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Items: 1 to 20 of 135

1.

Gata2 cis-element is required for hematopoietic stem cell generation in the mammalian embryo.

Gao X, Johnson KD, Chang YI, Boyer ME, Dewey CN, Zhang J, Bresnick EH.

J Exp Med. 2013 Dec 16;210(13):2833-42. doi: 10.1084/jem.20130733. Epub 2013 Dec 2.

2.

Hes repressors are essential regulators of hematopoietic stem cell development downstream of Notch signaling.

Guiu J, Shimizu R, D'Altri T, Fraser ST, Hatakeyama J, Bresnick EH, Kageyama R, Dzierzak E, Yamamoto M, Espinosa L, Bigas A.

J Exp Med. 2013 Jan 14;210(1):71-84. doi: 10.1084/jem.20120993. Epub 2012 Dec 24.

3.

Identification of novel regulators of hematopoietic stem cell development through refinement of stem cell localization and expression profiling.

Mascarenhas MI, Parker A, Dzierzak E, Ottersbach K.

Blood. 2009 Nov 19;114(21):4645-53. doi: 10.1182/blood-2009-06-230037. Epub 2009 Sep 30.

4.
5.

Highly potent human hematopoietic stem cells first emerge in the intraembryonic aorta-gonad-mesonephros region.

Ivanovs A, Rybtsov S, Welch L, Anderson RA, Turner ML, Medvinsky A.

J Exp Med. 2011 Nov 21;208(12):2417-27. doi: 10.1084/jem.20111688. Epub 2011 Oct 31.

7.

Gata2 is required for HSC generation and survival.

de Pater E, Kaimakis P, Vink CS, Yokomizo T, Yamada-Inagawa T, van der Linden R, Kartalaei PS, Camper SA, Speck N, Dzierzak E.

J Exp Med. 2013 Dec 16;210(13):2843-50. doi: 10.1084/jem.20130751. Epub 2013 Dec 2.

8.

In vivo differentiation of stem cells in the aorta-gonad-mesonephros region of mouse embryo and adult bone marrow.

Tamura H, Okamoto S, Iwatsuki K, Futamata Y, Tanaka K, Nakayama Y, Miyajima A, Hara T.

Exp Hematol. 2002 Aug;30(8):957-66.

PMID:
12160848
9.

Identification of 2 novel genes developmentally regulated in the mouse aorta-gonad-mesonephros region.

Orelio C, Dzierzak E.

Blood. 2003 Mar 15;101(6):2246-9. Epub 2002 Nov 14.

10.

Quantitative developmental anatomy of definitive haematopoietic stem cells/long-term repopulating units (HSC/RUs): role of the aorta-gonad-mesonephros (AGM) region and the yolk sac in colonisation of the mouse embryonic liver.

Kumaravelu P, Hook L, Morrison AM, Ure J, Zhao S, Zuyev S, Ansell J, Medvinsky A.

Development. 2002 Nov;129(21):4891-9. Erratum in: Development. 2003 Jan;130(2):425..

11.

Embryonic stromal clones reveal developmental regulators of definitive hematopoietic stem cells.

Durand C, Robin C, Bollerot K, Baron MH, Ottersbach K, Dzierzak E.

Proc Natl Acad Sci U S A. 2007 Dec 26;104(52):20838-43. Epub 2007 Dec 17.

12.

Stimulation of mouse and human primitive hematopoiesis by murine embryonic aorta-gonad-mesonephros-derived stromal cell lines.

Xu MJ, Tsuji K, Ueda T, Mukouyama YS, Hara T, Yang FC, Ebihara Y, Matsuoka S, Manabe A, Kikuchi A, Ito M, Miyajima A, Nakahata T.

Blood. 1998 Sep 15;92(6):2032-40.

13.

[Current status of study on embryonic hematopoietic development in aorta-gonad-mesonephros -- review].

He WY, Liu B, Mao N.

Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2009 Feb;17(1):243-6. Review. Chinese.

PMID:
19236789
14.

Hematopoietic stem cell maintenance and differentiation are supported by embryonic aorta-gonad-mesonephros region-derived endothelium.

Ohneda O, Fennie C, Zheng Z, Donahue C, La H, Villacorta R, Cairns B, Lasky LA.

Blood. 1998 Aug 1;92(3):908-19.

15.

Role of the microenvironment of the embryonic aorta-gonad-mesonephros region in hematopoiesis.

Nishikawa M, Tahara T, Hinohara A, Miyajima A, Nakahata T, Shimosaka A.

Ann N Y Acad Sci. 2001 Jun;938:109-16. Review.

PMID:
11458497
16.

The role of apoptosis in the development of AGM hematopoietic stem cells revealed by Bcl-2 overexpression.

Orelio C, Harvey KN, Miles C, Oostendorp RA, van der Horn K, Dzierzak E.

Blood. 2004 Jun 1;103(11):4084-92. Epub 2004 Feb 12.

17.

Detailed characterization of the human aorta-gonad-mesonephros region reveals morphological polarity resembling a hematopoietic stromal layer.

Marshall CJ, Moore RL, Thorogood P, Brickell PM, Kinnon C, Thrasher AJ.

Dev Dyn. 1999 Jun;215(2):139-47.

18.

Functional and molecular characterization of mouse Gata2-independent hematopoietic progenitors.

Kaimakis P, de Pater E, Eich C, Solaimani Kartalaei P, Kauts ML, Vink CS, van der Linden R, Jaegle M, Yokomizo T, Meijer D, Dzierzak E.

Blood. 2016 Mar 17;127(11):1426-37. doi: 10.1182/blood-2015-10-673749. Epub 2016 Feb 1.

19.

In vitro expansion of murine multipotential hematopoietic progenitors from the embryonic aorta-gonad-mesonephros region.

Mukouyama Y, Hara T, Xu M, Tamura K, Donovan PJ, Kim H, Kogo H, Tsuji K, Nakahata T, Miyajima A.

Immunity. 1998 Jan;8(1):105-14.

20.

Endothelium and NOTCH specify and amplify aorta-gonad-mesonephros-derived hematopoietic stem cells.

Hadland BK, Varnum-Finney B, Poulos MG, Moon RT, Butler JM, Rafii S, Bernstein ID.

J Clin Invest. 2015 May;125(5):2032-45. doi: 10.1172/JCI80137. Epub 2015 Apr 13.

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