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Results: 1 to 20 of 101

1.

A targeted in vivo SILAC approach for quantification of drug metabolism enzymes: regulation by the constitutive androstane receptor.

Macleod AK, Zang T, Riches Z, Henderson CJ, Wolf CR, Huang JT.

J Proteome Res. 2014 Feb 7;13(2):866-74. doi: 10.1021/pr400897t. Epub 2013 Dec 12.

PMID:
24303842
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Role of constitutive androstane receptor in Toll-like receptor-mediated regulation of gene expression of hepatic drug-metabolizing enzymes and transporters.

Shah P, Guo T, Moore DD, Ghose R.

Drug Metab Dispos. 2014 Jan;42(1):172-81. doi: 10.1124/dmd.113.053850. Epub 2013 Nov 5.

PMID:
24194512
[PubMed - indexed for MEDLINE]
3.

Pharmacogenomics, regulation and signaling pathways of phase I and II drug metabolizing enzymes.

Rushmore TH, Kong AN.

Curr Drug Metab. 2002 Oct;3(5):481-90. Review.

PMID:
12369894
[PubMed - indexed for MEDLINE]
4.

Differential role of Toll-interleukin 1 receptor domain-containing adaptor protein in Toll-like receptor 2-mediated regulation of gene expression of hepatic cytokines and drug-metabolizing enzymes.

Ghose R, Guo T, Vallejo JG, Gandhi A.

Drug Metab Dispos. 2011 May;39(5):874-81. doi: 10.1124/dmd.110.037382. Epub 2011 Feb 8.

PMID:
21303924
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Sterol regulatory element binding protein 1 interacts with pregnane X receptor and constitutive androstane receptor and represses their target genes.

Roth A, Looser R, Kaufmann M, Meyer UA.

Pharmacogenet Genomics. 2008 Apr;18(4):325-37. doi: 10.1097/FPC.0b013e3282f706e0.

PMID:
18334917
[PubMed - indexed for MEDLINE]
6.

The nuclear receptors pregnane X receptor and constitutive androstane receptor contribute to the impact of fipronil on hepatic gene expression linked to thyroid hormone metabolism.

Roques BB, Leghait J, Lacroix MZ, Lasserre F, Pineau T, Viguié C, Martin PG.

Biochem Pharmacol. 2013 Oct 1;86(7):997-1039. doi: 10.1016/j.bcp.2013.08.012. Epub 2013 Aug 17.

PMID:
23962444
[PubMed - indexed for MEDLINE]
Free Article
7.

Induction of phase I, II and III drug metabolism/transport by xenobiotics.

Xu C, Li CY, Kong AN.

Arch Pharm Res. 2005 Mar;28(3):249-68. Review.

PMID:
15832810
[PubMed - indexed for MEDLINE]
8.

Altered expression of nuclear receptors affects the expression of metabolic enzymes and transporters in a rat model of cholestasis.

Hasegawa Y, Kishimoto S, Takahashi H, Inotsume N, Takeuchi Y, Fukushima S.

Biol Pharm Bull. 2009 Dec;32(12):2046-52.

PMID:
19952426
[PubMed - indexed for MEDLINE]
Free Article
9.

PTMScan direct: identification and quantification of peptides from critical signaling proteins by immunoaffinity enrichment coupled with LC-MS/MS.

Stokes MP, Farnsworth CL, Moritz A, Silva JC, Jia X, Lee KA, Guo A, Polakiewicz RD, Comb MJ.

Mol Cell Proteomics. 2012 May;11(5):187-201. doi: 10.1074/mcp.M111.015883. Epub 2012 Feb 9.

PMID:
22322096
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Nuclear receptors in the multidrug resistance through the regulation of drug-metabolizing enzymes and drug transporters.

Chen Y, Tang Y, Guo C, Wang J, Boral D, Nie D.

Biochem Pharmacol. 2012 Apr 15;83(8):1112-26. doi: 10.1016/j.bcp.2012.01.030. Epub 2012 Feb 4. Review.

PMID:
22326308
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Methadone induces the expression of hepatic drug-metabolizing enzymes through the activation of pregnane X receptor and constitutive androstane receptor.

Tolson AH, Li H, Eddington ND, Wang H.

Drug Metab Dispos. 2009 Sep;37(9):1887-94. doi: 10.1124/dmd.109.027854. Epub 2009 Jun 11.

PMID:
19520773
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

The role of constitutive androstane receptor in oxazaphosphorine-mediated induction of drug-metabolizing enzymes in human hepatocytes.

Wang D, Li L, Fuhrman J, Ferguson S, Wang H.

Pharm Res. 2011 Aug;28(8):2034-44. doi: 10.1007/s11095-011-0429-2. Epub 2011 Apr 13.

PMID:
21487929
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Development of a pharmaceutical hepatotoxicity biomarker panel using a discovery to targeted proteomics approach.

Collins BC, Miller CA, Sposny A, Hewitt P, Wells M, Gallagher WM, Pennington SR.

Mol Cell Proteomics. 2012 Aug;11(8):394-410. doi: 10.1074/mcp.M111.016493. Epub 2012 Apr 23.

PMID:
22527513
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Functional crosstalk of CAR-LXR and ROR-LXR in drug metabolism and lipid metabolism.

Xiao L, Xie X, Zhai Y.

Adv Drug Deliv Rev. 2010 Oct 30;62(13):1316-21. doi: 10.1016/j.addr.2010.07.006. Epub 2010 Jul 24. Review.

PMID:
20659512
[PubMed - indexed for MEDLINE]
15.

Androgen glucuronides analysis by liquid chromatography tandem-mass spectrometry: could it raise new perspectives in the diagnostic field of hormone-dependent malignancies?

Kalogera E, Pistos C, Provatopoulou X, Athanaselis S, Spiliopoulou C, Gounaris A.

J Chromatogr B Analyt Technol Biomed Life Sci. 2013 Dec 1;940:24-34. doi: 10.1016/j.jchromb.2013.09.022. Epub 2013 Sep 27. Review.

PMID:
24140653
[PubMed - indexed for MEDLINE]
16.

The effect of Nrf2 knockout on the constitutive expression of drug metabolizing enzymes and transporters in C57Bl/6 mice livers.

Anwar-Mohamed A, Degenhardt OS, El Gendy MA, Seubert JM, Kleeberger SR, El-Kadi AO.

Toxicol In Vitro. 2011 Jun;25(4):785-95. doi: 10.1016/j.tiv.2011.01.014. Epub 2011 Jan 31.

PMID:
21281708
[PubMed - indexed for MEDLINE]
17.

The role of the nuclear receptor constitutive androstane receptor in the pathogenesis of non-alcoholic steatohepatitis.

Yamazaki Y, Kakizaki S, Horiguchi N, Sohara N, Sato K, Takagi H, Mori M, Negishi M.

Gut. 2007 Apr;56(4):565-74. Epub 2006 Sep 1.

PMID:
16950832
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Role of orphan nuclear receptors in the regulation of drug-metabolising enzymes.

Wang H, LeCluyse EL.

Clin Pharmacokinet. 2003;42(15):1331-57. Review.

PMID:
14674787
[PubMed - indexed for MEDLINE]
19.

Coordinated regulation of hepatic phase I and II drug-metabolizing genes and transporters using AhR-, CAR-, PXR-, PPARα-, and Nrf2-null mice.

Aleksunes LM, Klaassen CD.

Drug Metab Dispos. 2012 Jul;40(7):1366-79. doi: 10.1124/dmd.112.045112. Epub 2012 Apr 11.

PMID:
22496397
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Perfluorocarboxylic acids induce cytochrome P450 enzymes in mouse liver through activation of PPAR-alpha and CAR transcription factors.

Cheng X, Klaassen CD.

Toxicol Sci. 2008 Nov;106(1):29-36. doi: 10.1093/toxsci/kfn147. Epub 2008 Jul 22.

PMID:
18648086
[PubMed - indexed for MEDLINE]
Free PMC Article
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