim KH.

Bioorg Med Chem. 2010 Oct 1;18(19):7092-100. doi: 10.1016/j.bmc.2010.07.072. Epub 2010 Aug 6.

PMID:
20810285
[PubMed - indexed for MEDLINE]
17.

Mechanisms by which synthetic 6,7-annulated-4-substituted indole compounds with anti-proliferative activity disrupt mitosis and block cytokinesis in human HL-60 tumor cells in vitro.

Perchellet JP, Perchellet EM, Singh CR, Monnett MT, Studer ER, Thornton PD, Brown N, Hill D, Neuenswander B, Lushington GH, Santini C, Buszek KR.

Anticancer Res. 2014 Apr;34(4):1643-55.

PMID:
24692693
[PubMed - indexed for MEDLINE]
18.

Design and biological evaluation of novel tubulin inhibitors as antimitotic agents using a pharmacophore binding model with tubulin.

Kim do Y, Kim KH, Kim ND, Lee KY, Han CK, Yoon JH, Moon SK, Lee SS, Seong BL.

J Med Chem. 2006 Sep 21;49(19):5664-70.

PMID:
16970393
[PubMed - indexed for MEDLINE]
19.

Synthesis and biological evaluation of 2-(3',4',5'-trimethoxybenzoyl)-3-aryl/arylaminobenzo[b]thiophene derivatives as a novel class of antiproliferative agents.

Romagnoli R, Baraldi PG, Cara CL, Hamel E, Basso G, Bortolozzi R, Viola G.

Eur J Med Chem. 2010 Dec;45(12):5781-91. doi: 10.1016/j.ejmech.2010.09.038. Epub 2010 Oct 8.

PMID:
20933308
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

A new synthetic 2'-hydroxy-2,4,6-trimethoxy-5',6'-naphthochalcone induces G2/M cell cycle arrest and apoptosis by disrupting the microtubular network of human colon cancer cells.

Lee JM, Lee MS, Koh D, Lee YH, Lim Y, Shin SY.

Cancer Lett. 2014 Sep 1. pii: S0304-3835(14)00494-7. doi: 10.1016/j.canlet.2014.08.041. [Epub ahead of print]

PMID:
25193463
[PubMed - as supplied by publisher]

Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Supplemental Content

Write to the Help Desk