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Items: 1 to 20 of 99

1.

A2E-mediated photochemical modification to fibronectin and its implications to age-related changes in Bruch's membrane.

Thao MT, Renfus DJ, Dillon J, Gaillard ER.

Photochem Photobiol. 2014 Mar-Apr;90(2):329-34. doi: 10.1111/php.12200. Epub 2013 Nov 28.

PMID:
24303925
2.

Modifications to the basement membrane protein laminin using glycolaldehyde and A2E: a model for aging in Bruch's membrane.

Murdaugh LS, Dillon J, Gaillard ER.

Exp Eye Res. 2009 Aug;89(2):187-92. doi: 10.1016/j.exer.2009.03.021. Epub 2009 Apr 7.

PMID:
19358843
3.

Age-related accumulation of 3-nitrotyrosine and nitro-A2E in human Bruch's membrane.

Murdaugh LS, Wang Z, Del Priore LV, Dillon J, Gaillard ER.

Exp Eye Res. 2010 May;90(5):564-71. doi: 10.1016/j.exer.2010.01.014. Epub 2010 Feb 12.

PMID:
20153746
4.

Characterization of peroxy-A2E and furan-A2E photooxidation products and detection in human and mouse retinal pigment epithelial cell lipofuscin.

Jang YP, Matsuda H, Itagaki Y, Nakanishi K, Sparrow JR.

J Biol Chem. 2005 Dec 2;280(48):39732-9. Epub 2005 Sep 26.

5.

Advanced glycation end product (AGE) accumulation on Bruch's membrane: links to age-related RPE dysfunction.

Glenn JV, Mahaffy H, Wu K, Smith G, Nagai R, Simpson DA, Boulton ME, Stitt AW.

Invest Ophthalmol Vis Sci. 2009 Jan;50(1):441-51. doi: 10.1167/iovs.08-1724. Epub 2008 Aug 1.

PMID:
18676633
6.

Compositional studies of human RPE lipofuscin: mechanisms of molecular modifications.

Murdaugh LS, Mandal S, Dill AE, Dillon J, Simon JD, Gaillard ER.

J Mass Spectrom. 2011 Jan;46(1):90-5. doi: 10.1002/jms.1865.

PMID:
21182214
7.

Overexpression of integrin alpha6 and beta4 enhances adhesion and proliferation of human retinal pigment epithelial cells on layers of porcine Bruch's membrane.

Fang IM, Yang CH, Yang CM, Chen MS.

Exp Eye Res. 2009 Jan;88(1):12-21. doi: 10.1016/j.exer.2008.09.019. Epub 2008 Oct 10.

PMID:
18955047
8.

Structural characterization of bisretinoid A2E photocleavage products and implications for age-related macular degeneration.

Wu Y, Yanase E, Feng X, Siegel MM, Sparrow JR.

Proc Natl Acad Sci U S A. 2010 Apr 20;107(16):7275-80. doi: 10.1073/pnas.0913112107. Epub 2010 Apr 5.

9.

The photochemical oxidation of A2E results in the formation of a 5,8,5',8'-bis-furanoid oxide.

Dillon J, Wang Z, Avalle LB, Gaillard ER.

Exp Eye Res. 2004 Oct;79(4):537-42.

PMID:
15381037
11.

Photooxidation of A2-PE, a photoreceptor outer segment fluorophore, and protection by lutein and zeaxanthin.

Kim SR, Nakanishi K, Itagaki Y, Sparrow JR.

Exp Eye Res. 2006 May;82(5):828-39. Epub 2005 Dec 20.

PMID:
16364293
12.

Lipofuscin and N-retinylidene-N-retinylethanolamine (A2E) accumulate in retinal pigment epithelium in absence of light exposure: their origin is 11-cis-retinal.

Boyer NP, Higbee D, Currin MB, Blakeley LR, Chen C, Ablonczy Z, Crouch RK, Koutalos Y.

J Biol Chem. 2012 Jun 22;287(26):22276-86. doi: 10.1074/jbc.M111.329235. Epub 2012 May 8.

13.
14.

Complement activation by photooxidation products of A2E, a lipofuscin constituent of the retinal pigment epithelium.

Zhou J, Jang YP, Kim SR, Sparrow JR.

Proc Natl Acad Sci U S A. 2006 Oct 31;103(44):16182-7. Epub 2006 Oct 23.

15.

Early changes in gene expression induced by blue light irradiation of A2E-laden retinal pigment epithelial cells.

van der Burght BW, Hansen M, Olsen J, Zhou J, Wu Y, Nissen MH, Sparrow JR.

Acta Ophthalmol. 2013 Nov;91(7):e537-45. doi: 10.1111/aos.12146. Epub 2013 Jun 7.

16.

Topographic and age-related changes of the retinal epithelium and Bruch's membrane of rhesus monkeys.

Gouras P, Ivert L, Neuringer M, Mattison JA.

Graefes Arch Clin Exp Ophthalmol. 2010 Jul;248(7):973-84. doi: 10.1007/s00417-010-1325-x. Epub 2010 Mar 2.

17.

Light-induced deposits in Bruch's membrane of protoporphyric mice.

Gottsch JD, Bynoe LA, Harlan JB, Rencs EV, Green WR.

Arch Ophthalmol. 1993 Jan;111(1):126-9.

PMID:
8424710
18.

Interaction of pyridinium bis-retinoid (A2E) with bilayer lipid membranes.

Sokolov VS, Sokolenko EA, Sokolov AV, Dontsov AE, Chizmadzhev YA, Ostrovsky MA.

J Photochem Photobiol B. 2007 Feb 1;86(2):177-85. Epub 2006 Oct 27.

PMID:
17070694
19.

Spectral profiling of autofluorescence associated with lipofuscin, Bruch's Membrane, and sub-RPE deposits in normal and AMD eyes.

Marmorstein AD, Marmorstein LY, Sakaguchi H, Hollyfield JG.

Invest Ophthalmol Vis Sci. 2002 Jul;43(7):2435-41.

PMID:
12091448
20.

[Adhesive properties of basal membranes of Bruch's membrane. Immunohistochemical studies of age-dependent changes in adhesive molecules and lipid deposits].

Pauleikhoff D, Wojteki S, Müller D, Bornfeld N, Heiligenhaus A.

Ophthalmologe. 2000 Apr;97(4):243-50. German.

PMID:
10827458
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