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Items: 1 to 20 of 155

1.

MPYS/STING-mediated TNF-α, not type I IFN, is essential for the mucosal adjuvant activity of (3'-5')-cyclic-di-guanosine-monophosphate in vivo.

Blaauboer SM, Gabrielle VD, Jin L.

J Immunol. 2014 Jan 1;192(1):492-502. doi: 10.4049/jimmunol.1301812. Epub 2013 Dec 4.

2.

MPYS is required for IFN response factor 3 activation and type I IFN production in the response of cultured phagocytes to bacterial second messengers cyclic-di-AMP and cyclic-di-GMP.

Jin L, Hill KK, Filak H, Mogan J, Knowles H, Zhang B, Perraud AL, Cambier JC, Lenz LL.

J Immunol. 2011 Sep 1;187(5):2595-601. doi: 10.4049/jimmunol.1100088. Epub 2011 Aug 3.

3.

The mucosal adjuvant cyclic di-GMP enhances antigen uptake and selectively activates pinocytosis-efficient cells in vivo.

Blaauboer SM, Mansouri S, Tucker HR, Wang HL, Gabrielle VD, Jin L.

Elife. 2015 Apr 21;4. doi: 10.7554/eLife.06670.

4.

STING is a direct innate immune sensor of cyclic di-GMP.

Burdette DL, Monroe KM, Sotelo-Troha K, Iwig JS, Eckert B, Hyodo M, Hayakawa Y, Vance RE.

Nature. 2011 Sep 25;478(7370):515-8. doi: 10.1038/nature10429.

5.

Cytosolic-DNA-mediated, STING-dependent proinflammatory gene induction necessitates canonical NF-κB activation through TBK1.

Abe T, Barber GN.

J Virol. 2014 May;88(10):5328-41. doi: 10.1128/JVI.00037-14. Epub 2014 Mar 5.

6.

Single nucleotide polymorphisms of human STING can affect innate immune response to cyclic dinucleotides.

Yi G, Brendel VP, Shu C, Li P, Palanathan S, Cheng Kao C.

PLoS One. 2013 Oct 21;8(10):e77846. doi: 10.1371/journal.pone.0077846. eCollection 2013.

7.

Modified vaccinia virus Ankara triggers type I IFN production in murine conventional dendritic cells via a cGAS/STING-mediated cytosolic DNA-sensing pathway.

Dai P, Wang W, Cao H, Avogadri F, Dai L, Drexler I, Joyce JA, Li XD, Chen Z, Merghoub T, Shuman S, Deng L.

PLoS Pathog. 2014 Apr 17;10(4):e1003989. doi: 10.1371/journal.ppat.1003989. eCollection 2014 Apr.

8.

Generation of Th1 and Th2 chemokines by human eosinophils: evidence for a critical role of TNF-alpha.

Liu LY, Bates ME, Jarjour NN, Busse WW, Bertics PJ, Kelly EA.

J Immunol. 2007 Oct 1;179(7):4840-8.

10.

The N-ethyl-N-nitrosourea-induced Goldenticket mouse mutant reveals an essential function of Sting in the in vivo interferon response to Listeria monocytogenes and cyclic dinucleotides.

Sauer JD, Sotelo-Troha K, von Moltke J, Monroe KM, Rae CS, Brubaker SW, Hyodo M, Hayakawa Y, Woodward JJ, Portnoy DA, Vance RE.

Infect Immun. 2011 Feb;79(2):688-94. doi: 10.1128/IAI.00999-10. Epub 2010 Nov 22.

11.

Cyclic GMP-AMP displays mucosal adjuvant activity in mice.

Škrnjug I, Guzmán CA, Rueckert C.

PLoS One. 2014 Oct 8;9(10):e110150. doi: 10.1371/journal.pone.0110150. eCollection 2014. Erratum in: PLoS One. 2015;10(3):e0123605. Ruecker, Christine [corrected to Rueckert, Christine].

12.

Activation with CpG-A and CpG-B oligonucleotides reveals two distinct regulatory pathways of type I IFN synthesis in human plasmacytoid dendritic cells.

Kerkmann M, Rothenfusser S, Hornung V, Towarowski A, Wagner M, Sarris A, Giese T, Endres S, Hartmann G.

J Immunol. 2003 May 1;170(9):4465-74.

13.

Cholera toxin promotes the induction of regulatory T cells specific for bystander antigens by modulating dendritic cell activation.

Lavelle EC, McNeela E, Armstrong ME, Leavy O, Higgins SC, Mills KH.

J Immunol. 2003 Sep 1;171(5):2384-92.

14.

TLR9 and STING agonists synergistically induce innate and adaptive type-II IFN.

Temizoz B, Kuroda E, Ohata K, Jounai N, Ozasa K, Kobiyama K, Aoshi T, Ishii KJ.

Eur J Immunol. 2015 Apr;45(4):1159-69. doi: 10.1002/eji.201445132. Epub 2015 Feb 5.

15.

Adjuvant activities of immune response modifier R-848: comparison with CpG ODN.

Vasilakos JP, Smith RM, Gibson SJ, Lindh JM, Pederson LK, Reiter MJ, Smith MH, Tomai MA.

Cell Immunol. 2000 Aug 25;204(1):64-74.

PMID:
11006019
16.

A new adjuvant delivery system 'cyclic di-GMP/YSK05 liposome' for cancer immunotherapy.

Miyabe H, Hyodo M, Nakamura T, Sato Y, Hayakawa Y, Harashima H.

J Control Release. 2014 Jun 28;184:20-7. doi: 10.1016/j.jconrel.2014.04.004. Epub 2014 Apr 13.

PMID:
24727060
17.

Cutting edge: DNA sensing via the STING adaptor in myeloid dendritic cells induces potent tolerogenic responses.

Huang L, Li L, Lemos H, Chandler PR, Pacholczyk G, Baban B, Barber GN, Hayakawa Y, McGaha TL, Ravishankar B, Munn DH, Mellor AL.

J Immunol. 2013 Oct 1;191(7):3509-13. doi: 10.4049/jimmunol.1301419. Epub 2013 Aug 28.

18.

Bis-(3',5')-cyclic dimeric adenosine monophosphate: strong Th1/Th2/Th17 promoting mucosal adjuvant.

Ebensen T, Libanova R, Schulze K, Yevsa T, Morr M, Guzmán CA.

Vaccine. 2011 Jul 18;29(32):5210-20. doi: 10.1016/j.vaccine.2011.05.026. Epub 2011 May 25.

PMID:
21619907
19.

Vaccinia virus E3 suppresses expression of diverse cytokines through inhibition of the PKR, NF-kappaB, and IRF3 pathways.

Myskiw C, Arsenio J, van Bruggen R, Deschambault Y, Cao J.

J Virol. 2009 Jul;83(13):6757-68. doi: 10.1128/JVI.02570-08. Epub 2009 Apr 15.

20.

The use of a mutant TNF-alpha as a vaccine adjuvant for the induction of mucosal immune responses.

Kayamuro H, Abe Y, Yoshioka Y, Katayama K, Nomura T, Yoshida T, Yamashita K, Yoshikawa T, Kawai Y, Mayumi T, Hiroi T, Itoh N, Nagano K, Kamada H, Tsunoda S, Tsutsumi Y.

Biomaterials. 2009 Oct;30(29):5869-76. doi: 10.1016/j.biomaterials.2009.07.009. Epub 2009 Jul 30.

PMID:
19646748
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